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Flashcards in Renal Disorders II Deck (38)
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31

Acute post-streptococcal GN: presentation

- acute nephritic syndrome
- kidney injury
- Hypertension
- Low Complement 3 levels
- ASO titer serially elevated

32

Key features of acute post-streptococcal GN

- diffuse endocapillary proliferative GN with subepithelial "humps"
- IgG and C3 deposits by immunofluorescence

33

Proliferative lupus nephritis

- acute nephritic syndrome
- systemic symptoms of active lupus: arthritis, rashes

34

Proliferative lupus nephritis evidence

- serology: anti nuclear antibody, anti-dsDNA+, low complements C3 and C4

35

Key features of lupus nephritis

- endocapillary proliferation, crescents, necrosis
- FULL house pattern by immunofluorescence
- subendothelial deposits

36

Three types of hypercellularity

- mesangial
- endocapillary
- crescents

37

Causes of acute nephritic syndrome

1. crescentic GN (3 types)
2. diffuse proliferative GN (2 types)

38

Types of nephritic syndrome

- isolated hematuria
- acute nephritic syndrome