Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

foundations of medicine 2 > pharmacology > Flashcards

pharmacology Flashcards

1
Q

what is the role of the autonomic nervous system

A

mediates output from the CNS to the whole body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

describe the basic organisation of the motor ANS

A

2 motor neurones in series: preganglionic and postganglionic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

neurotransmitter in preganglionic neurones

A

acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

neurotransmitter in postganglionic sympathetic neurones

A

noradrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

neurotransmitter in postganglionic parasympathetic neurones

A

acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

where do preganglionic neurones originate in the sympathetic division of the ANS

A

thoracolumbar region

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the role of the sympathetic ANS

A

fight or flight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are nicotinic acetylcholine receptors

A

ligand-gated ion channels activated by acetylcholine, involved in cholinergic transmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are muscarinic cholinoceptors

A

G-protein coupled receptors activated by acetylcholine in parasympathetic transmission.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are adrenoceptors

A

G-protein coupled receptors activated by adrenaline/noradrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

name the 2 main classes of adrenoceptors

A

alpha and beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are b1 adrenoceptors coupled with

A

Gs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are b2 adrenoceptors coupled with

A

Gs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are a1 adrenoceptors coupled with

A

Gq

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are a2 adrenoceptors coupled with

A

Gi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

role of b1 adrenoceptors

A

increase heart rate and force of contraction

17
Q

role of b2 adrenoceptors

A

relaxation of bronchial and vascular smooth muscle

18
Q

role of a1 adrenoceptors

A

contraction of vascular smooth muscle

19
Q

role of a2 adrenoceptors

A

inhibition of NA release

20
Q

where do parasympathetic preganglionic neurones originate

A

craniosacral region

21
Q

which kind of receptors is the parasympathetic ANS stimulated by

A

muscarinic cholinoceptors

22
Q

what are M1 receptors coupled with

A

Gq

22
Q

what are M2 receptors coupled with

A

Gi

23
Q

what are M3 receptors coupled with

A

Gq

24
Q

role of M1 receptors

A

increases stomach acid secretion

25
Q

role of M2 receptors

A

decrease heart rate

26
Q

role of M3 receptors

A

increases saliva secretion
increases contraction of visceral smooth muscles in the bronchioles

27
Q

how can vascular smooth muscle indirectly relaxed

A

via NO

28
Q

MOA of salbutamol

A

selective agonist at B2 -> bronchodilator

29
Q

MOA of atropine

A

competitive antagonist of muscarinic ACh receptors
reverses bradycardia

30
Q

MOA of cocaine

A

blocks U1, increasing the concentration of NA in the synaptic cleft

foundations of medicine 2 (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions