Flashcards in Reabsorption In The Kidney Deck (11)
How can you decribe reabsoprtion in the PCT?
Isosmotic, so that the ECF has the same osmotic pressure
How is sodium reabosrbed in the PCT?
Na+ is pumped across the basolateral membrane by 3Na+- 2K+ ATPase, Na+ moves across the luminal membrane down its conentration gradient using a membrane transporter or channel and water follows
What are the sodium transporters found in the PCT?
Na-H antiporter, and a Na-glucose symporter
What are the sodium transporters found in the loop of henle?
What are the sodium transporters found in the early DT?
What are the sodium transporters found in the late DT and CD?
ENaC and RomK
What does SGLUT transport?
Two Na+ ions + 1 glucose agaisnt the concentration gradinet
What are some of the substances secreted in the tubule fluid?
Protons, potassium and organic anions and cations
How would you estimate the glomeluar filtration rate?
GFR= (concentration in urine x volume in urine)/plasma concentration
What is eGFR used for?
To estimate the creatinine clearnace