Part J: Lecture 27

Question 1

Hardy-Weinberg Equilibrium (HWE) (def.)

Answer 1

simple formula of genotype frequencies in a population which remain constant between generations in the absence of disturbance by outside factors

Question 2

HWE works with ____ genes that have ____

Answer 2

autosomal
two alleles

Question 3

HWE: Allele frequencies formula

Answer 3

f (A) = p
f (a) = q
p + q = 1

Question 4

HWE: Genotype frequencies formula

Answer 4

f (A/A) = p^2
f (A/a) = 2pq
f (a/a) = q^2
p^2 + 2pq + q^2 = 1

Question 5

HWE is for population in ____

Answer 5

stable equilibrium

Question 6

HWE allele counting method used when ___

Answer 6

-pop’n isn’t in HWE :when the allele freq is n’t stable
-when people will certain genotype are more likely to die

Question 7

HWE allele counting method

Answer 7

f(allele) = (homozygous for allele X 2) + (heterozygous for allele X 1) / (people X 2)

Question 8

probability child is affected = ?

Answer 8

prob (parent has) x prob (it transmits) x ……

Question 9

HWE with X-linked genes

Answer 9

add …
f(A/Y) = p
f (a/Y) = q

Question 10

HWE with three alleles

Answer 10

add …
f(A1) = p f(A2) = q f(A3) = r
p + q + r =1
p2 + q2 + r2 + 2pq + 2pr + 2qr = 1