Quiz 3 Flashcards
(115 cards)
Dementia is characterized by acquired, persistent impairment of multiple cognitive domains that significantly alters _______, social interaction, occupational function, and the ability to perform ______ activities of daily living.
communication; instrumental
What is the preclinical condition that may suggest a person is at risk for developing dementia?
Mild cognitive impairment (MCI)
Mild cognitive impairment is a ______ stage or condition of intermediate symptoms b/w the cognitive changes associated with healthy aging and the salient cognitive impairments seen in Alzheimer’s disease or other dementias.
transition
What are the two types of mild cognitive impairment?
Amnestic MCI
Non-amnestic MCI
What type of MCI affects memory only?
amnestic
Other cognitive functions are initially affected (e.g., language or executive function) is what type of MCI?
non-amnestic
What is the diagnostic criteria for MCI?
- Self-report of memory problems
- measurable memory impairment on standardized test
- No impairments in reasoning, general thinking skills, or ability to perform activities of daily living.
List the 4 types of dementia.
Alzheimer’s Disease
Vascular Dementia
Dementia with Lewy Bodies
Frontotemporal Dementia
Episodic memory deficits
Working memory deficits
Attention and executive function impairments
language and communication impairments
Are all the earliest symptoms of what type of dementia?
Alzheimer’s disease (AD)
List some modifiable risk factors of AD
diet, exercise, controlled cardiovascular risk
List some NON-modifiable risk factors of AD
older age, positive family history, carrier status for the e4 allele of APOE gene
What language and communication aspects are affected earliest in AD?
lexical retrieval
discourse
What abilities are spared in early dementia?
Orientation to self and to other persons Semantic memory Ability to produce fluent sentences Engage in conversation Frequently follow 2-step to 3-step commands
These are all abilities in what stage of AD?
ability to follow 1-2 step commands
can sustain attention for some time
can make relevant on topic statements or comments about tangible stimuli during conversation
middle-stage
What abilities are present in later-stage AD?
attend to pleasant stimuli (e.g., music, sensory stimulation) for brief periods of time
Vascular dementia is most commonly caused by ischemic or hemorrhagic cerebrovascular disease, ________ disease, or _______ disturbances that damage brain areas vital for cognitive function
cardiovascular; circulatory
What are risk factors associated with vascular dementia?
hypertension hypercholesterolemia (high cholesterol) Type II diabetes mellitus prior history of stroke smoking
Vascular is the _____ most common cause of dementia. (first, second, third)
second
Which type of dementia is related to Parkinson’s Disease? (most commonly diagnosed after age 65)
Dementia with Lewy Bodies (DLB)
What are Lewy Bodies?
abnormal clumps of alpha-synuclein protein
When motor deficits precede cognitive impairment, it may be _________?
Parkinson’s disease
When cognitive impairment precedes motor deficits, it may be _________?
Dementia with Lewy Bodies
The following symptoms are associated to which type of dementia? hallucinations visuospatial impairment sleep disturbance fluctuating attention and vigilance gain imbalances reduced speech rate and fluency executive function impairments
Dementia with Lewy Bodies
Frontotemporal Dementia accounts for 10% of dementia cases, most are diagnosed ______ the age of 65.
before