Physio II Lecture 1B Flashcards Preview

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Flashcards in Physio II Lecture 1B Deck (103):
1

The nervous system is divided into three parts. Name them

CNS, PNS, ANS

2

The CNS consists of _____

Structures arising directly from the neural tube. Includes: Brain and spinal cord

3

The PNS consists of ______

cranial nerves and spinal nerve

4

The ANS consists of_______

sympathetic and parasympathetic

5

Define CNS

the CNS consists of unpaired, bilaterally symmetrical structures extending along the longitudinal axis of the midsagittal plane of the body

6

What is a brain?

Sorts through and properly routes incoming sensory info. Initiates controls and coordintes most muscular activity except simple reflexes
Site of origin of 12 cranial nerve pairs

7

What 4 pairs of cranial nerves carry parasympathetic fibers?

III, VII, IX, X

8

What are the general functional categories of the brain

sensory
motor
cognitive

9

Define spinal cord

It is the first CNS structure encountered by most incoming sensory info except sensory fibers in cranial nerves. It is the last relay station for most motor information except ANS motor fibers. It is the site of coordination of most reflex arcs

10

Define peripheral nervous system

It is made up of transmission pathways carrying info between the CNS an external/internal environment. Has afferent pathways and efferent pathways

11

What carries info to the CNS

afferent (sensory) pathways

12

What carries information FROM CNS

efferent (motor) pathways

13

How many cranial nerves are included in the PNS?

12

14

How many spinal nerves are included in the PNS?

31 of the PNS

15

PNS has sensory receptors in _____

the skin and wall of the gut tube as well as in tendons and skeletal muscles

16

PNS motor end plates are between ______

motor neurons and skeletal muscle fibers

17

ANS may be considered a subdivion of _________

the PNS

18

ANS is entirely _________

motor

19

ANS innervates ______

smooth muscle and glands (viscera)

20

ANS sympthetic system is also called the ______ and ________

fight or flight
also called thoracolumbar

21

ANS prasympathetic is called _____ and _______

feed and breed
also called craniosacral

22

What is the cell body of a neuron?

It is part of a neruon that encloses the nucleus and other organelles necessary to maintain and repair the neuron
Has a trophic unit and perikaryon

23

What are dendrites of a neuron?

Branches off the cell body that carry information to the cell body: Receptive unit
Characteristics: -usually several to many dendrietes per neuron
-relatively short, compared to the axon
-often branched
***have receptors for neurotransmitters
***conduct local potentials

24

What is the axon of a neuron?

The conductive unitthe neuron that carries info to another neuron or muscle cell

25

What are axon characteristics?

Usually relatively long
Single (one per neuron)
Conducts action potentials (nerve impulse)
Releases neurotransmitters

26

What are telodendria?

-Short branched processes at axon ends
-They give off endings called terminal boutons

27

axons may have what type of branches?

collateral

28

what is the cell membrane of the axon called?

axolemma

29

what is the cytoplams of the axon called?

axoplasm

30

what does the axon contain?

mitochondria, neurofilaments, and neurotubules

31

axon is covered by a __________

neurolemma

32

neurolemma is made up of _________ and is often________. And the ______ is formed by ___ ____

The neurolemma is made up of Schwann cells and is often myelinated. And the myelin is formed by Schwann cells

33

What is the ONLY part of the neuron that can be mylinated? Is this part always myelinated?

The Axon
Not all axons are myelinated, even though they are covered by schwann cells

34

What is aggregation of dendrites and nerve cell bodies in CNS called?

Nucelus

35

What is aggregation of dendrites and nerve cell bodies in PNS called?

ganglion

36

What are bundle of fibers (axons) in the PNS called?

Nerve

37

What are bundle of fibers (axons) in the CNS called?

Tract

38

What is the tract in the CNS that crosses from one side to the other called?

commissure

39

What are areas of myelinated axons called?

white matter

40

What are areas of unmylenated axons, cell bodies, and dendrites called?

gray matter

41

What are two spinal nerve branches (rami)?

dorsal primary rami and ventral primary ramus

42

Each spinal nerve in the thoracolumbar region, before branching into _______ gives off two small branches called ______ and _______.What are the functions of the two small branches?

