Quiz #7- Chapters 11 and 12 Respiratory and Digestive System Flashcards

(234 cards)

1
Q

Functions of the respiratory system

A

-gas exchange
-helps to regulate blood ph
-contains receptors for smell
-provides structures
-excretion of some water and heat

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2
Q

Respiration

A

Respiration is defined as the overall process in which
gases are exchanged between the atmosphere, the
blood, and cells of the body.

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3
Q

three steps of respiration

A
  1. Pulmonary ventilation
  2. External respiration
  3. Internal respiration
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4
Q

Pulmonary ventilation

A

Pulmonary ventilation (breathing) is the flow of air into
and out of the lungs

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5
Q

External respiration

A

External respiration – exchange of gases between the alveoli (air sacs) of the lungs and the blood in the
pulmonary capillaries

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6
Q

Internal respiration

A

exchange of gases in the between
the blood and systemic capillaries and tissue cells.

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7
Q

cellular respiration

A

cellular respiration is how your cells turn the food you eat into the energy your body needs to function

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8
Q

how does cellular reparation work

A

Your cells take in oxygen (O2) from the air you breathe.

The cells then use that oxygen to break down food (like glucose) and convert it into a special energy molecule called ATP.

This process also produces carbon dioxide (CO2) as a waste product, which your body then gets rid of when you exhale.

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9
Q

Upper respiratory system

A
  • Nose
  • Nasal cavity
  • Sinuses
  • Pharynx
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10
Q

Lower respiratory system

A
  • Larynx
  • Trachea
  • Bronchial Tree
  • Lungs
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11
Q

Conducting zone

A

interconnecting cavities. This is a
series of tubes and cavities that conduct air into and out
of the lungs

  • Nose, nasal cavity, pharynx, larynx, trachea, bronchi,
    bronchioles, and terminal bronchioles
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12
Q

Respiratory zone

A

Respiratory zone is tissues within the lungs where gas
exchange occurs

  • Respiratory bronchioles, alveolar ducts, alveolar sacs and
    alveoli
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13
Q

how does respiratory system help with sense of smell

A

contains receptors for the sense of smell; filters, warms,
and moistens inspired air

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14
Q

what is inspired air

A

Inspired air is the air that you breathe in through your nose and mouth. This air is made up of different gases, including:

Nitrogen (78%)

Oxygen (21%)

Carbon dioxide (0.04%)

Water vapor

The main job of the inspired air is to provide your body with the oxygen it needs for cellular respiration

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15
Q

otorhinolaryngology

A

The branch of medicine that deals with the diagnosis and
treatment of diseases of the ears, nose, and throat (ENT)

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16
Q

external nares

A

Openings to the exterior of the nose

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17
Q

external portion of the nose

A

is made of cartilage and skin overlying bone and is lined with
mucous membrane. It provides an entrance for air which is
filtered by coarse hairs inside the nostrils.

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18
Q

nasal cavity

A

internal portion of the nose

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19
Q

nasal septum

A

divides the external and internal parts of the nose

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20
Q

paranasal sinuses

A

The paranasal sinuses are air-filled spaces within the bones of your skull, located around your nose.

  • They are lined with mucous membranes that are continuous with the lining of your nasal cavity.
  • They help reduce the weight of your skull.
  • They also serve as a resonant chamber, which means they can affect the quality of your voice!
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21
Q

paranasal sinuses include:

A

Maxillary sinuses (in the cheekbones)

Frontal sinuses (in the forehead)

Ethmoid sinuses (between the eyes)

Sphenoid sinuses (behind the eyes)

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22
Q

nasal cavity functions

A

Air warming

Moistening

Filtering

Olfaction

Sound resonance

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23
Q

pharynx (throat)

A

The pharynx is a muscular, funnel-shaped tube that starts at the back of your nose and extends down into your neck.

functions as a passageway for air and food and is a resonating chamber for producing speech sounds and houses the tonsils

