Flashcards in Path 1.2 Necrosis Deck (10):
1
types of necrosis
coagulative,
liquifactive,
caseous,
fat,
fibrinoid,
gangrenous
2
coagulative
preservation of cell outlines of dead cells,
intense staining with eosin, more eosin binding sites bc the cell is dying
3
liquifactive necrosis
tissue turns to liquid
4
liquifactive necrosis etiology
occurs in absess (liquid-pus--a collection of neutrophils),
also occurs in the CNS (bc the brain when its injured does everything it can to maintain its 3D structure - surrounding brain tissue froms a gliosis to try and keep the 3D structure in the brain - by forming scars
5
caseous necrosis
cheese-like (cream cheese)
6
caseous necrosis etiology
majority is due to granulomas inflammation and TB.
Some fungi can also form this, this is the macrophages forming this by releasing cytokines that kill the tissue in the particular area
7
fat necrosis
chalky white lesion - you get soaponification of fat liberating the fatty acid that react with calcium to form calcium salts in fatty acid.
Drop in calcium concentration is something you would see in fat necrosis
8
fat necrosis example
injury to pancreas and it releases enzymes like lipases,
the lipases react with the fatty deposits in the omentum
9
ex 2 of fat necrosis
fatty area of the body subjected to trauma
-->whole area of fat dies and just goes away
10