[RECALLS] Ig and Porphyrin - Batch 2022 Flashcards

1
Q

Bilirubin found on bile ductules

A

Bilirubin diglucoronides

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2
Q

Direct measurement of CO

A

Heme oxygenase

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3
Q

Ferroxidase activity

A

Ceruloplasmin or haphaestin

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4
Q

Exhibits polymorphism except

A

Ferritin

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5
Q

Total protein in human plasma (g/dL)

A

7.0 - 7.5

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6
Q

Characterized by profound neurologic impairments

A

Zellweger syndrome

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7
Q

Rapid formation and reshuffling of disulfide bonds

A

PDI

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8
Q

Ubiquitin

A

4

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9
Q

Sugar in nucleotide

A

Pentose

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10
Q

Colorless

A

Urobilinogen

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11
Q

Ig is kappa or lambda, never mixed:

A

True

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12
Q

5 phosphoryl group esterify 2nd hydroxyl group

A

Phosphodiester

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13
Q

Phosphoryl group linked to the phosphoryl group of a mononucleotide

A

Acid anhydride bond

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14
Q

From the mitochondria, outer membrane receptor

A

TOM 20./22

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15
Q

Proteins are transferred to this neighboring import channel

A

TOM 40

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16
Q

Repository of heme

A

RBC

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17
Q

Important element in body cause seen in hemoprotein

A

Iron

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18
Q

From apical surface to interior

A

DMT1

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19
Q

Ferric to ferrous

A

Ferrireductase

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20
Q

Bidirectional movement along nucleus and cytoplasm

A

Ran protein

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21
Q

True about signal peptide

A

At least 1 positive charge etc

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22
Q

Primary immune response

23
Q

Nucleoside

24
Q

Main antibody in secondary response. Opsomizes bacteria

25
Found on surfaces of B cells as a receptor for antigen
IgD
26
Function of Ig other than direct binding of antigen
Fc
27
Physiologic functions of nucleotides except
Energy metabolism
28
True of bilirubin except
Bound to albumin thru non covalent forces increases plasma solubility
29
Hydrostatic pressure of arterioles
``` 37 mmHg (Book) 40 mmHg (ppt) ```
30
Involved in intra-GA transport & retrograde transport from the GA to the ER
COP I
31
Involved in export from the ER to either ERGIC or the GA
COP II
32
Transport in post-GA locations including the PM, TGN and endosomes
Clathrin
33
Regulated secretion from organs such as the pancreas
Secretory vesicles
34
Carry proteins to the PM & are also involved in constitutive secretion
Vesicles from the TGN to the PM
35
Low PO2 in peripheral tissues causes synthesis of:
2,3 - BPG
36
Direct measurement of CO
Heme oxygenase
37
Colourless compound
Urobilinogen
38
Colored compound found in feces
Stercobilin
39
Porphyrin ring
Hydrophobic
40
Blue-green color
Biliverdin
41
What happens to albumin when removed from bilirubin
Remains in plasma
42
Location of heme oxygenase
Endoplasmic reticulum
43
Conjugation of bile is catalyzed by
UDP-Glucoronyl transferase
44
Has large capacity that even under the pathologic conditions, transport does not appear to be rate-limiting for metabolism of bilirubin
Facilitated transport system
45
Derivatives of purine and pyrimidine that has a sugar-linked to a ring N
Nucleosides
46
Sugar is linked to a heterocyclic base via
B.N-glycosidic bond
47
True of a sugar that is linked to heterocyclic base
Pyrimidine at N1 ; purine at N9
48
Nucleoside with a phosphoryl group esterified to OH group of sugar
Mononucleotide
49
Free nucleotides
Xanthine Hypoxanthine Uric acid
50
Function of purines and pyrimidines
High group transfer potential
51
Nucleoside derivative of guanine
Guanosine
52
True about P50 except:
PO2 half saturates myoglobin
53
5' end on the
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