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24
Q

3 sections of the pharynx

A

Nasopharynx
Oropharynx
Laryngopharynx

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25
Nasopharynx
Uppermost portion of pharynx Contains adenoid tonsil Eustachian tube openings
26
Oropharynx
Behind mouth Contains palatine and lingual tonsils Lymphatic tissue for pathogen destruction
27
Laryngopharynx
Most inferior portion Opens to larynx and esophagus Involved in swallowing reflex
28
larynx
voice Box Connects pharynx and trachea Composed of 9 cartilage pieces connected by ligaments
29
components of the larynx
main components: thyroid cartilage epiglottis cricoid cartilage primary: arytenoid cartilages, false vocal cords, and true vocal cords.
30
thyroid cartilage
The thyroid cartilage (Adam’s apple) – largest cartilage found on the anterior sided of the neck
31
epiglottis
The epiglottis is the most superior cartilage in the larynx, it has a flap that closes over the top of the airway when we swallow to prevent food/fluids from going into the airway.
32
The cricoid cartilage
just below the thyroid cartilage. helps prevent the airway from collapsing.
33
what is pitch controlled by
Pitch is controlled by the tension of the vocal folds. If they are pulled taut, they vibrate more rapidly and a higher pitch results when air passes over them. Lower sounds are produced by decreasing the muscular tension.
34
voice box
within the larynx made up of the vocal folds which are two pairs of folds of muscle and connective tissue covered with mucous membrane. * The upper pair is the false vocal cords. * The lower pair is the true vocal folds
35
trachea (windpipe)
πŸ“Œ The trachea extends for 4-5 inches from the larynx down into the thoracic cavity. πŸ“Œ It is supported by C-shaped cartilage rings, which prevent it from collapsing. πŸ“Œ The trachea is lined with ciliated epithelium, which helps trap particles and move them up and out of the respiratory system. πŸ“Œ At the bottom, the trachea splits into the right and left primary bronchi, which lead into the lungs. (left goes to left lung and right goes to right lung)
36
mediastinum
separate the left and right lung medially
37
lobules
lobules are the smallest functional units within the lobes of the lungs. Each lobule contains: Lymphatic vessels Blood vessels (arterioles and venules) Nerves Connective tissues Terminal bronchioles Respiratory bronchioles Alveolar ducts Alveolar sacs Alveoli The alveoli are where the actual gas exchange happens between the air and the blood. The lobules allow the lungs to be divided into these smaller, organized units.
38
lungs
Soft, cone-shaped organ Separated by mediastinum Enclosed by diaphragm and thoracic cage Pleural membrane layers: Parietal pleura (outer, lines the thoracic cavity) Visceral pleura (inner, attached to lung)
39
respiratory membrane
Exchange of gases (O2 and CO2) between the blood and the air in the lungs occurs across the thin respiratory membrane. The respiratory membrane consists of the epithelial cells of the alveolus, the endothelial cells of the capillary, and the two fused basement membranes of these layers
40
alveoli
The alveoli are the only sites of gas exchange between the atmosphere and the blood. * The tiny sacs are clustered at the distal ends of the alveolar ducts. * They are the functional units of the lungs where gas exchange occurs.
41
Alveolar Type I cells
Alveolar Type I cells – made up of simple squamous epithelium, thin walls to diffuse gases
42
Alveolar Type II cells
produce pulmonary surfactant (a lipid rich film) that mixes with the tissue fluid lining to decrease surface tension to permit inflation of alveoli (Wet plastic-bag principle)
43
Alveolar Macrophages
Phagocytize foreign material
44
Pulmonary ventilation
Pulmonary ventilation or breathing, the flow of air between the atmosphere and the lungs, occurs due to differences in air pressure. It involves inspiration and expiration
45
inspiration
inspiration is the process of air flowing into the lungs due to the decrease in pressure inside compared to outside. The diaphragm and intercostal muscles work together to make this happen.
46
process of inspiration
πŸ“Œ During inspiration, the pressure inside the lungs decreases compared to the atmospheric pressure outside. πŸ“Œ This lower pressure inside the lungs causes air from the outside to flow into the lungs. πŸ“Œ The main muscles involved in inspiration are the diaphragm and the external intercostal muscles. πŸ“Œ As these muscles contract, they increase the volume of the thoracic cavity, causing the lungs to expand and air to be drawn in. πŸ“Œ The expansion of the lungs is also aided by the elastic recoil of the lung tissues and the surface tension-lowering effects of pulmonary surfactant.
47
Expiration
expiration is the process of air flowing out of the lungs due to the increase in pressure inside compared to outside. The intercostal and abdominal muscles work together to make this happen.
48
process of expiration
πŸ“Œ During expiration, the pressure inside the lungs increases compared to the atmospheric pressure outside. πŸ“Œ This higher pressure inside the lungs causes air to flow out of the lungs to the outside. πŸ“Œ The main muscles involved in expiration are the internal intercostal muscles, abdominal muscles (like the external oblique, internal oblique, and transverse abdominis), and the muscles that compress the abdomen. πŸ“Œ As these muscles contract, they decrease the volume of the thoracic cavity, forcing the air out of the lungs. πŸ“Œ Expiration is also aided by the elastic recoil of the lung and chest wall tissues, as well as the surface tension-lowering effects of pulmonary surfactant.
49
spirometry
The measurement of different air volumes is called spirometry, and it describes 4 distinct respiratory volumes
50
respiratory cycle
One inspiration followed by expiration is called a respiratory cycle
51
tidal volume (TV)
the amount of air that enters or leaves the lungs during one respiratory cycle is the tidal volume (TV)
52
inspiratory reserve volume (IRV)
During forced inspiration, an additional volume, the inspiratory reserve volume (IRV), can be inhaled into the lungs.
53
