Pharm: Heme Drugs Flashcards Preview

Step 1 > Pharm: Heme Drugs > Flashcards

Flashcards in Pharm: Heme Drugs Deck (12):
0

Heparin

Promotes action of anti-thrombin III

1

Fondaparinux

Promotes inhibition of factor Xa by anti-thrombin III

2

Warfarin (Coumadin)

Inhibits vitamin K-dependent carboxylation of factors II, VII, IX, X and proteins C and S

3

Argatroban

Direct thrombin inhibitor (others in this class: bivalirudin, lepirudin)

4

Rivaroxaban

Director inhibitor of factor Xa

5

ASA (Aspirin)

Irreversible inhibitor of COX1 and 2 > decreased prostaglandin synthesis

6

Clopidogrel

Blocks platelet aggregation by irreversibly inhibiting binding of ADP to P2Y12 receptor (other drugs in same class: prasugrel)

7

Cilostazol

Inhibits cAMP phosphodiesterase III > increased cAMP levels > inhibits thromboxane A2 synthesis

8

Dipyridamole

Inhibits uptake of adenosine > increases circulating adenosine > increases cAMP > inhibits thromboxane A2 synthesis

9

Abciximab

Inhibits glycoprotein IIb/IIIa > inhibits binding of fibrinogen and vWF

10

Streptokinase

Promotes conversion of plasminogen to plasmin (thrombolytic)

11

Aminocaproic acid

Inhibits plasminogen activation > inhibits fibrinolysis