What malignancy are patients with coeliac at increased risk of?
Lymphoma
What are the vitamin K-dependent clotting factors?
II, VII, IX & X
What is the eradication therapy for h. pylori infection?
- PPI
- Clarithromycin
- Amoxicillin (metronidazole if allergic)
What are the side effects of amiodarone?
NIPLE
- N = Neuropathy
- I = Iodine, hyper-/hypothyroidism
- P = Pneumonitis
- L = Liver toxicity
- E = Eyes, optic neuritis
What is the treatment regime for TB?
What are the common side effects?
RIPE:
- Rifampicin (Orange secretions)
- Isoniazid (Peripheral neuropathy)
- Pyrazinamide (sideroblastic anaemia)
- Ethambutol (Optic neuritis leading to red green colour blindness)
RIP = hepatotoxic
What is the common genetic defect seen in akylosing spondylitis?
HLA-B27
What viruses are commonly involved in pericarditis?
Coxsackie B
What is Dressler’s syndrome? How is it treated?
Pericarditis 2-3 weeks post-MI
Due to autoimmune inflammatory reaction to myocardial antigen
Treated with colchicine
What must all pts starting isoniazid be given?
Pyridoxine (vitamin B6)
Prevents peripheral neuropathy
What should you give any patient who has a history of alcohol abuse and requires IV glucose?
IV pabrinex
Thiamine (vit B1) is essential for carbohydrate metabolism and a sudden load can exhaust thiamine levels
What is the mechanism of action of transexamic acid?
Inhibits fibrin degradation