inspiratory capacity
IRV + TV gives us the inspiratory capacity.
54
Anatomic dead space
is air remaining in the bronchial tree.
55
Modified Breathing Movements
-coughing -sneezing -sighing -yawning -sobbing -crying -laughing -hiccupping
56
Coughing
A long-drawn and deep inhalation followed by a strong exhalation that suddenly sends a blast of air through the upper respiratory passages; stimulus for this reflex act may be a foreign body lodged in the larynx, trachea, or epiglottis
57
Sneezing
Spasmodic contraction of muscles of exhalation that forcefully expels air through the nose and mouth; stimulus may be an irritation of the nasal mucosa
58
Sighing
A long-drawn and deep inhalation immediately followed by a shorter but forceful exhalation
58
Yawning
A deep inhalation through the widely opened mouth producing an exaggerated depression of the mandible; may be stimulated by drowsiness, fatigue, or someone else's yawning, but precise cause is unknown
59
Sobbing
A series of convulsive inhalations followed by a single prolonged exhalation
60
Crying
An inhalation followed by many short convulsive exhalations, during which the vocal folds vibrate; accompanied by characteristic facial expressions and tears
61
Laughing
The same basic movements as crying, but the rhythm of the movements and the facial expressions usually differ from those of crying
62
Hiccupping
Spasmodic contraction of the diaphragm followed by a spasmodic closure of the larynx, which produces a sharp sound on inhalation; stimulus is usually irritation of the sensory nerve endings of the gastrointestinal trac
63
partial pressure
The pressure of a specific gas in a mixture is called its partial pressure.
64
Air is a mixture of gases
Air is a mixture of gasesβ€”nitrogen, oxygen, water vapor, carbon dioxide, and othersβ€”each of which contributes to the total air pressure.
65
external and internal respiration
In external and internal respiration O2 and CO2 move from areas of higher partial pressure to areas of lower partial pressure
66
External respiration
(pulmonary gas exchange) is the exchange of gases between alveolar air and pulmonary blood capillaries
67
Internal respiration
(systemic gas exchange) is the exchange of gases between systemic tissue capillaries and systemic tissue cells.
68
hypoxia
A deficiency of oxygen reaching tissues
69
oxyhemoglobin
Oxyhemoglobin is like a special delivery truck for oxygen in your blood! πŸššπŸ’¨ Here's how it works: Hemoglobin = Protein in red blood cells πŸ”΄ When hemoglobin picks up oxygen, it becomes "oxyhemoglobin" Over 98.5% of oxygen travels in your blood this way! 🫁 * Oxyhemoglobin is unstable in areas where the concentration of oxygen is low and gives up its oxygen molecules in those areas
70
percentage of oxygen and carbon dioxide in inhaled air
Inhaled air is 21% oxygen and 0.04% carbon dioxide
71
percentage of oxygen and carbon dioxide in exhaled air
Exhaled air is 16% oxygen and 4.5% carbon dioxide
72
Carbon dioxide is transported in three ways
About 7% is dissolved in plasma, 23% combines with the globin of hemoglobin, and 70% is converted to bicarbonate ions (HCO3–)
73
Normal breathing
Normal breathing is a rhythmic, involuntary act even though the muscles are under voluntary control
74
eupnea
normal breathing (12 – 20/min, quiet & easy
75
apnea
no breathing
76
dyspnea
difficulty breathing
77
respiratory center two principal areas
1. The medullary respiratory center in the medulla oblongata (rhythmicity). 2. The pontine respiratory group in the pons (pneumotaxic)
78
inspiratory area
The inspiratory area sends signals to the diaphragm and external intercostal muscles, telling them to contract. This causes inhalation, as air is drawn into the lungs. The inspiratory area works together with other parts of the respiratory center, like the pneumotaxic area in the pons, to regulate the overall rate and depth of our breathing.
79
what sets the basic rythm of respiration
The inspiratory area in the medulla oblongata is responsible for setting the basic rhythm of our breathing. This area contains neurons that send out regular signals to the diaphragm and intercostal muscles, telling them when to contract and relax.
80
Respirations
Respirations refer to the overall process of breathing - the inhalation and exhalation of air in and out of the lungs. This is a vital function that allows our bodies to take in oxygen and get rid of carbon dioxide.
81
Medullary Rhythmicity Centers two groups
dorsal respiratory group (DRG) ventral respiratory group (VRG)
82
dorsal respiratory group (DRG)
The DRG is responsible for the basic rhythm of breathing. Neurons in this area transmit impulses that cause the diaphragm and external intercostal muscles to contract for approximately 2 seconds followed by 3 seconds of inactivity.
83
ventral respiratory group (VRG)
The VRG has a cluster of neurons called the pre-Botzinger complex that acts as a pacemaker for the DRG. This contributes to the regular rhythm of breathing, and as well this area becomes more active when more forceful breathing is required. Neurons in this area then create impulses that stimulate the accessory muscles of breathing.
84
Pontine Respiratory Group (PRG)
The Pontine Respiratory Group (PRG) within the pons modifies the basic respiratory rhythm during periods of exercise and/or speaking.
85
The PRG is made up of:
* Neurons in the Pneumotaxic area that shorten the duration of inspiration so that the rate of respirations increases * Neurons in the Apneustic area that prolong duration of inhalation for long deep inhalation (increased depth of respirations).
86
The 3 main things that stimulate breathing
chemicals lung tissue stretching emotional state
87
These gases are our main stimulus to breathe
If either CO2 or H+ ion concentrations rise, the central chemoreceptors signal the respiratory center, and breathing rate increases. These gases are our main stimulus to breathe
88
Hyperventilation
lowers the amount of carbon dioxide in the blood and therefore impulses will strive to slow respiratory rate.
89
Limbic system
Limbic system – anticipation of activity or emotion can stimulate
90
Proprioception (body position)
