Pharm - Antidotes Flashcards by Ben Rome

Q

Acetaminophen

A

N-acetylcystein (replenishes glutathione)

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Q

AChE inhibitors, organophosphates

A

Atropone + pralidoxime

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Q

Amphetamines

A

NH4Cl (acidify urine)

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Q

Antimuscarinic, anticholinergic agents

A

Phyostigmine salicylate, control hyperthermia

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Q

Benzodiazepines

A

Flumazenil

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Q

B-blockers

A

Glucagon

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Q

Carbon monoxide

A

100% O2, hyperbaric O2

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Q

Copper, arsenic, gold

A

Penicillamine

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Q

Cyanide

A

Nitrate + thiosulfate, hydroxocobalamin

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Q

Digitalis

A

Anti-dig Fab fragments

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Q

Heparin

A

Protamine sulfate

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Q

Iron

A

Deferoxamine, deferasirox

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Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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Q

Methanol, ethylene glycol

A

Fomepizole > ethanol, dialysis

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Q

Methemoglobin

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A

Methylene blue, vitamin C

Q

Opiods

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A

Naloxone

Q

Salicylates

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A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

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A

NAHCO3 (alkalinize urine), dialysis

Q

tPA, streptokinase, urokinase

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A

Aminocaproic acid

Q

Warfarin

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A

Vitamin K, plasma (if active bleeding)

Q

Cyclophosphamide, Ifosfamide

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A

Mesna (coadminister to prevent hemorrhagic cystitis)