renal/reproductive Flashcards

(64 cards)

1
Q

what is type of nephron are the majority

A

cortical

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2
Q

what type of nephron are the minority

A

juxtamedullary

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3
Q

function of glomerular capillaries

A

where filtration of blood occurs

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4
Q

function of peritubular capillaries

A

carry away substances reabsorbed from filtrate

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5
Q

what is the filtration fraction

A

20% of plasma

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6
Q

how many liters of filtrate are reabsorbed in a day

A

180 L/day

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7
Q

what do the fenestrations of the glomerular endothelial cell do

A

prevents filtration of blood cells

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8
Q

what does the basal lamina of glomerulus do

A

prevents filtration of larger proteins

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9
Q

what doe slit membrane between pedicels do

A

prevents filtration of medium sized proteins

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10
Q

what are the 2 mechanisms of autoregulation of the GFR

A

myogenic and tubuloglomerular feedback

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11
Q

what is the myogenic mechanism

A

when blood pressure stretches’ the afferent arteriole, smooth muscle contractions reduce the diameter

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12
Q

what is the tubuloglomerular feedback

A

high bp causes Na and Cl not to be reabsorbed, macula densa detects this,, inhbits nitric oxide, afferent arterioles constrict, reduce gfr

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13
Q

with moderate sympathetic stimulation what happens to gfr

A

decreases slightly

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14
Q

what happens to gfr with extreme sympathetic stimualtion

A

decreases substantially

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15
Q

what are the two hormones that contribute to the regulation of the GFR

A

ANP and angiotensin II

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16
Q

what does anp do

A

increases gfr

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17
Q

what does angiotensin ii do

A

reduces gfr by vasoconstriction

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18
Q

what is the concentration of fluid in the renal corpuscle

A

300 mOsm/liter, isotonic to blood

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19
Q

what part of the renal tubule does the most reabsorption

A

the proximal convoluted tubule

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20
Q

what is secreted during tubular secretion

A

H+ and NH4+, creatine, K+

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21
Q

what is paracellular reabsorption

A

when solutes move between cells

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22
Q

what is transcellular reabsorption

A

when solutes move through the apical and basal membranes

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23
Q

what is obligatory water reabsorption

A

when water is following solutes through diffusion

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24
Q

what is facultative water reabsorption

A

water moves in collecting duct due to ADH

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25
what do Na+ symporters help reabsorb in the PCT
glucose, amino acids, lactic acids, water soluable vitamins
26
what is the renal threshold of glucose
200 mg/dL
27
what is the concentration of blood at the end of the PCT
300 mOsm/L
28
what is the concentration of blood at the end of the loop of henle
100-150 mOsm/L
29
what are the two types of cells in the DCT and collecting duct
principal and intercalated cells
30
what do principal cells do
reabsorb sodium and secrete potassium
31
what do intercalated cells
reabsorb potassium and bicarb and screte h+
32
what does ADH do to make concentrated urine
stimulates symporters in thick limb of ascending loop of henle, facultative water reabsorption, urea cycling
33
what is countercurrent multiplication
a process that increases the osmotic gradient in the if of the renal medulla
34
what is countercurrent exchange
process that allows solvents to be reabsorbed into blood and O2 delivery to cells
35
what is the descending loop of henle permeable to
permeable to water but impermeable to solutes
36
what is the ascending limb of loop of henle permeable to
impermeable to water but permeable to solutes
37
late dct and collecting duct what is it permeable to
water only in the presense of ADH
38
what are the three sex glands in males
seminal vesicles, prostate, and bulbourethral gland
39
what do sertoli cells do
nurse cells, support sperm production,
40
what do leydig cells do
testosterone producers
41
what is spermiation
release of mature spermatozoa from sertoli cells
42
what is capacitation
final maturation of sperm in the uterine tract
43
What does LH do in males
stimulates test prod by leydig cells
44
what does FSH do in males
acts on sertoli cells to promote spermatogenesis
45
what hormone does a follicle release
estradiol
46
what is the stratum functionalis
shed during menstration
47
what is the stratum basalis
replaces stratum functionalis each uterine cycle
48
what is the secretory phase of the uterine cycle
endometrial glands secrete special mucus in repsonse to progesterone and estrogen to prepare for pregnancy
49
what happens in the uterus during menstrural phase
declining levels of progesterone cause an end to menstration, stratum functionalis layer sloughed off
50
what happens in the ovary during the menstrual phase
the follicles begin secreting estrogen, fluid is fillin antrum
51
what happens in ovary during preovulatory phase
follicular secretion of estrogen and inhibin slowed down secretion of FSH, increasing levels of estrogen trigger LH
52
what happens in the uterus during the preovulatory phase
increasing estrogen levels have repaired the stratum functionalis
53
what hormonal changes happen during ovulation
high levels of estrogen from mature follicles stimulate release of LH and gnrh, LH surge brings ovulation
54
what happens in the ovary during the postovulatory stage
if fertilazation doesnt occur, corpus albicans is formed, if it does, embryo secretes hCG
55
happens in the uterus during the postovulatory
hormones from courpus luteum promote thickening of endometrium
56
what does fsh do in females
growth of follicles that secrete estrogen
57
what does LH do in females
stimulates ovulation and formation of corpus luteum
58
what does progesterone do
prepares uterus for implantation and mammary gland for milk secretion
59
what does relaxin do
facilitates implantation in the relaxed uterus
60
what does inhibin do
inhibits secretion of FSH
61
how long is the germinal stage
first two weeks after fertilization
62
how long is the embryonic stage
weeks 3 thru 8
63
what is the stages of development in the germinal stage
zygote, morula, blastocyst
64
what is the blastocyst called after implantation
embryo