Passmed revision Jan 2019 Flashcards

(45 cards)

1
Q

What is rheumatoid arthritis?

A

Chronic inflammation of synovial fluid

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2
Q

What is osteoarthritis?

A

Wear and tare

RF - age, obesity, family history, trauma, occupation

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3
Q

What features of arthralgia points towards rheumatoid Arthritis?

A

Female
Systemic or bilateral
Morning stiffness
Smaller joints - MCP, PIP

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4
Q

What test are useful with rheumatoid arthritis?

A

Rheumatoid factor

Anti-CCP autoantibodies

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5
Q

What is post thrombotic syndrome?

A

Venous insufficiency after a DVT. This includes various veins, heamosiderin deposits, pruritus, swelling etc.

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6
Q

What ECG changes are there for PE?

A

Sinus tachy - most common
RBBB and R axis deviation
S1Q3T3

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7
Q

What might be seen in systemic sclerosis?

A
Ryanuads phenomenon 
Pigmentation 
Scleroderma 
Tightening of the skin 
Morphea or linea plagues
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8
Q

What is CREST syndrome?

A
Subtype of systemic sclerosis:
Calcinosis 
Raynaud's phenomenon 
oEsophageal dysmotility 
Sclerodactyly
Talengesia
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9
Q

What medication can cause Hypokalaemia, hyponatraemia and hypercalcaemia?

A

Bendroflumethiazide

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10
Q

What is the most common cause of bilateral carpal tunnel syndrome?

A

Rheumatoid arthritis

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11
Q

A patient has B12 and folic acid deficiency. How do you treat and and why?

A

B12 first until at normal levels and then folic acid. This stops folic acid exacerbating B12 deficiency and can precipitate subacute combined degeneration of the cord

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12
Q

What scoring system assess risk of developing pressure sores?

A

Waterlow score

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13
Q

What nerve does Saturday night palsy involve?

A

Radial nerve

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14
Q

What monitoring is needed for amiodarone?

A

CXR initially

TFT and LFT every 6 months

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15
Q

Name some common causes of nephritic syndrome?

A

Alports syndrome
Goodpastures syndrome
IgA nephropathy

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16
Q

Name some common causes of nephrotic syndrome?

A

Minimal change
Diabetic
Membraneous glomerulonephritis
Focal segmental glomerulosclerosis

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17
Q

What is the most common nephrotic syndrome?

A

Minimal change, most common in children

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18
Q

What type of renal disease is post-streptococcus glomerulonephritis?

A

Mixed nephrotic and nephritic syndrome

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19
Q

Kid fall and hit shoulder. After he finds it difficult to abduct fingers and adduct thumb. MLD?

A

T1 klumpke’s paralysis - traction causing T1 break leading to loss of function of intrinsic muscles of the hands

20
Q

Patient has a blood on urine dip as well as coughing up blood. MLD?

A

Goodpastures syndrome (antibodies for glomeruli-basement membrane)

21
Q

Patient has blood on urine dip as well as deafness. MLD?

A

Alports syndrome

22
Q

How can haemophilia and VWD be differentiated on clotting screen?

A

Heamophilia has prolonged PT where as VWD has prolonged PT and APTT

23
Q

Risk factors for MS?

A

smoking
Previous infective mononucleosis
Genetics
Hypovitaminosis D

24
Q

Where would a tumour be for an anterior resection to be appropriate?

A

Proximal rectum - removal of the tumour is performed and then the anterior colon anastomoses with the abdominal wall and the posterior anastomoses with the lower rectum

25
Patient with a known colon tumour develops sudden onset abdominal pain which is believed to be a perforation. What is the most appropriate surgical procedure?
Hartmann's procedure - cuts tumour out and leaves in end colostomy. This can be anastomosed in the future with the rectum.
26
What test is used to test a babies hearing?
Acoustic emission test
27
What investigation would be done if an Acoustic emission test came back as abnormal?
Auditory brainstem response test
28
Bone pain, headaches and hearing loss. Bloods show raised ALP with normal Ca/PO4/TFTs. MLD?
Pagets disease Treat with biphsophonates
29
What test can be done to confirms a diagnosis of hereditary spherocytosis?
EMA binding test
30
Whirlpool sign seen on USS. MLD?
Ovarian torsion
31
Target sign on USS. MLD?
Intersusseption
32
What would he serum HCG/TSH/thyroxine show with a molar pregnancy?
Molar pregnancy have high HCG. This can act like TSH to stimulate the thyroid gland into producing a priamary thyrotoxicosis picture. Answer: high HCG, Low TSH, High thyroxine
33
What is Cushing's traid?
Hypertension Bradycardia Decreased RR = raised ICP
34
Where is the lesion localised? 1) Inferior homonymous quadrantanopias 2) superior homonymous quadrantanopias
1) Parietal lobe | 2) Temporal lobe
35
What can be used for prophylaxis of migraine?
topiramate | propanolol
36
7 yo boy with painful limb for 8 weeks. There is a painful hip which also radiates to the knee. MLD and investigations?
Perthes disease - avascular necrosis of the femoral head. Hip Xray, if negative do MRI
37
12 yo boy with knee pain for 4 weeks. There is pain at the hip with internal rotations which is limited. The knee is clinically normal. MLD and investigation?
Slipped upper femoral epiphysis Hip Xray for surgical fixation
38
What anticoagulant causes prolonged PT?
Warfarin
39
What anticoagulant causes prolonged APPT?
Heparin | Von Willebrands disease
40
What antibodies indicate SLE?
Anti-dsDNA | Anti-smith
41
What is Anti-RO and anti-La most associated with?
Sjorgen's syndrome
42
What is Anti-Scl 70 most associated with?
Systemic sclerosis
43
What is Anti-Jo-1 most associated with?
Dermatomyositis
44
What anti-body is most associated with rheumatoid arthritis?
Anti-CCP not Rheumatoid factor
45
What is temporal arthritis associated with what condition?
Polymyalgia rheumatica