PreTest Review Flashcards

(67 cards)

1
Q

The sex cords which contain epithelia, connective tissue, and smooth muscle come from what layer?

A

Intermediate mesoderm

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2
Q

What give rise to the epithelia of distal organs of the reproductive system and external genitalia?

A

Endoderm of the urogenital sinus

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3
Q

Germ cells migrate from where and are located where by week 6?

A

Yolk sac endoderm into the indifferent sex cords of the Urogenital ridge

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4
Q

In males, the Urogenital sinus endoderm gives rise to epithelia of what?

A

Urethra, prostate, and bulbourethral glands

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5
Q

In female, the endoderm of the urogenital sinus gives rise to what?

A

Epithelium of the lower vagina

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6
Q

The paramesonephric ducts give rise to what in female?

A

Upper portion of the vagina

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7
Q

The fetal portion of the placent forms from the?

A

Trophoblast

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8
Q

What are syncytiotrophoblast cells?

A

Cells in direct contact with maternal tissue

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9
Q

The embryo is separated from the cytotrophoblast via what?

A

Extraembryonic mesoderm

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10
Q

What is a primary villus?

A

Syncytiotrophoblast with cytotrophoblast core

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11
Q

What is a secondary villus?

A

Cytotrophoblast core invaded by extraembryonic mesoderm

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12
Q

What is a tertiary villus?

A

Fetal blood vessels invade the mesoderm

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13
Q

The wall of the allantonis forms into what?

A

The umbilical blood vessels

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14
Q

What is the lineage of Spermatogenesis?

A

Spermatogonia - primary spermatocytes - secondary spematocytes - (completion of meiosis) - spermatids -(spermiogenesis) - mature sperm

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15
Q

What are some of the functions of the Sertoli cells?

A
Maintenance of the blood-testis barrier
Phagocytosis
Secretion of ABP
Inhibin
Mullerian inhibiting hormone
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16
Q

The seminal vesicles do what?

A

Produce fructose and other molecules that activate spermatozoa

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17
Q

What does the prostate do?

A

It is a fibromuscular junction that produces the enzymes responsible for the liquefaction of the ejactulate

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18
Q

The proliferative phase of the menstrual cycle is under the control of what?

A

FSH

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19
Q

The secretory phase of the menstrual cycle is under the control of what?

A

LH

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20
Q

What is the OB conjugate vs diagonal?

A

OB - inside of pubic symphysis

Diagonal - inferior aspect of pubic symphysis

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21
Q

What is the parasympathetic stimulation of the male erection?

A

Cavernous nerves and prostatic plexus (from pelvic splanchnic)

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22
Q

What do Sertoli cells secrete?

A

AMH, Transferrin, Ceruloplasmin, inhibin, ABP

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23
Q

What treats Stress incontinence?

A

alpha-adrenergic antagonist to increase SM contraction

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24
Q

What is the treatment of overactive bladder?

A

Anti-Muscarinic B3 to decrease parasympathetic

Anti-cholinergic

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25
When is the gonadal sex determined? Phenotypic?
Gonad - 6th | Pheno - 7th
26
Where are the 3 locations a kidney stone can lodge?
UPJ, UVJ, and pelvic brim
27
What are antagonist of GnRH in males?
GABA, dopamine, IL-1, prolactin, and Beta endorphin
28
What are the KNDy?
Kisspeptin and Neurokinin - Positive GnRH | Dynorphin - Neg
29
What are the characterisitics of Malakoplakia?
Michaelis-Gutman bodies, decreased phagocyte function, and Chronic bacterial infection?
30
Chondyloma lata?
Syphilis
31
Chondyloma acuminatum?
HPV
32
Gleason Grading?
Prostatic adenocarcinoma
33
Kellogg spladt model of female arousal?
Desire isnt a factor until right before the O
34
Wexner score is for what?
Fecal incontinence
35
Psamomma bodies are what type of surface epithelial?
Serous cystadenocarcinoma
36
Characteristics of Thecoma?
Estrogen secreting and lipid laden
37
Characteristic of endometriosis?
Mulberry-Nodules
38
How can you tell if it is neonatal blood?
Nucleated RBCs
39
What transmits pain from the labia majora?
Round ligament
40
What are the TORCH infections?
TORCH infections are toxoplasmosis, rubella, cytomegalovirus, and herpes simplex virus with the O in TORCH stands for other which includes: coxsackie virus, syphilis, varicella-zoster, HIV, and parvovirus. We now know the “O” should also stand for ebloa virus and zika virus.
41
9 valent HPV is mainly to protect?
Females from cervical cancer
42
The cavernous nerve is ___ while the pudendal is ___?
Parasympathetic; sympathetic
43
Why is there an androgen peak in the second trimester?
To establish an external genitalia
44
Chancroid is caused by?
Haemophylius duceri
45
Polypoid cystitis
Indwelling catheter chronic infection
46
Follistatin?
Inhibits activin
47
Viagra is?
PDE5 inhibitor leading to increased cGMP
48
Ca-125 is an indicator?
Surface epithelial ovarian tumors
49
BRCA1 increases the risk of?
Medullary carcinoma
50
BRCA2 increases risk of?
Male breast cancer
51
Genital tubercle forms?
Glands of clitoris and penis
52
UG folds form?
Labia minora and body of the penis
53
OG groove forms?
Opening of the urethra (M+F) and vagina
54
Labioscrotal swelling forms?
Labia major and scrotum
55
What causes hypospadias?
Failure of the UG folds to fuse
56
What causes epispadias?
Incorrect positioning of the Genital tubercle
57
What increases GnRH in males?
Neuropeptide Y, Leptin and NE
58
What muscle is commonly injured in birthing?
Pubococcygeus
59
Straddle injury may cause bleeding where?
Superficial perineal space
60
Pathology associated with rectouterine fold?
Pregnant uterus can expand and cause lower back pain
61
Spermatogonia are dividing?
Mitotically
62
Spermatocytes are dividing?
Meiotically
63
Why are sperm genetically foreign?
Genetic recombination, haploid gene expression, and creation long after "immunological self" has been determined
64
Prolactin binding to Leydig cells does what?
Increases LH receptors
65
Angle by which the ureter enters bladder?
Oblique so it doesnt let pee back up
66
blastocele cavity becomes?
Yolk sac cavity
67
Fluid filled space between bilayer embryonic germ disc and trophoblast?
Amniotic cavity