Proprioception (body position) – stimulates on start of activity
91
Temperature
Temperature – warming increases respiratory rate
92
Pain
* Sudden pain β†’ apnea * Prolonged somatic pain can increase rate while visceral pain can slow the rate
93
Airway irritation
Airway irritation – cough or sneeze
94
Other Regulatory Factors that Affect Breathing:
*Limbic system *Proprioception (body position) * Temperature * Pain * Airway irritation
95
increase in ventilation during exercise
The abrupt increase in ventilation at the start of exercise is due to neural changes that send excitatory impulses to the inspiratory area in the medulla oblongata.
96
gradual increase in ventilation during moderate exercise
The more gradual increase in ventilation during moderate exercise is due to chemical and physical changes in the bloodstream
97
aging in the respiratory system
- the alveoli, become less elastic and more rigid -the chest wall becomes more rigid as well. The result is a decrease in vital lung capacity - Elderly people are more susceptible to pulmonary diseases such as pneumonia, emphysema, bronchitis, and other pulmonary disorders - Aging also leads to decrease in blood O2 levels, decreased exercise capacity, and decreased macrophage activity
98
Digestion
refers to the mechanical and chemical breakdown of foods so that nutrients can be absorbed by cells.
99
Mechanical digestion
breaking down of food into smaller pieces to increase surface area, consists of mixing waves that macerate food and mix it with gastric juice, forming chyme
100
Chemical digestion
enzymes breaking down complex organic molecules into simpler molecules, with each specific enzyme being specific to the food it will break down
101
gastrointestinal (GI) tract or alimentary canal
is a continuous tube that extends from the mouth to the anus. The GI tract contains food from the time it is eaten until it is digested and absorbed or eliminated from the body.
102
Organs of the gastrointestinal tract
mouth (oral cavity) pharynx, esophagus, stomach small intestine large intestine (also called bowel or colon).
103
length of the GI tract
16.5–23 ft. in living people
104
accessory digestive organs that aid in the processes of digestion
The teeth tongue, salivary glands liver, gallbladder, and pancreas
105
Digestion includes six basic processes:
Ingestion - eating 2. Secretion– release of water, enzymes, acids, & buffers 3. Mixing and propulsion – movement of food products along the GI tract 4. Digestion – mechanical and chemical breakdown of foods 5. Absorption – getting food molecules into the body (blood and lymph) 6. Defecation – elimination of feces
106
Ingestion
eating
107
Secretion
release of water, enzymes, acids, & buffers
108
Mixing and propulsion –
– movement of food products along the GI tract
109
Absorption
getting food molecules into the body (blood and lymph
110
Defecation
elimination of feces
111
The four layers of the GI tract
mucosa submucosa, muscularis, and serosa and peritoneum.
112
parietal peritoneum
lines the wall of the abdominal cavity
113
visceral peritoneum
the visceral peritoneum covers organs in the cavity
114
peritoneum
The peritoneum binds organs to each other and to the walls. Folds within the peritoneum contain blood vessels, lymphatic vessels, and nerves.
115
Parts of the peritoneum
mesentery and greater omentum
116
Greater omentum
is a large protective β€œapron” that is a flap of peritoneum that hangs over the top of the abdominal organs and serves a protective function for the abdominal organs
117
The mesentery
is another part of the peritoneum that binds the small intestine to the posterior abdominal wall. Otherwise, the small intestine is rather loosely secured.
118
Mucosa Layer
Inner layer is the mucosa – a mucous memberane. * Lined with epithelium tissue that is attached to a connective tissue layer and a thin muscular layer. * It protects secretion tissues of the GI tract and carries on and absorption
119
Muscularis Layer
Made up of skeletal muscle in the mouth, pharynx, and upper esophagus as well as the external sphincter. * Smooth muscle layers with inner circular fibers and outer longitudinal fibers make up the rest of the tract. * These muscles propel food through the canal. * The muscular contractions of the GI tract (controlled by impulses from the enteric nervous system – control GI behavior independent of CNS) are called peristalsis. * Mixing movements in the stomach occur when smooth muscle contract rhythmically in small sections. * The ability of the GI tract to mix and move food along its length is called motility
120
peristalsis
The muscular contractions of the GI tract (controlled by impulses from the enteric nervous system – control GI behavior independent of CNS)
121
motility
The ability of the GI tract to mix and move food along its length
122
Serosa Layer
Outer layer = visceral peritoneum * Largest serous membrane of the body. * It protects underlying tissues and secretes serous fluid to keep the GI tract from sticking to other tissues in the abdominal cavity
123
function of the mouth
to receive food and begins mechanical digestion by mastication
124
lips
Lips are highly mobile structures that surround the mouth opening. Contain sensory receptors to help judge the temperature and texture of food
125
what does the mouth or oral cavity consist of
formed by the cheeks (lateral walls), hard and soft palates, lips, and tongue
126
tongue
forms the floor of the oral cavity. It is composed of thick skeletal muscle covered with mucous membrane. The superior surface and lateral areas of the tongue are covered with papillae.
127
Papillae
Papillae are the tiny bumps or projections on the surface of the tongue. They help provide texture and friction to assist with moving food around in your mouth during chewing and swallowing. The papillae contain your taste buds, which allow you to detect different tastes like sweet, sour, salty, and bitter. This helps you enjoy the flavors of the foods you eat! πŸ”πŸ•
128
Lingual tonsils
are lymphatic tissue located in the root of the tongue
129
frenulum
the thing that attaches the tongue to the floor of the mouth
130
cranial nerve #12
Motor impulses come to the tongue via cranial nerve #12
130
