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Epidemiology > Polyomavirus > Flashcards

Polyomavirus Flashcards

1
Q

Polyomavirus

General Characteristics

A
  • Linear dsDNA
  • icoshedral, no envelope
  • Oncogene
  • Stenoxen (except in birds)
  • Hidden, latent infection
  • Higly resistant
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2
Q

Budgerigar Fledgeling Disease / French Moult

Species Affected

A

Budgerigars, parrots, falcons

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3
Q

Budgerigar Fledgeling Disease / French Moult

Most susceptible

A

10-28 do

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4
Q

Budgerigar Fledgeling Disease / French Moult

Clinical Signs

A
  • Oedema, ascites, nephritis and hepatitis, haemorrhages
  • Acute- high mortality
  • Survivors: growth stop, feather growing problems
  • Subclinical in elderly
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5
Q

Hemorrhagic Nephritis and Enteritis of Geese

Species Affected

A
  • Geese

* Muscovy ducks are susceptible and may be carriers

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6
Q

Hemorrhagic Nephritis and Enteritis of Geese

Most susceptible (age)

A

2-10 wo

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7
Q

Hemorrhagic Nephritis and Enteritis of Geese

Occurrence

A

Hungary-> Europe

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8
Q

Hemorrhagic Nephritis and Enteritis of Geesese

Spread

A
  • Contact with sick animal, faeces, urine, fomites

* Vertical transmission

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9
Q

Hemorrhagic Nephritis and Enteritis of Geese

Pathogenesis

A
  • PO/intransal-> viraemia-> endothelium, lympoid cells, gut, kidneys, mm
  • Virus shed in faeces&urine
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10
Q

Hemorrhagic Nephritis and Enteritis of Geese

Primary Replication

A
  • Dividing cells of lymphoid tissue around parhynx

* Incubation: 7d

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11
Q

Hemorrhagic Nephritis and Enteritis of Geese

Target Organs

A

Endothelium of BV

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12
Q

Hemorrhagic Nephritis and Enteritis of Geese

Clinical Signs

A
  • Death mostly (2-10wo) without any CS
  • Or CNS signs hrs before (shaking head, coma) and bloody diarrhea
  • Surviving birds are presistently infected
  • Chronic: uric acid crystals
  • Elderly infect birds without any symptoms
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13
Q

Hemorrhagic Nephritis and Enteritis of Geese

Pathology & Histopathology

A
  • Subcutaneous edema
  • haemorrhaged throughout the body
  • Ascites
  • Necrosis tubular epithelium& hemorrhagic, interstitial nephritis
  • Hepatitis& liver degeneration
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14
Q

Hemorrhagic Nephritis and Enteritis of Geese

Diagnosis

A
  • CS, PM, histopathology

* PCR

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15
Q

Hemorrhagic Nephritis and Enteritis of Geese

Treatment

A

No effective treatment

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16
Q

Hemorrhagic Nephritis and Enteritis of Geese

Prevention & Immunity

A
  • Closed flock
  • inactivated vaccine
  • vaccinate breeders before laying period

Epidemiology (16 decks)

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