Most common symptom of EPSE
Akathisia
Management of tardive dyskinesia on antipsychotic
Reduce dose
OR consider BB/benztropine
MZ concordance risk of schizophrenia
50%
What distinguishes unipolar depression with risk of bipolar depression?
Psychotic symptoms/family history (?sleep disturbance)
Mania in response to antidepressant treatment that persists after drug discontinuation
20-40% of those with RF (psychotic features, FHx BPAD, mania with SSRI) develop BPAD, 10% in those without risk factors (higher than adults)