PP - OCD Flashcards

1
Q

what is OCD

A

obsessive compulsive disorder - an anxiety disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is an obsession

A

persistent, intrusive and recurring thoughts or images

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are compulsions

A

repetitive and ritualistic behaviours that often occur as a result of obsessions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

who experiences what with OCD

A

70% have obsessions and compulsions
20% experience obsessions
10% experiences compulsions
1.2% of the world has OCD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the OCD cycle

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are DSM-5 disorders grouped with OCD

A
  • trichotillomania: compulsive hair pulling
  • hoarding disorder: compulsive gathering of possessions and the inability to part with anything regardless of value
  • excoriation disorder: compulsive skin picking
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the cognitive characteristics of OCD

A
  • obsessive thoughts
  • awareness of irrational, excessive anxiety
  • may partake in strategies to deal with obsessions e.g. praying
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

behavioural characteristics of OCD

A
  • avoidance of the anxiety causing stimulus
  • compulsive behaviours
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

emotional characteristics of OCD

A
  • accompanying depression
  • guilt and disgust
  • anxiety and distress
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the biological explanations of OCD

A
  • genetic explanation
  • brain structure
  • neurotransmitters
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the genetic explanation of OCD

A
  • OCD tends to run in families suggesting a genetic link
  • biopsychologists investigate concordance rates for traits of OCD between family members
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what occurs during twin studies in the genetic explanation

A
  • compares MZ twins with DZ twins
  • if a trait has a higher biological basis - concordance would be higher for MZ, higher environmental basis DZ would be higher
    NEVER 100% CONCORDANCE
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are gene mapping studies in the genetic explanation

A
  • compares the genetic material from OCD suffers with non-sufferers
  • indicates a genetic link but is likely to be polygenic
  • Lenane et al saw a prevalence of OCD in related family members
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is a problem with the genetic explanation

A
  • no one’s really sure what exactly is being inherited
  • never get 100% concordance
  • research suggests some forms of OCD are more genetic than others
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does the brain structure explain OCD

A

the “worry circuit” has a fault - causing irrational responses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the “worry circuit”

A
  • the orbitofrontal cortex sends signals to the thalamus via the caudate nucleus about things that are worrying
  • to get to the caudate nucleus, the cingulate cortex acts as a relay system between the two
  • the caudate nucleus usually regulates information from the OFC
  • when the caudate nucleus is damaged, it fails to suppress minor worry signals so the thalamus is alerted
  • this sends signals to the OFC and confirms the worry
17
Q

difference between the orbitofrontal cortex in normal brain vs. OCD brain

A

N: integrates sensory info, makes decisions and anticipates rewards and punishments
OCD: detects an error when there isn;t one

18
Q

difference between the cingulate cortex in normal brain vs OCD brain

A

N: adds emotional response to thoughts
OCD: adds emotions like disgust and guilt to anxious thoughts

19
Q

difference between the caudate nucleus in normal brain vs. OCD brain

A

N: processes and filters information, removes unwanted thoughts - stabiliser
OCD: fails to filters unwanted thoughts

20
Q

differences between the basal ganglia in normal brain vs. OCD brain

A

N: controls movements, thinking and judgement
OCD: causes reflexes or repetitive behaviour

21
Q

what are neurotransmitters

A

chemical messengers that carry, boost and regulate signals between neurons and other body cells

22
Q

what is the neurotransmitter linked to OCD

A

serotonin - sends mood relevant information - if it does not take place, then mood and mental processes can be affected

23
Q

why do we think serotonin is linked to OCD

A
  • serotonin is said to play a very active role in the orbitofrontal cortex and caudate nucleus
  • low levels may cause abnormal functioning (OCD)
24
Q

specific genes related to OCD

A

COMT gene - reduces the action of dopamine
SERT gene - affects the transport of serotonin

25
what are the 3 drug treatments for OCD
- antidepressants (SSRIs) - SNRIs - benzodiazepines (BZs)
26
characteristics of SSRIs
- most common form of treatments for OCD - inhibit serotonin reuptake - dosage for OCD is higher than for depression - some people do not respond to this medication
27
characteristics of SNRIs
- inhibit serotonin and norepinephrine reuptake - only used if SSRIs don't work as they have more side effects - drugs include amitriptyline
28
characteristics of BZs
- anti-anxiety drugs - increase the action of neurotransmitter GABA - inhibitory neurotransmitter - "slows down" the brain
29
strengths of biological treatment of OCD
- Soomro et al discovered that drugs were more effective than placebos - they actually work - little effort in taking a pill and not very intrusive - doesn't require any motivation to get better - CBT does
30
limitations of biological treatment for OCD
- side effects for SNRIs and BZs can be very harmful - little long term evidence for treating OCD - relapse in often common - selective publication often leads doctors to mistreat patients
31
what does the COMT gene control
reduces the action of dopamine
32
what does the SERT gene control
affects transport of serotonin