[RECALLS] Plasma Proteins And Ig; Purine And Pyrimidine Biosynthesis Flashcards

(30 cards)

1
Q

Attaches on surface of mast cells

A

IgE

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2
Q

Active during allergic response

A

IgE

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3
Q

Most abundant plasma protein

A

Albumin

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4
Q

Binds to ffa, calcium, some copper and bilirubin

A

Albumin

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5
Q

Both monomer and dimer

A

IgA

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6
Q

Low levels during hemolytic anemia

A

Haptoglobin

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7
Q

Transports iron to where it is needed

A

Transferrin

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8
Q

Carries iron across basolateral membrane

A

Ferroportin

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9
Q

Main copper transporter in plasma

A

Ceruloplasmin

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10
Q

Mutated copper binding p-type atpase in wilsons disease

A

ATP7B

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11
Q

Found in secretions

A

IgA

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12
Q

Ig mainly for secondary immune response

A

IgG

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13
Q

Ig mainly for primary immune response

A

IgM

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14
Q

This is found in the surface of B cell that binds to antigen

A

IgD

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15
Q

Separation technique where proteins migrate to one side

A

Electrophoresis

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16
Q

Plasma protein that migrates to gamma region during electrophoresis

A

Immunoglobulins

17
Q

Mitochondrial enzyme

A

Carbamoyl phosphate synthase I

18
Q

Which one is not a multifunctional enzyme

A

PRPP Glutamyl amidotransferase

19
Q

Treatment for acute gout

20
Q

Deficiency in Von Gierke’s

A

Glucose 6 phosphate

21
Q

Which is true about purine biosynthesis

A

Phosphoribosyl pyrophosphate- 1st intermediate in denovo pathway

22
Q

Major determinant of overall rate

A

PRPP pool size

23
Q

1st product in pyrimidine is recycled to form

A

Cytidine and uridine

24
Q

First pyrimidine formed

25
All synthesized in the liver except
Gamma globulin
26
Preferred locus target for gout
Xanthine oxidase
27
Lesch nyhan syndrome
HGPRT deficiency
28
ADA deficiency results in accumulation of
Deoxyadenosine and adenosine
29
Parent nucleotide of AMP and GMP
IMP
30
Non-multifunctional purine enzyme catalyzed
Reaction 5