What happens to K levels in erroneously haemolysed blood?
What is APTT?
Activated partial thromboplastin time
HER2 amplification can be found in which type of cancer?
BRAF mutation can be found in which type of cancer?
Which liver enzymes are cytoplasmic?
AST, ALT, LD
Which liver enzymes are membrane bound?
Which liver enzymes are in the mitochondria?
What does enzyme induction refer to in regards to liver function tests?
Some drugs or alcohol induce increased production of liver enzymes causing elevated LFTs when only normal cell turnover is occurring
Eg Raised GGT due to alcohol induction
Which is liver specific, ALT or AST?
ALT - think L for liver
Which has a shorter half life, AST or ALT?
What are the implications?
AST is shorter (36hrs
to 12hrs) therefore, will be gone faster than ALT
There is more AST than ALT so AST will be higher early on
Normal ALT in hep A infection?