lingual lipase
Glands in the tongue secrete lingual lipase which digests triglycerides once in the acid environment of the stomach
131
cranial nerve #7 and #9
hypoglossal and sensory impulses from the receptors in taste buds travel through cranial nerve #7 and cranial nerve #9 – glossopharyngeal.
132
salivary glands
The salivary glands secrete saliva, which moistens and dissolves food particles, binds them together, allows tasting, helps to cleanse the mouth and teeth, and begins carbohydrate digestion
133
three pairs of salivary glands:
parotid submandibular sublingual
134
purpose of saliva
Saliva lubricates food and starts the chemical digestion of carbohydrates.
135
teeth (dentes)
are accessory digestive organs located in bony sockets of the mandible and maxillae
136
tooth consists of three principal portions
crown, root, and neck.
137
Teeth are composed primarily of?
Each tooth consists of a crown and a root, and is made of enamel, dentin, pulp, cementin, nerves, and blood vessels. and are covered by enamel, the hardest substance in the body. * A tooth is held tight in its socket by a periodontal ligament
138
Humans have two sets of teeth
deciduous and permanent
139
mastication
Through mastication, food is mixed with saliva and shaped into a bolus
140
Salivary amylase
Salivary amylase begins the digestion of starches in the mouth
141
soft palate and uvula function
The soft palate and uvula function to close off the nasal cavity during swallowing
141
palatine tonsils
they are lymphatic tissue, help to protect the body against infection
142
palate
forms the roof the oral cavity and has an anterior hard palate and a posterior soft palate
143
pharyngeal tonsils (adenoids)
Another lymphatic tissue mass, pharyngeal tonsils (adenoids), are located on the posterior wall of the pharynx, above the border of the soft palate.
144
Salivary glands contain
Salivary glands contain serous cells that produce a watery fluid with amylase, and mucous cells that produce a lubricating and binding mucus. * Salivary glands receive parasympathetic stimulation that triggers the production of a large volume of saliva at the sight or smell of food.
145
parotid glands
lying in front of the ear, are the largest of the major salivary glands; they secrete a clear, watery fluid rich in amylase
146
submandibular glands
The submandibular glands, located on the floor of the mouth, secrete a more viscous fluid
147
sublingual glands
The sublingual glands, inferior to the tongue, are the smallest of the major salivary glands and secrete a saliva that is thick and stringy
148
pharynx
The pharynx is a cavity lying behind the mouth, The pharynx connects the nasal and oral cavities with the larynx and esophagus and is divided into: * Nasopharynx (top portion) * Oropharynx (middle portion) * Laryngopharynx (bottom portion
149
esophagus
The esophagus is a muscular tube that connects the pharynx (throat) to the stomach. It's about 4-5 inches long and helps move food from your mouth down into your stomach.
150
key things to know about the esophagus are:
It has two sphincters - the upper esophageal sphincter (made of skeletal muscle) and the lower esophageal sphincter (made of smooth muscle). These help control the movement of food. It uses peristalsis, which are wave-like muscle contractions, to push food down towards the stomach.
151
pharynx
The pharynx is a funnel-shaped cavity that connects the nasal and oral cavities to the larynx and esophagus. composed of skeletal muscle and lined by mucous membrane. It's an important part of both the respiratory and digestive systems.
152
parts of the pharynx
Nasopharynx (top portion) Oropharynx (middle portion) Laryngopharynx (bottom portion)
153
The key things to know about the pharynx:
It contains lymphoid tissue like the palatine and lingual tonsils, which help protect against infections. It's involved in swallowing, as the muscles in the pharynx contract to push food from the mouth into the esophagus.
154
bolus
the chewed food mixed with saliva
155
Swallowing consists of three stages
voluntary stage involuntary stage or pharyngeal stage. esophageal stage
156
A voluntary stage
A voluntary stage, from the mouth to the oropharynx the bolus is forced into the oropharynx by the tongue
157
An involuntary stage or pharyngeal stage.
Sensory receptors in the pharynx sense food, breathing is temporarily interrupted when the soft palate and uvula move upward and the epiglottis seals off the larynx and the vocal cords come together
158
esophageal stage
An involuntary esophageal stage. Peristalsis transports the food in the esophagus to the stomach
159
stomach
The stomach is a J-shaped muscular organ located right below the diaphragm.
160
important functions of the stomach:
It receives and mixes food with digestive juices It acts as a holding reservoir for food It slowly propels food into the small intestine
161
The stomach has 4 main regions:
Cardia - surrounds the upper opening Fundus - the upper, left portion Body - the large central portion Pylorus - the lower part leading to the small intestine Can friendly bears play
162
The stomach wall has 4 layers
- mucosa, submucosa, muscularis, and serosa. This allows for mechanical digestion (mixing) and chemical digestion (with enzymes like pepsin).
163
pyloric sphincter.
Between the pylorus and duodenum
164
rugae
When the stomach is empty, the mucosa lies in many large folds, called rugae, which provide more surface area and the ability to expand.
165
The main event of chemical digestion
The main event of chemical digestion in the stomach is the beginning of protein digestion by the enzyme pepsin (chief cells), which breaks peptide bonds between the amino acids of proteins.
166
Mucus
Mucus secreted by mucous cells coats the mucosa, forming a thick barrier between the cells of the stomach lining and the gastric juice
167
Lingual lipase
Lingual lipase produced by the tongue digests triglycerides into fatty acids and diglycerides in the acid environment of the stomach.
168
The stomach wall
The stomach wall is impermeable to most substances. Mucous cells of the stomach absorb some water, ions, and short-chain fatty acids, as well as certain drugs (especially aspirin) and alcohol.
