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Flashcards in Pharm drug rxn Deck (35):
1

coronary vasospasm

cocaine
sumatriptan
ergot alkaloids

2

cutaneous flushing

vancomycin
adenosine
niacin
Ca channel blockers

3

torsades de pointes

class III (sotalol) and class IA (quinidine) antiarrhythmics

4

agranulocytosis

clozapine
carbamazepine
colchicine
propylthiouracil
methimazole
dapsone

Agranulocytosis Could Certainly Cause Pretty Major Damage

5

aplastic anemia

chloramphenicol
benzene
NSAID
propylthiouracil/methimazole

6

direct coombs positive hemolytic anemia

methyldopa
penicillin

7

hemolysis in G6PD deficient pts

isoniazid
sulfonamides
primaquine
aspirin
ibuprofen
nitrofurantoin

8

megaloblastic anemia

phenytoin
methotrexate
sulfa drugs

9

cough

ACE-I

10

pulmonary fibrosis

bleomycin
amiodarone
bulsulfan

11

acute cholestatic hepatitis, jaundice

erythromycin

12

Hepatic necrosis

Halothane
Amanita phalloides
Valproic acid
acetaminophen

13

Hepatitis

INH

14

gynecomastia

spironolactone
digitalis
cimetidine
alcohol use
ketoconazole

15

hot flashes

tamoxifene
clomiphene

16

hyperglycemia

niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids

17

hypothyroidism

lithium
amiodarone
sulfonamides

18

Fat redistribution

glucocorticoids
protease inhibitors

19

gingival hyperplasia

phenytoin
verapamil

20

gout

furosemide
thiazide
niacin
cyclosporine

21

osteoporosis

corticosteroids
heparin

22

myopathies

fibrates
niacin
colchicine
hydroxychloroquine
Interferon-a
penicillamine
statins
glucocorticoids

23

photosensitivity

sulfonamides
amiodarone
tetra

24

SLE syndrome

hydralazine
INH
Procainamide
Phenytoin

25

Stevens Johnson syndrome

penicillin
ethosuximide
carbamazepine
sulfa drugs
lamotrigine
allopurinol
phenytoin
phenobarbital

26

diabetes insipidus

lithium
demeclocycline

27

fanconi's syndroe

old tetracycline

28

hemorrhagic cystitis

cyclophosphamide
ifosfamide
(prevent with mesna)

29

interstitial nephritis

methicillin
NSAIDs
furosemide

30

SIADH

carbamazepine
cyclophosphamide

31

parkinson sx

antipsychotics
reserpine
metoclopramide

32

seizures

isoniazid
buproprion
imipenem
tramadol
enflurane
metoclopramide

33

anti-cholinergic effets

atropine
TCAs
H1 blockers
neuroleptics

34

disulfiram

metronidazole
1st gen sulfonylureas
cephalosporins

35

nephrotoxicity

aminoglycosides
vancomycin
loop diuretics
cisplatin