pulmonary anatomy & physiology Flashcards
week 3 (63 cards)
ventilation
act of breating - inspiration and expiration
respiration
gas and fluid exchange
perfusion
flow of blood to alveolar capillaries
nasal cavity
air condution, filter system, humidifier, temp control
- moist, sticky environment (submucosal galnds, goblet cells)
pharynx
pathway between nasal cavity (posterioly) and esophagus
- naso oro and laryngo pahrynx
larynx
bifurcates off pharynx, connecting with the trachea
- prevents aspiration; salling, ventilation and volcalization
when some one is swalling and aspirating what are we worrying about anatomically?
the trachea - anterior to esophagus and posterior to arch of aorta
lower: diffusion
what is acinar units?
Terminal respiratory
- respiratory bronchioles
- alveolar ducts
- alveiol (epithelial cells)
- gas exchange
- surfactant (type II cells)
surfactant - not present until week 24, manages surface tension, prevents alveolar collapse
24 weeks is signifcant bc this is the point where if the baby is born they will try to keep it alive
arterial blood gases
what is normal pH range
7.35-7.45
arterial blood gases
normal PaO2 value range
80-100 mmHg
arterial blood gases
PaCO2 normal value range
35mmHg-45mmHg
arterial blood gases
SaO2 normal percentages
95%-100%
arterial blood gases
normal HCO3 value range
22-26 mEq/L
what is bicarbonate (HCO3)
form of carbon dioxide in the blood
- by product of the body’s metabolism
- carried to the lungs via blood
- regulation is aided by the kidneys
- exhales as CO2
HCO3 = kidneys = metabolic
what are the ABG general rules?
3 things
- if pH/PaCO2 move in opposite directions from normal vlues , it is likely a respiratory problem
- if pH/HCO2 move in same direction from normal value, likely metabolic problem
- determining if pH is uncompensated, partially compensated or fully compensated
compensated=
partilaly compensated=
uncompensated =
compensated= normal pH; abnormal PaCo/HCO3
partilaly compensated= all values will be outsdie the normal range
uncompensated = abnoraml pH
draw uncompensated pH table
perfusion
capillary blood flow throughthe pumonary circulation
- necessary for gas exchange (tissue oxygenation, CO2 release)
perfusion
V/Q match =
balance between airflow and blood flow within lungs
V = ventilation Q = perfusion
what is the optimal V/Q ratio?
.8 (4V:5Q)
any varitions could lead to airway collapse and capillary vasoconstriction
lung properties:
surface tension
surfactant (complex material made of lipids and proteins)
lung properties
compliance
distensibility of the lung tissue
what happens when there is an imbalance with compliance
imbalance –> tissuestiffness, decreased lung expansion
lung properties:
elasticity
lung recoil during expiration