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Gastric glands generally contain 3 types of exocrine cells:
1. Mucous neck cells 2. Chief cells 3. Parietal cells
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Mucous neck cells
Mucous neck cells – produce mucus that protects the stomach lining.
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Chief cells
– secrete pepsinogen which once in contact with hydrochloric acid, becomes activated into pepsin which is an enzyme that digests proteins.
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Parietal cells
Parietal cells – secrete hydrochloric acid and intrinsic factor (required for vitamin B12 absorption from the small intestine).
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G cells
secrete the hormone gastrin into the bloodstream.
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chyme
Following a meal, mixing actions of the stomach turn the food into chyme and pass it toward the pyloric region using peristaltic waves The rate at which the stomach empties depends on the fluidity of the chyme and the type of food
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The pancreas
The pancreas is an organ located behind the stomach. It has both exocrine and endocrine functions
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Exocrine Function of the pancreas:
The pancreas produces digestive enzymes like amylase, trypsin, and lipase that help break down carbohydrates, proteins, and fats. These enzymes are secreted into the small intestine through the pancreatic duct.
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Endocrine Function of pancreas:
The pancreas also contains clusters of cells called the islets of Langerhans that secrete hormones like insulin and glucagon. These hormones help regulate blood sugar levels.
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Some key facts about the pancreas:
It's closely associated with the small intestine and liver. The pancreatic and bile ducts join before emptying into the duodenum. The pancreatic enzymes are released in an inactive form and get activated once they reach the small intestine.
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acini
small clusters of glandular epithelial cells
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Pancreatic juice
Pancreatic juice contains enzymes that digest starch (pancreatic amylase); proteins (carboxypeptidase trypsin, chymotrypsin); triglycerides (pancreatic lipase); and nucleic acids (RNA/DNA)
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Pancreatic enzymes break down all 3 types of complex food molecules. The main enzymes are
Amylase – converts starch to maltose * Trypsin – converts polypeptides to peptides * Lipase – converts emulsified fats to fatty acids and glycerol
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Cholecystokinin
Cholecystokinin from the wall of the small intestine stimulates the release of pancreatic juice with abundant digestive enzymes
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secretin
The hormone secretin, from the duodenum, stimulates the release of pancreatic juice with high bicarbonate ion concentration but few digestive enzymes. This assists with raising the pH and neutralizing the HCl in stomach chyme.
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the liver
The liver is the largest internal organ in the body and is located in the upper right part of the abdomen, behind the stomach. Structurally, the liver is divided into left and right lobes. It has a fibrous capsule and is made up of tiny functional units called hepatic lobules.
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function of the liver
It produces bile, which helps digest and absorb fats in the small intestine. It filters blood and removes toxins, drugs, and other harmful substances. It stores vitamins and minerals like iron and vitamin A. It helps regulate blood sugar levels and metabolism. It breaks down and recycles old red blood cells.
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The gallbladder
The gallbladder is a small sac-like organ located under the liver that stores and concentrates the bile produced by the liver. A sphincter muscle controls the release of bile from the common bile duct
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Bile
Bile is a yellowish-green liquid that hepatic cells secrete. Bile includes water, bile salts, bile pigments, cholesterol, and electrolytes
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The small intestine
The small intestine is a long, narrow tube that connects the stomach to the large intestine. It's about 10 feet long
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The small intestine 3 main sections
Duodenum - the first and shortest section, right after the stomach Jejunum - the middle section Ileum - the final section before the large intestine
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Some key functions of the small intestine:
It completes the digestion of food that started in the stomach. It absorbs the majority of nutrients from the digested food. It has a large surface area with features like villi and microvilli to maximize absorption. It receives secretions from the pancreas, liver, and gallbladder to aid digestion.
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where does absorption take place
About 90% of all absorption takes place in the small intestine. The other 10% occurs in the stomach and large intestine
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Absorption
Absorption is the passage of nutrients from digested food in the gastrointestinal tract into the blood or lymph. It occurs mostly in the small intestine by means of simple diffusion, facilitated diffusion, osmosis, and active transport.
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monosaccharides
monosaccharides are the simplest form of carbohydrates. They are the basic units that make up more complex carbohydrates like disaccharides and polysaccharides. The three main monosaccharides are: Glucose Fructose Galactose These monosaccharides are absorbed directly into the bloodstream from the small intestine. The liver can then convert fructose and galactose into glucose, which is the body's preferred source of energy.