1. primary rami
2. White ramus communicans: Carries myelinated preganglionic fibers
3. Gray ramus communicans: Carries unmyelinated postganglionic fibers back to spinal nerve

43

What is linked together into a long chain on either side of the vertebral column in the thoracolumbar region.Is the site of cell bodies of postganglionic sympathetic nervesAnd is the site of synapes between preganglionic myelinated sympathetic neurons and postganglionic non myelinated sympathetic neurons?

paravertebral ganglia

44

What is a nerve supplying viscera called

splanchnic nerve

45

What is typically found anterior to abdonminal aortaAnd is the site of synapses btw preganglionic myelinated sympathetic neurons and postganglionic non myelinated neurons?

prevertebral ganglion

46

What is a reflex arc?

a pathway that leaves form and returns to the CNS. It consists minimally of a sensory pathway and a motor pathway
Extra: can't override consciously, can't fake it

47

what carries sensations from non-visceral structures such as the skin and skeletal muscle?

Somatic afferent pathways (Sensory)

48

What carries sensation from viscera?

Visceral (splanchnic) afferent pathways(sensory)

49

What carries motor signals to skeletal muscles?

somatic efferent pathways

50

What carries motor signals to smooth or cardiac muscles?

visceral (splanchnic) motor pathway

51

What are association neurons (interneurons)

-some reflex arcs consist only of an efferent neuron and an afferent neuron but most have intervening neurons, called association neurons or interneurons, in the central nervous system that modulate the interactions btw the afferent and the efferent neurons

52

What is associated with synaptics vesicles filled with neurotransmitters

presynaptic membrane

53

What is the synaptic cleft a part of?

part of a synapse

54

What is associated with receptors for neurotransmitters?

postsynaptic membrane

55

What are pathways consisting only of afferent neurons and efferent neurons and each pathway has a single synapse

monosynaptic pathways

56

What pathways include interneurons as well as afferent and efferent neurons and each pathway has multiple synapses?

polysynaptic pathways

57

Depending on synaptic activity, a neuron may be in one of three physiologic states.What are the three states and explains what is happening in each state?

1. Resting- cell body potential is about -65 mv
2. Excited- cell body potential is more positive; about -45. Typically due to influx of Na ion
3. Inhibited- cell body potential is more negative than at rest;about -70. Typically due to influx of Cl ion or efflux of K ion

58

What refers to the sequence of structures invloved in the transmission of a sensory signal from the peripheral receptors to higher brain centers

somatosensory axis

59

What are components of the somatosensory axis pathway?

peripheral receptors
afferent neurons
spinal cord or brainstem
reticular substance- medulla, pons, mesencephalon
cerebellum
thalamus
somesthetic areas of cerebral cortex

60

How are afferent neurons arranged?

In a series of three:
primary afferent neurons- synapse in the posterior horns of spinal cord or sensory nuclei in the brain
secondary afferent neurons- synapse in the thalamus
tertiary afferent neurons- synapse in the somesthetic areas of cerebral cortex

61

the skeletal motor nerve axis refers to _____

the sequence of structures involved in the transmission of an action potential from the higher brain centers to skeletal muscles

62

skeletal motor nerve axis includes ________

motor cortex of cerebrum
Efferent pathways effectors- skeletal muscles

63

What is made up of upper motor neurons extending form cortical areas to the anterior horns of the spinal cord and its alpha motor neurons (lower motor neruons) are extending to the skeletal muscles?

Skeletal motor nerve axis efferent pathways

64

What are smooth muscles and glands supplied by?

ANS and have a somewhat different pathway compared to skeletal motor nerve axis

65

What are the processing areas of the skeletal motor nerve axis?

basal ganglia(nuclei) in telencephalon
thalmus in the diencephalonspinal cord reflexes

66

Acetylcholine is secreted by what neurons?And are they excitatory, inhibitory, or both?

pyramidal cells (cerebral cortex)
some neurons in the basal nuclei
alpha motor neurons
preganglionic nuerons of ANS
postganglionic neurons of the parasympathetic system
some postgaglionic neurons of the sympathetic system

They are usually excitatory

67

norepinephrine is secreted by what neurons?And are they excitatory, inhibitory, or both?

many neurons located in brain stem and hypothalamussome neurons located in the pons (i.e., locus ceruleus)
most postgaglionic nuerons of the sympathetic system.
They can be both

68

Dopamine is secreted by what neurons?And are they excitatory, inhibitory, or both?

neurons originating in substantia nigra
Usually Inhibitory

69

Glycine is secreted by what?And are they excitatory, inhibitory, or both?

synapses in the spinal cord
ALWAYS inhibitory

70

GABA secreted by ____?And are they excitatory, inhibitory, or both?

many areas in the spinal cord and cerebral cortex
Always inhibitory

71

Glutamate secreted by ______?And are they excitatory, inhibitory, or both?

many sensory pathways entering the CNS
many areas of cerebral cortex
ALWAYS Excitatory

72

READ pg 557

READ IT!

