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Pharmacology II > Quiz 1 > Flashcards

Quiz 1 Flashcards

1
Q

Bacterial Cell Wall Synthesis Drugs

A
  • beta-lactams
  • Bacitracin
  • Vancomycin
  • Cycloserine
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2
Q

Cell Membrane Drugs

A
  • Polymyxin B

- Colistin

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3
Q

Protein Synthesis (30s) drugs

A
  • Tetracycline

- Aminoglycoside

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4
Q

Protein Synthesis (50s) drugs

A
  • Chloramphenicol
  • Macrolides
  • Lincosamides
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5
Q

Nucleic Acid Synthesis Drugs

A
  • Fluorquninolones
  • Metronidazole
  • Rifampin
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6
Q

Folic Acid Synthesis Drugs

A
  • Sulfonamides

- Diaminopyrimidines

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7
Q

Enteric Sulfonamides

A
  • Succinylsulfathiazole
  • Sulfasalazine
  • Sulfaquinoxaline
  • Sulfaguanidine
  • Phthalylsulfathiazole
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8
Q

Topical Sulfonamides

A
  • Silver sulfadiazine
  • Mafenide
  • Sulfacetamide
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9
Q

Ophthalmic Sulfonamides

A
  • sulfacetamide
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10
Q

Diaminopyrimidines

A
  • ormetoprim
  • pyrimethamine
  • trimethoprim
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11
Q

beta lactam antibiotics

A
  • penicillin
  • cephalosporin C
  • carbapenems
  • monobactams
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12
Q

Bacteriostatic Drugs

A
  • tetracyclines
  • chloramphenicol
  • macrolides
  • lincosamides
  • sulfonamides
  • diaminopyrimidines
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13
Q

Penicillinase-resistant penicillin (good oral)

A
  • Oxacillin
  • Cloxacillin
  • Dicloxaxillin
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14
Q

Broad-spectrum penicillin

A
  • amoxicillin

- ampicillin

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15
Q

extended spectrum/anti-pseudomonal penicillin

A
  • ticarcillin
  • carbenicillin
  • piperacillin
  • mezlocillin
  • azlocillin
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16
Q

possess cephamycin group and effective against anaerobic microbes

A
  • cefotetan

- cefoxitin

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17
Q

treats opthalamic and mastitis

A
  • cefalonium
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18
Q

metabolized to desfuroylceftiofur

A
  • cefitiofur
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19
Q

fourth generation cephalosporin

A
  • cefepime

- cefquinome

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20
Q

common name for Convenia, long 1/2 life

21
Q

beta-lactamase inhibitor drugs

A
  • cavulanic acid
  • sulbactam
  • tazobactam
22
Q

Adverse effects of aminoglycosides

A
  • nephrotoxicity
  • ototoxicity (cats - vestibular; dogs - auditory)
  • neuromuscular blockade
23
Q

Natural tetracyclines

A
  • chlortetracycline
  • tetracycline
  • oxytetracycline
24
Q

semisynthetic tetracyclines

A
  • doxycycline

- minocycline

25
adverse effects of tetracycline
- esophageal lesions - cats - cardiac arrhythmias - horses - alters commensal microflora - horses - tooth mottling - growth retardation - hypersensitivity and drug fever - cats
26
Chloramphenicol derivatives
- thiamphenicol | - florfenicol
27
adverse effects of chloramphenicol
- does dependent bone marrow suppression - aplastic anemia in humans - gray baby syndrome
28
macrolide drugs
- erythromycin - tilmicosin - tylosin - tulathromycin - tiamulin - azithromycin - clarithromycin
29
macrolides oral absorption
- enteric coated oral formulation
30
macrolides that are Type III
- tulathromycin | - azithromycin
31
lincosamide drugs
- lincomycin | - clindamycin
32
lincomycin treats
- mycoplasma
33
clindamycin treats
- toxoplasma gondii
34
macrolides adverse effects
- oral administration contraindicated in hind gut fermentors
35
fluoroquinolones new generation
- premafloxacin | - pradofloxacin
36
fluroquinolone mechanism of action
- inhibits bacterial DNA gyrase/type II topoisomerase
37
fluroquinolone distribution
- bone - prostate - skin - rapid accumulation in macrophages and neutrophils
38
fluroquinolone adverse effects
- photosensitivity - retinal degeneration - cats - cataracts - seizures
39
bacitracin route and indication
- topical | - feed additive (growth promotor)
40
novobiocin treats
- penicillin resistant staph
41
virginiamycin effective against
- toxoplasma gondii | - feed additive (growth promotor)
42
sulphonamides should not be co-administered with
- methenamine -> forms cyrstaluria
43
growth promotor miscellaneous antimicrobials
- bacitracin - carbadox - virginiamycin
44
topical miscellaneous antimicrobials
- bacitracin - thiostrepton - polymyxins
45
toxicity of sulfonamides
- keratoconjunctivitis - hepatic necrosis - nephrotoxicity - blood dyscrasias
46
breed sensitivity of sulfonamides
- doberman pinschers - hypoglycemia (dog and duck) - latrogenic hypothyroidism (dog)
47
macrolides that treat mycoplasma
- erythromycin (rhod equii & camp) - tilmicosin - tylosin
48
not recommended in food producing animals
- chloramphenicol - nitrofurans - vancomycin - metronidazole

Pharmacology II (13 decks)

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