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The large intestine
The large intestine is the final section of the digestive tract, connecting the small intestine to the anus. It's about 5 feet long and 2.5 inches in diameter. The large intestine lacks the villi and digestive enzymes of the small intestine, so it does not absorb nutrients. Instead, it absorbs water and electrolytes to form solid waste (feces) that is then eliminated.
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The main functions of the large intestine are:
Absorbing water and electrolytes from indigestible food matter Storing waste before it is eliminated from the body Producing some vitamins through bacterial action
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The large intestine is divided into several sections:
Cecum (pouch at the beginning) Colon (ascending, transverse, descending, sigmoid) Rectum Anal canal
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defecation reflex action
Defecation is stimulated by a defecation reflex action that forces feces into the rectum where they can be expelled
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teniae coli
Teniae coli are three approximately 8-mm-wide longitudinal smooth muscle bands in the colon wall. 9. They are parallel, equally distributed, and form a triple helix structure from the appendix to the sigmoid colon.
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haustra
Fibers of longitudinal muscle are arranged in teniae coli that extend the entire length of the colon, creating a series of pouches called haustra the small pouches caused by sacculation, which give the colon its segmented appearance. The taenia coli runs the length of the large intestine.
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intestinal phase
The intestinal phase of digestion begins once food enters the small intestine. In addition, gastric motility and gastric secretion decrease in order to slow the exit of chyme from the stomach, which prevents the small intestine from being overloaded with more chyme than it can handle
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Aging and the Digestive System
Decreased secretory mechanisms - The stomach, pancreas, and other organs produce fewer digestive enzymes and secretions. Reduced motility - The muscles of the digestive tract become less coordinated and efficient at moving food along. Loss of strength and tone - The supporting structures and muscles of the digestive organs weaken over time.
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Some specific age-related issues in the digestive system that can develop include:
Loss of taste sensation Hernias Peptic ulcers Constipation Hemorrhoids Diverticular diseases These changes can make digestion and nutrient absorption more difficult for older adults. Maintaining a healthy diet and lifestyle becomes even more important as we age.
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Metabolism
Metabolism refers to all the chemical reactions that occur in the body to sustain life. It's an energy-balancing act between two key processes: Anabolism - The synthesis of complex molecules from simpler substances. This is a constructive process that requires energy. Catabolism - The breakdown of complex organic compounds into simpler ones. This is a destructive process that releases energy.
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Enzymes
Enzymes act as critical catalysts that speed up these chemical reactions in the body.
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The key link between anabolic and catabolic reactions
The key link between anabolic and catabolic reactions is ATP (adenosine triphosphate). Cellular processes convert nutrients into usable energy through complex metabolic pathways like glycolysis, the Krebs cycle, and the electron transport chain.
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Carbohydrates
Carbohydrates, such as sugars and starches, are organic compounds used for sources of energy in the diet. * Carbohydrates are ingested in a variety of forms: starch from grains, glycogen from meat, and disaccharide and monosaccharide sugars from fruits and vegetables
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Malnutrition
Malnutrition is poor nutrition that results either from a lack of essential nutrients or a failure to utilize them; malnutrition may result from undernutrition or overnutrition
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Food molecules absorbed by the gastrointestinal (GI) tract have three main fates:
1. To supply energy for sustaining life processes. 2. To serve as building blocks for the synthesis of more complex molecules, such as muscle proteins, hormones, and enzymes. 3. Storage for future use.
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Nutrients
Nutrients are chemical substances in food that body cells use for growth, maintenance, and repair. Nutrition is the process by which the body takes in and uses nutrients
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The six main types of nutrients are
carbohydrates, lipids, proteins, water, minerals, and vitamins.
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Essential nutrients
are specific nutrient molecules that the body cannot make and must be obtained from the diet
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four principal routes of heat loss from the body to the environment are
1. Radiation 2. Conduction 3. Convection 4. Evaporation
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Heat
Heat is a form of energy that can be measured as temperature and expressed in units called calories. A calorie is the amount of energy required to raise the temperature of 1 g of water 1 C
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Calorie
Calorie is the unit of heat used to express the caloric value of foods and to measure the body’s metabolic rate.
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metabolic rate
