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Molecular BIO > Proteins of cytoskeleton > Flashcards

Proteins of cytoskeleton Flashcards

1
Q

Formin

A
  1. actin subunit protein

2. nucleates assembly. stays at (+) end

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2
Q

Thymosin

A

actin protein subunit that prevents filament assembly

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3
Q

Profilin

A

actin protein that increases growth at (+) end

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4
Q

ARP Complex

A

actin related protein, nucleates and stays at (-) end.

used by listeria to propel through cytosol

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5
Q

Cofilin

A

actin filament protein. binds ADP-actin—> increase disassembly

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6
Q

Gelsolin

A

cuts sections of actin filaments and binds at the resulting (+) end

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7
Q

Capping Protein

A

prevent assembly/disassembly at the (+) end

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8
Q

Tropomyosin

A

increases stability of filament

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9
Q

What proteins induce bundling of the filaments with different forms?

A

fimbrin, alpha actinin, filamin, spectrin, ERM

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10
Q

Staminin

A

tubulin dimer protein

prevents subunit assembly into polymer

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11
Q

gamma-TuRC

A

tubulin dimer protein

nucelates assembly and stays at (-) end

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12
Q

TIPS

A

associate with (+) end and links microtubule to other structure

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13
Q

Kinesin 13

A 
microtubule protein
catastrophe at (+) end
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14
Q

Katanin

A

microtubule protein

sever microtubule

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15
Q

MAPS

A

stabilize microtubule, by side binding

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16
Q

XMAP215

A

stabilize (+) end and enhance microtubule growth

17
Q

Tau, MAP2

A

cause bundling of microtubule

18
Q

plectin

A

link microtubule to intermediate filaments

19
Q

Where do microtubule nucleate from?

A

microtubule organizing centers, that originate by random collision of alpha, beta, gamme subunits

20
Q

What is the function of centrioles?

A

organize the centrosome matrix to provide proper cell strucutre during duplication

21
Q

The nucleation site of microtubules is (+) or (-)?

A

(-). the positive region will grow out of the MTOC

Molecular BIO (24 decks)

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