Ppis Flashcards
(7 cards)
1
Q
Give examples of PPI
A
Omeprazole
Pantoprazole
Esomeprazole
2
Q
Cautions in PPIs
A
MCGOLF
Magnesium = measure this with drugs thay cause hypomagnesemia
Cancer (masks symptoms of this)
Gi irritations
Osteoporosis
Lupus
Fractures
3
Q
MHRA warning Of ppis
A
Risk of SCLE - lesions when exposed to sunlight
4
Q
Which PPI is safe in pregnancy
A
Omeprazole
5
Q
What is the key interaction that you should avoid in PPIs
A
CLOE
Clopigogrel + omeprazole/ esomeprazole = lowers efficacy of clopidogrel
6
Q
Where are PPIs used
A
Dyspepsia
GORD
NSAID ulcers
Excessive secretion of gastric acid
7
Q
Omeprazole + methotrexate interaction
A
Omeprazole decreases metabolism of methotrexate