Proteins of cytoskeleton Flashcards Preview

Molecular BIO > Proteins of cytoskeleton > Flashcards

Flashcards in Proteins of cytoskeleton Deck (21):
1

Formin

1. actin subunit protein
2. nucleates assembly. stays at (+) end

2

Thymosin

actin protein subunit that prevents filament assembly

3

Profilin

actin protein that increases growth at (+) end

4

ARP Complex

actin related protein, nucleates and stays at (-) end.
used by listeria to propel through cytosol

5

Cofilin

actin filament protein. binds ADP-actin---> increase disassembly

6

Gelsolin

cuts sections of actin filaments and binds at the resulting (+) end

7

Capping Protein

prevent assembly/disassembly at the (+) end

8

Tropomyosin

increases stability of filament

9

What proteins induce bundling of the filaments with different forms?

fimbrin, alpha actinin, filamin, spectrin, ERM

10

Staminin

tubulin dimer protein
prevents subunit assembly into polymer

11

gamma-TuRC

tubulin dimer protein
nucelates assembly and stays at (-) end

12

TIPS

associate with (+) end and links microtubule to other structure

13

Kinesin 13

microtubule protein
catastrophe at (+) end

14

Katanin

microtubule protein
sever microtubule

15

MAPS

stabilize microtubule, by side binding

16

XMAP215

stabilize (+) end and enhance microtubule growth

17

Tau, MAP2

cause bundling of microtubule

18

plectin

link microtubule to intermediate filaments

19

Where do microtubule nucleate from?

microtubule organizing centers, that originate by random collision of alpha, beta, gamme subunits

20

What is the function of centrioles?

organize the centrosome matrix to provide proper cell strucutre during duplication

21

The nucleation site of microtubules is (+) or (-)?

(-). the positive region will grow out of the MTOC