Prep 1 Flashcards

1
Q

A 35-year-old woman is moving spontaneously and opening her eyes but uttering only unintelligible sounds. Her husband reports that she has been unwell for about 48 hours. She initially seemed lethargic and a bit vague. This morning her speech was hesitant, and she had difficulty finding the words she was looking for. She has now had 2 generalized tonic-clonic epileptic seizures. She has previously been in good health. Her temp is 39.9 degrees

A

herpes simplex encephalitis

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2
Q

What is often first damaged in diabetic neuropathy?

A

dorsal column (fine touch, vibration and conscious proprioception)

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3
Q

Pain on eating or shaving

A

trigeminal neuralgia

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4
Q

Nerve supply to quadraceps?

A

Femoral nerve

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5
Q

Nerve supply to lateral thigh?

A

lateral cutaneous nerve of the thigh

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6
Q

Nerve damage when doing IM injection at buttock?

A

sciatic nerve

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7
Q

What does sciatic nerve divide into at popliteal fossa?

A
tibial nerve (posterior compartment)
common peroneal nerve (anterior and lateral compartments)
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8
Q

What supplies web space of great toe?

A

deep peroneal nerve

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9
Q

What are the accessory muscles of inspiration and innervation?

A
sternocleidomastoid and scalenous
CN XI (accessory nerve)
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10
Q

What is the recurrent laryngeal nerve a branch of?

A

CN X (vagus)

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11
Q

Where do the left and right recurrent laryngeal nerves loop?

A

Left under arch of aorta

Right under right subclavian artery

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12
Q

CNXII palsy?

A

tongue deviates to affected side

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13
Q

Tremor with past pointing and unsteady gait

A

cerebeller

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14
Q

Resting tremor that disapears when stretching out hand

A

PD

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15
Q

Part of the brain that controls temperature?

A

hypothalamus

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16
Q

Muscle that raises eyebrows and innervation?

A

frontalis muscle

Facial nerve CN VII

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17
Q

Muscles of mastication innervation?

A

trigeminal V3

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18
Q

Visual field defect by pituitary adenoma compressing optic chiasm?

A

bitemporal hemianopia

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19
Q

Nerve supply to medial aspect of the shin?

A
L4
saphenous nerve (femoral)
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20
Q

Sensory nerve fibres associated with dull aching pain?

A

C fibres

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21
Q

What part of the brain is involved in motor actions without conscious control?

A

cerebellum

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22
Q

What pathophysiological cause of headache is suggested when headache is worse in the morning and on bending forward, coughing, sneezing, streaming and lying down?

A

raised intracranial pressure

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23
Q

What is L-dopa metabolised to?

A

dopamine

used in PD

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24
Q

What side does fine touch ascend?

A

ipsilateral (dorsal columns)

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25
What CSF finding supports SAH 6 hours post headache?
xanthochromia
26
Previous hx of optic neuritis, new onset sensory disturbance from T11 downwards. Significant right leg weakness, loss of proprioception and vibration. Left leg numbness and loss of pain and temperature
MS
27
Dermatome lateral border of the foot
S1
28
Dermatome in perianal area
S5
29
Sudden severe headache
SAH until proven otherwise
30
Micrographia is a feature of?
PD
31
What causes adam's-strokes attacks?
lack of blood to the brain due to arrythmias (heart block)
32
Head injury months previously and now increasingly confused?
chronic subdural haematoma
33
test to distinguish haemorrhagic stroke from ischemic
CT
34
What drugs can impair folate absorption and lead to macrocytic anemia?
phenytoin carbamazpine barbiturates
35
Bacterial meningitis following splenectomy
S.pneumoniae
36
Nerve commonly damaged by slipped disc?
L5
37
Rigidity, bradykinesia, resting tremor and intention tremor. Ataxia and positive babinskis
Multi system atrophy
38
Build up of urophorphinogen
Porphyria cutanea tarda
39
Child crying in direct sunlight
erythropoietic protoporphyria
40
Slapped cheek
Parvovirus 19
41
Cluster of shiny red/purple papules with fine white streaks. Itchy. Often on flexor surfaces of arm?
Lichen planus
42
Exclamation point hair?
allopecia
43
1st line treatment for acne rosacea
topical metronidizole
44
1st line treatment for acne vulgaris
topical retinoid (isotretinoin) or benzoyl peroxide
45
What conditions are ass with koebner phenomenan?
psoriasis lichen planus vitiligo
46
Management of impetigo?
topical fusidic acid or oral flucloxacillin if severe
47
Difference between impetigo and erysipelas?
both are superficial skin infections impetigo caused by staph aureus erysipelas caused by strep pyogenes (GAS)
48
What is cellulitis?
deeper dermal infection of skin and soft tissue | caused by strep pyogenes (GAS) and staph aureus
49
Crepitus in the skin?
gas in the skin caused by CO2 produced by anaerobic bacteria in necrotising fascitis
50
What causes staphlococcal scalded skin syndrome?
epidermolytic exotoxin A&B released by staph aureas
51
odland bodies
granular layer
52
polyhedral cells with lots of desmosomes
prickle cell layer
53
commonest sweat gland on the face, role in temperature, moistens palms and soles for grip
eccrine
54
gland affected in acne, androgen surge at puberty stimulates sebum, maintains skin barrier
sebaceous glands
55
scent gland
appocrine
56
hard and densely packed keratin similar to hair
nails
57
Phases of hair growth
anagen catagen telogen
58
transient pressure sensation
pacinian corpuscles
59
pain and temperature sensation
free nerve endings
60
tactile, light touch and vibration sensation in hairless skin
meissners
61
light touch located in hair follicles
merkel discs
62
Waterproof layer of skin
keratin
63
regulation of temperature in skin
blood vessels
64
location of vitamin d metabolism
keratinocytes
65
when do sweat glads develop
at 6 months
66
where are nuclei lost
granular layer
67
hyperkeratosis
increased thickness of keratin layer
68
parakeratosis
retention of nuclei in keratin layer
69
acanthosis
thickening of epidermis
70
spongiosis
oedema between keratinocytes
71
Ash leaf macule
Tuberose sclerosis
72
What virus causes warts?
HPV
73
What is mild acne?
facial open and closed comedomes
74
Management of cellulitis
flucloxacillin (doxycyclin if pen allergic)
75
Management of necrotising fasciitis
surgical debridement
76
Management of ringworm
clotrimazole cream or terbinafine orally if extensive
77
Management of candida skin infections
clotrimazole cream oral fluconazole oral nystatin
78
Treatment of scabies
permethrin cream or malathion lotion ( not in pregnancy or <6months) Treat all family member Apply to skin for 24hrs
79
Treatment options for lice
malathion (toxic) dimeticone (non-toxic, coats the lice) combing
80
Common HPV in wart, genital warts and cervical Ca?
Warts/verrucas 1-4 Genital warts 6&11 Cervical Ca 16&18
81
Management options for warts/verrucas?
self resolving cyrotherapy >7yrs topical salicyclic acid (keratolytic)
82
What is ramsey hunt syndrome?
reactivation of VZV in geniculate ganglion (nerve cell bundle of facial nerve)
83
Most common skin cancer in the UK
BCC
84
Purple lesions on elbows in elderly man
lichen planus