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Flashcards in Reabsorption In The Kidney Deck (11):
1

How can you decribe reabsoprtion in the PCT?

Isosmotic, so that the ECF has the same osmotic pressure

2

How is sodium reabosrbed in the PCT?

Na+ is pumped across the basolateral membrane by 3Na+- 2K+ ATPase, Na+ moves across the luminal membrane down its conentration gradient using a membrane transporter or channel and water follows

3

What are the sodium transporters found in the PCT?

Na-H antiporter, and a Na-glucose symporter

4

What are the sodium transporters found in the loop of henle?

Na-K-2Cl symporter

5

What are the sodium transporters found in the early DT?

Na-Cl symporter

6

What are the sodium transporters found in the late DT and CD?

ENaC and RomK

7

What does SGLUT transport?

Two Na+ ions + 1 glucose agaisnt the concentration gradinet

8

What are some of the substances secreted in the tubule fluid?

Protons, potassium and organic anions and cations

9

How would you estimate the glomeluar filtration rate?

GFR= (concentration in urine x volume in urine)/plasma concentration

10

What is eGFR used for?

To estimate the creatinine clearnace

11

How would you determine eGFR?

(140-age)x mass in kgxconstant(1.23)/serum creatinine