Pharmacology Miscellaneous Flashcards Preview

Wolfpacc Clues Complete > Pharmacology Miscellaneous > Flashcards

Flashcards in Pharmacology Miscellaneous Deck (13)
Loading flashcards...
1
Q

-Azole

A

Drug Class: antimicrobial
Category: Ergosterol synthesis inhibitor
Example: Ketoconazole
Inhibits fungal (ergosterol) synthesis by inhibiting cyt. P-450 enzyme

2
Q

-bendazole

A

Drug Class: Antimicrobial
Category: antiparasitic/antihelminthic
Example: Mebendazole
Inhibits microtubule formation

3
Q

-cillin

A

Drug Class: Antimicrobial
Category: transpeptidase (penicillin-binding protein)
Example: ampicillin
Used in combination with cavulanic acid to protect against destruction of Beta-lactamase
(H. influenzae, H. Pylori, E. coli, Listeria, Proteus, Salmonella, Shigella, and other enterococci)

4
Q

-cycline

A

Drug Class: Antimicrobial
Category: protein synthesis inhibitor
Example: tetracycline
Limit CNS penetration (bind to 30S and prevent attachment of aminoacyl-tRNA)
(Borrelia burgdorferi, M. Pneumoniae, Rickettsia, Chlamydia, and acne)

5
Q

-navir

A

Drug Class: Antiviral
Category: protease inhibitor
Example: ritonavir
HIV Therapy (Ritonavir boosts concentration of other HIV drugs by inhibiting cyt. P-450)

6
Q

-ovir

A

Drug Class: Antiviral
Category: DNA polymerase inhibitor
Example: acyclovir
Inhibit viral DNA polymerase by chain termination

7
Q

-thromycin

A

Drug Class: Antimicrobial (bacteriostatic)
Category: macrolide antibiotic
Example: Azithromycin
Inhibits protein synthesis by blocking translocation (macro-slidessss)

8
Q

-azine

A

Drug Class: CNS
Category: Typical Antipsychotic
Example: Thioridazine

Blocks dopamine D2 receptor (increases cAMP)
(Schizophrenia, psychosis, bipolar, delirium, Tourette syndrome, huntington, OCD)

9
Q

-barbital

A

Drug Class: CNS
Category: barbiturate
Example: phenobarbital

Facilitate GABA-A action by increasing duration of Cl− channel opening, thus decreasing neuron firing (sedative for anxiety, seizures, insomnia)

10
Q
  • ipramine

- triptyline

A

Drug Class: CNS
Category: TCA
Example: Imipramine, Amitriptyline

TCAs inhibit 5-HT and NE reuptake.

11
Q

-apine

A

Drug Class: CNS
Category: Atypical Antipsychotics
Example: clozapine, quetiapine

Varied effects on 5-HT2, dopamine, and alpha/H1 receptors
(Schizophrenia, bipolar, OCD, anxiety, depression, mania, tourette’s)

12
Q

-triptan

A

Drug Class: CNS
Category: 5-Ht agonist
Example: Sumatriptan

Inhibits trigeminal nerve activation (prevents vasoactive peptide release-> induce vasoconstriction)
Used for acute migraine/cluster headaches

13
Q
  • zepam

- zolam

A

Drug Class: CNS
Category: Benzodiazepine
Example: Diazepam, Alprazolam

Facilitate GABA-A action by increasing frequency of Cl- channel opening (just like Barbiturates)
Used commonly for alcohol withdrawal; anxiety, seizures, eclampsia(pregnant woman-seizures)