Practice Test Flashcards Preview

Blood Bank > Practice Test > Flashcards

Flashcards in Practice Test Deck (108)
Loading flashcards...
1

Where is the paratope located?

the variable regions of the light and heavy chain, at the tip of the Y, form the paratope on the antibody.

2

What is the definition of an autoantibody ?

Reaction of ones own antibodies against one owns antigens

3

What is the definition of an alloantibody?

An antibody that is produced by one individual and reacts with an antigen found in other members of the same species

4

TRUE OR FALSE:
Monoclonal antibodies have homogeneous, restricted nature, are derived from a single clone and are used in diagnostic testing and are frequently used in commercial antiseras

True

5

Which class of antibodies:
Mainly functions as an antigen receptor on B lymphs ?

IgD

6

Which class of antibodies:
Can cross the placenta?

IgG

7

Which class of antibodies:
Responds to allergic reactions?

IgE

8

Which class of antibodies:
First to develop in the immune response?

IgM

9

Which class of antibodies:
Reacts best at body temperatures?

IgG

10

Which class of antibodies:
Forms in petamers or hexamers with molecular mass of 900,000 daltons?

IgM

11

Which class of antibodies provides protection against helminths(worms)?

IgE

12

What subclass of IgG ..
Crosses placenta more readily

IgG1

13

Which IgG subclass ...
Doesn’t cross placenta?

IgG2

14

Which IgG subclass ...
Is the highest percentage present?

IgG1

15

Which IgG subclass ...
Does not activate complement?

IgG4

16

Which IgG subclass ...
Highest activator of complement?

IgG3

17

Which IgG subclass ...
Has the highest affinity for the Fc receptor on phagocytic cells?

IgG1 & IgG3

18

What are the functions of complement?

Promote inflammatory response. Alter biological membrane to cause direct cel lysis or enhance susceptibility to phagocytosis

19

What are the two pathways of complement?

Classical and Alternate

20

What activates complement pathways?

Classical- single IgM or 2+ IgG
Alternate- Bacterial cell walls. Bacterial lipopolysaccarides. Fungal cell walls. Virus infected cells

21

Largest unit in the genetic code is _____________.

Chromosome

22

What is the definition of a gene?

A gene is a locatable sequence of DNA on a chromosome corresponding to an inheritable trait. The remaining DNA sequences on the chromosome have structural purposes or are involved in regulating the expression of genetic information

23

What is the definition of an allele?

Any one of two or more genes occupying a specific position (locus) on a chromosome

24

Genes actually present on an allele regardless of trait expressed is called an individuals __________.

Genotype

25

The expressed characteristic of an allele is called _______.

Phenotype

26

Serological differences due to the result of homozygous or heterozygous alleles are referred to as _________.

Dosage

27

TRUE OR FALSE:
Blood group antigens are expressed as dominant , recessive, or co-dominant?

True

28

Which ABO group gene is recessive?

O

29

What would be the possible ABO blood group of offspring with “A” mother and “O” father ?

AO or OO

30

What antigen is present on and individual with O gene ?

H