Flashcards in Pregnancy & Cystic Fibrosis Deck (15)
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1
Amniotic fluid (AF)
regulates fetus temp, allows fetus movement, serves as influx & efflux of constituents for fetus
2
Amniocentesis
drawing out the amniotic fluid via ultrasonograph
tests:
congenital diseases
neural tube defects
HDFN
fetal pulmonary disease
3
how far along before amniocentesis?
25-26 weeks
only go before that if fearful of a congenital disease & want to abort
4
Neural Tube defects
test mother for AFP, hCG, unconjugated estriol, & inhibin A
acetyl cholinesterase (AChE)
infant should swallow & metabolize AFP, when they do not see an increased AFP in AF & in mother's serum
5
Acetyal Cholinesterase indicates?
indicates infant has spina bifida or open spine
6
Fetal Lung maturity
need surfactant or else alveoli sacs will collapse & not open again due to increased surface tension
7
fetal lung development by 24th week
type I cells
type II cells
as lung matures see increased PG, lecithin
8
type I cells
form alveolar capillary membrane for gas exchange
9
Type II cells
produce & store surfactant needed for alveolar stability and form lamellar bodies
10
L/S ratio
'gold standard' for fetal lung maturity
lecithin/sphingomyelin ratio based on sphingomyelin raises slow & lecithin increases as lung mature
>2.0
11
PG
phosphatidylglycerol or PG & lecithin compared to sphingomyelin levels
immunoassays
12
Fluorescence Polarization
fluorescent dye combinded w/ albumin & surfactant in the AF
albumin stays constant so increase is due to surfactant
13
Lamellar Body Count
newest & most commonly used
use platelet analyzer
as lungs mature, the lamellar bodies increase
30k-40k = mature lung
14
Cystic Fibrosis
autosomal recessive disorder that affects the exocrine glands & causes electrolyte & mucous secretion abnormalities
primary cause of deaeth is pneumonia, secondary to heavy abnormal viscous mucus in lungs leading to blockages & pancreatic insufficiency
15