73

what may extend out for a considerable distance?

dendrites... they can receive signals from a large spatial area around a motor neuron

74

What cannot transmit action potentials?

Dendrites... they use electronic conduction instead

75

What are long and membranes are thin?

Dendrites... partially permeable to K and Cl ionssome potential lost due to leakage

76

What occurs in a dendrite due to gradual loss of the potential as the depolarization spread from the site of initiation?

decremental conduction
The signal becomes weaker as it gets farther away from site of initiation
This is in opposition to action potentials which are constantly renewed along the length of the axon and therefore do not decrease in strength

77

What is direct spread of electrical currect by ion conduction in the dendritic fluids without generating action potential?

electrontonic conduction

78

What results from electrotonic conduction?

few voltage gated Na channels in dendritic membranes
thresholds too high for action potentials to occur

79

What is defined as the summated degree of excitatory drive to the neuron?

excitatory state

80

When does the excitatory state occur?

When there is a higher degree of excitation compared to inhibition.

81

When does the inhibitory state occur?

When there is a higher degree of inhibition compared to excitation.

82

What is firing rate

as long as the excitatory rate of a neuron remains above the threshold for excitation, the neuron will fire repetitively

83

The firing rate depends on the

normal excitatory rate and on the changes in the excitatory rate due to superimposition of additional excitatory or inhibitory signals

84

What refers to the time it takes to transmit a signal form a presynaptic neuron to a postsynaptic neuron?

synaptic delay

85

What does a synaptic delay depend on?

-time it takes to release the neurotransmitter from the presynaptic neuron
-time it takes for the neurotransmitter to diffuse across the synaptic cleft
-how the neurotransmitter acts on the postsynaptic membrane
-the time it takes for the receptor to increase membran permeability
-time it takes for the inward diffusion of Na ions

86

What are the parts of a neuron?

Cell body, dendrites, and axon

87

What do terminal boutons contain?

Synaptic vesicles filled with neurotransmitters

88

What will not summate to produce an action potential on a postsynaptic neuron?

Simultaneous firing of only a few synapses

89

What can cause superimposed action potential on the postsynaptic neuron?

Can be caused by the simultaneous firing of many synapses

90

What structures are processing areas of the skeletal motor nerve axis?

The basal ganglia (nuclei) in the telencephalon
Thalamus in the diencephalon
Spinal cord reflexes

91

What are dendritic membranes partially permeable to?

Potassium and chloride ions

92

what is main cause of lost in dendrite potential?

Leakage

93

What are the two sources of blood supply to the brain?

Vertebral arteries and internal carotids

94

What is the pathway of vertebral arteries?

First branches of the subclavian arteries
Ascend through the transverse foramina of CV 1-6
Pass through foramen magnum
Unite at caudal border of pons to form basilar artery
The basilar artery gives off cerebellar arteries and then divides into two posterior cerebral arteries

95

What is the pathway of internal carotids?

Terminal branches of the common carotids
Enter cranial cavity through carotid canal in temporal bone

96

What is the Circle of Willis?

A pentagonal-shaped circle of arteries on the ventral surface of the brain that unites the two vertebral and the the two internal carotid arteries

97

What is an important anastomosis between the two vertebral and two internal carotid arteries?

Circle of Willis

98

What are the components of the Circle of Willis?

Posterior cerebral arteries
Posterior communicating arteries
Internal carotids
Anterior cerebral arteries
Anterior communicating artery (unpaired)

99

What are the terminal branches of the basilar artery?

Posterior cerebral arteries

100

What connects the posterior cerebral arteries to the internal carotids?

Posterior communicating arteries

101

What gives off anterior and middle cerebral arteries?

Internal carotids

102

What branches off internal carotids?

Anterior cerebral arteries

103

What connects the two anterior cerebral arteries?

Anterior communicating artery (unpaired)