Quiz 2 Flashcards

1
Q

plasma membrane structure and function

A

structure: lipid bilayer
function: physical barrier, gateway for exchange, communication, and site of attachment

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2
Q

transcellular

A

transport that goes THROUGH the membrane

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3
Q

paracellular

A

transport that goes PARALLEL to the membrane

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4
Q

passive transport

A

materials move down gradient, no energy is required

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5
Q

active transport

A

materials move against gradient, requires energy (ATP)

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6
Q

What are the four types of passive flux?

A

simple diffusion
osmosis
facilitated diffusion
bulk filtration

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7
Q

simple diffusion

A

passive and random motion of molecules in solution
moving from high to low concentration
rapid over short distances
directly related to temp
indirectly related to molecular size and fluid viscocity

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8
Q

osmosis

A

diffusion of water across a selectively permeable membrane
high solute conc.= low H2O conc.
cells with high solute conc. have high osmotic pressures

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9
Q

isotonic solution

A

conc. of solute outside cell=conc inside the cell

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10
Q

hypertonic solution

A

conc. of solute outside cell>conc. inside the cell
water flows out (cell shrinks)

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11
Q

hypotonic solution

A

conc. of solute outside cell<conc. inside the cell
water flows in (cell swells)

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12
Q

aquaporins

A

membrane-transport proteins providing a facilitated pathway for water flow through the membrane

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13
Q

facilitated diffusion

A

“easier diffusion”
movement from high to low conc. through a protein

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14
Q

bulk filtration

A

concentrated movement of large groups of molecules (often including water)
everything moves in the same direction
often occurs in response to pressure

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15
Q

Fick’s law (equation)

A

Jnet=-Ds(dCs/dx)
- jnet= flu
- Ds= diffusion coefficient
- dCs/dx= concentration gradient of solute

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16
Q

Fick’s Law says…

A

flux is PROPORTIONAL to temp, concentration gradient, area, and membrane permeability
flux is INVERSELY proportional to friction, molecule size, fluid viscosity, and membrane thickness

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17
Q

Types of Transporters

A

ion channel
carriers
pumps

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18
Q

Ion channels

A

membrane proteins that, when open, act as a passive conduit for ions through the membrane
cycle between open and closed conformations

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19
Q

Ion channels gated by…

A

leaky
ligand
mechanical “pull”
voltage
some are sensitive to temp-how we detect hot/cold

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20
Q

leaky gated

A

channel randomly opens/closes

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21
Q

ligand gated

A

chemical stimulus opens the channel

22
Q

mechanically gated

A

mechanical stimulus opens the channel

23
Q

voltage

A

change in membrane potential opens the channel

24
Q

Carriers/transporters

A

transport of solutes across a cell membrane
can facilitate active/passive transport

25
mechanistic theme for carriers
conformational changes
26
alternating access model
carriers cycle between multiple conformations in which a solute binding site is accessible on one side of the membrane or the other never an open channel all the way through membrane
27
occlusion state
state where the solute may not access either the inside or the outside
28
Pumps
movement of molecules against concentration gradient
29
Primary Active transport
directly requires ATP movement of one (or more) solutes AGAINST their gradient using chemical energy (ATP)
30
Secondary Active transport
utilizes energy stored in pre-existing conc. gradients movement of one or more solutes down their conc. gradients provides the energy for the movement of other solutes AGAINST their conc. gradients
31
uniport
movement of 1 thing in 1 direction
32
symport
movement of 2+ things in the same direction
33
antiport
movement of 2+ things in different directions
34
Epithelial tissue
appears on surfaces involved in exchange, transport, movement/clearing, protection, secretion, and sensation
35
two types of secretion
duct (exocrine)- outside body ductless (endocrine)- inside body
36
merocrine
secretory products secreted by vesicular exocytosis most common form, often continuous ex. sweat and saliva
37
apocrine
partial cellular breakdown (fragmentation) cytoplasm and vesicular contents secreted ex. milk and underarm sweat
38
holocrine
entire cell lost with secretion stem cells divide to replace lost cells ex. oil glads
39
types of intercellular junctions
tight junctions adhering junctions desmosomes gap junctions
40
tight junctions
"gatekeeper" prevent substances from moving between cells encircle cells near apical surface
41
adhering junctions
actin-filament based systems encircle cells immediately adjacent to all its neighbors located deep to the tight junctions
42
desmosomes
tie cells together allow bending and twisting do not encircle cell provide resistance to stress
43
gap junctions
protein channels that allow rapid communication between cells
44
Connective tissue forms
connective tissue proper (loose and dense) supporting connective tissue fluid connective tissue
45
connective tissue consists of...
specialized cells protein fibers ground substance
46
extracellular matrix is made up of...
protein fibers ground substance
47
muscle tissue function
contract (shorten) when stimulated to create movement
48
three types of muscle tissue
skeletal- multinucleated + striated cardiac- striations + intercalated discs smooth- no striations
49
nervous tissue function
communication and control of the body
50
two types of nervous tissue
neuron- nerve cells capable of initiating/conducting electrical activity neuroglia (glia)- cells that support neurons