Patho Chap 3 Flashcards Preview

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Flashcards in Patho Chap 3 Deck (31):
1

Tay Sachs

Inherited lososomal storage disease where the infant is unable to break down glycoproteins

2

Peroxisomes

Smaller than lysosomes, they degrade long fatty acid chans. Acetyl CoA is made from fatty acids by perioxisiomes

3

Methods of Chemical Signaling

3 Gap Junctions, Receptors and Release of signal molecules

4

Gap Junctions

Cardiac cells communicate this way. AP's are transmitted directly from one cell to the next

5

Receptors

Signal molecule binds to the receptor site

6

Release of signal molecules

Ex. Inflamatory Response

7

Methods of Cellular Communication

4. Hormonal Signaling, Neuro Hormonal Signaling, Paracrine Signaling, Autocrine Signaling

8

Hormone Signaling

Hormone travles through blood or Lymph. Ex. Insulin

9

Neurohormonal Signaling

Hormones are released into the blood by neurosecretory neurons. Ex. ADH is produced by the Hypothalamus then transmitted along axons and stored in the pituiatry

10

Paracrine Signaling

Cells secrete signaling molecules to nearby cells

11

Autocrine Signaling

Molecules act back on the cell of origin

12

Adenylyl Cyclase is converted to what by the G protein

cAMP

13

2 common second Messengers

cAMP and Ca++

14

Phases of Cellular Respiration

1. Digestion 2. Glycolosis 3. Citric Acid Cycle

15

Products of Glycolosis

2 pyruvic Acid 2 NADH 2 ATP

16

If inadequate O2 available to what and where is pyruvic acid converted

Converted to lactic acin in the Liver

17

Products of Citric Acid Cycle

1 GTP, 3 NADH 1 FADH2

18

How many ATP are produced from Glycolosis (anerobic)

2 net ATP

19

How many ATP are produced from Oxidative Phosphorilation (aerobic)

26 NET 2.5 ATP per NADH and 1.5 ATP pre FADH2

20

Normal Plasma Osmolality

280- 294 mOsm/ kg

21

Osmolality is measured in?

Kg Weight

22

Osmolarity is measured in

L Volume

23

How much of the electrochemical gradient is caused by the Difference in Na and K

80%

24

How much of the electrochemical gradient is caused but the Na/K pump

20%

25

Normal K in the cell

150 mEq/ L

26

Notmal K outside the cell

5 mEq/ L

27

Normal Na in the cell

14 mEq/L

28

Normal Na outside the cell

140 mEq/L

29

Phases of the Cell Cycle

Interphase --> Mitotic Phase --> Cytokinesis

30

Steps of the Interphase

G0 --> G1 --> S --> G2

31

Steps of the Mitotic Phase

Prophase --> Metaphase --> Anaphase --> Telophase