The rate at which this heat is produced, the metabolic rate. * The metabolic rate is affected by: exercise, hormones, the nervous system, body temperature, ingestion of food, age, gender, climate, sleep, and nutrition. * Measurement is called the basal metabolic rate (BMR)
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catabolism-heat related
Most of the heat produced by the body comes from the catabolism
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Anabolism
anabolism is the constructive, building-up phase of metabolism. It requires the input of energy to create larger, more complex molecules from smaller ones. Some examples of anabolic processes in the body include: Synthesizing proteins from amino acids Converting glucose into glycogen for storage Producing triglycerides from fatty acids and glycerol Anabolism is the opposite of catabolism, which is the breakdown of complex molecules into simpler ones. Together, anabolism and catabolism make up the overall metabolic balance in the body.
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Proteins functions:
Proteins functions: enzymes, transportation (hemoglobin) or antibodies, clotting factors, hormones, actin and myosin in muscle, and structural components of the body.
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Anabolism-
Anabolism consists of reactions that combine simple substances into more complex molecules.
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Catabolism
Catabolism consists of reactions that break down complex organic compounds into simple ones.
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Lipids
Lipids are organic substances that supply energy for cellular processes and to build structures Lipids include fats, phospholipids, and cholesterol
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triglycerides
The most common dietary lipids are triglycerides. Triglycerides are found in animal and plant-based foods. * Saturated fats are found in foods of animal origin. * Unsaturated fats are found in foods of plant origin. * Cholesterol is found only in foods of animal origin.
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The process of breaking down fatty acids to produce energy
Lipolysis - First, the triglycerides (fats) are broken down into glycerol and fatty acids through a process called lipolysis. Beta-Oxidation - The fatty acids then undergo beta-oxidation in the mitochondria. This involves a series of reactions that progressively break down the fatty acid chains, releasing acetyl-CoA. Acetyl-CoA Entry into Krebs Cycle - The acetyl-CoA produced from beta-oxidation can then enter the Krebs cycle, where it is further broken down to generate ATP through the electron transport chain. in summary the body catabolizes fatty acids to produce acetyl-CoA, which feeds into the Krebs cycle to generate usable energy in the form of ATP
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lipolysis
What is it? The process of breaking down triglycerides (fats) into smaller parts 🧩 Specifically, splitting fat into glycerol and fatty acids πŸ’₯ Who's involved? πŸ•΅οΈ Hormones like: Epinephrine Norepinephrine Cortisol Why does it happen? To produce energy (ATP) πŸ”‹ Help your body use stored fat for fuel πŸš€ How it works: Triglycerides get split apart Fatty acids are converted to acetyl CoA Acetyl CoA enters the Krebs cycle for energy production πŸ’ͺ
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ketone bodies
the liver converts some acetyl CoA molecules into substances known as ketone bodies.
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Proteins
Proteins are polymers made up of amino acids linked together in a specific sequence. They have a wide variety of functions, including serving as enzymes, hormones, antibodies, and structural components. Protein sources can be classified as: Complete proteins - Found in animal-based foods, contain all essential amino acids. Incomplete proteins - Found in plant-based foods, missing one or more essential amino acids.
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During digestion, proteins are broken down into their amino acid components. These amino acids can then be used for:
Tissue growth and repair Energy production through conversion to glucose Synthesis of new proteins
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krebs cycle
is a key metabolic pathway that occurs in the mitochondria of cells. It's an important part of cellular respiration and energy production. The Krebs cycle is a crucial part of the overall process that allows cells to efficiently extract energy from glucose and other nutrients.
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key points about the Krebs cycle:
It is the second stage of glucose metabolism, following glycolysis. In the Krebs cycle, the acetyl group from acetyl-CoA enters and undergoes a series of chemical reactions. These reactions transfer chemical energy to electron carriers like NADH and FADH2. The Krebs cycle also produces some ATP directly, as well as carbon dioxide and water as byproducts. The energy-rich electrons from NADH and FADH2 then feed into the electron transport chain, which is the final stage of cellular respiration.
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electron transport chain
The electron transport chain is the final stage of cellular respiration, and it's a crucial part of the process that allows cells to produce ATP. The electron transport chain is the most efficient way for cells to generate large amounts of ATP from the breakdown of nutrients like glucose.
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key points about the electron transport chain:
It occurs in the mitochondria, right after the Krebs cycle. The electron transport chain is a series of protein complexes and electron carriers that transfer electrons in a controlled manner. As the electrons move through the chain, they release energy that is used to pump protons (H+ ions) across the inner mitochondrial membrane. This creates a proton gradient, which then drives the enzyme ATP synthase to produce the majority of the cell's ATP. The electron transport chain is an aerobic process, meaning it requires oxygen as the final electron acceptor.