Respiratory/Immune Flashcards

(63 cards)

1
Q

what is external respiration

A

the exchange of gases between the atmosphere and blood

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2
Q

what is internal respiration

A

gas exchange between capillary blood and the cells in tissue

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3
Q

where does the conducting zone end

A

terminal bronchioles

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4
Q

how many bronchopulmonary segments does the right lung have

A

10

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5
Q

how many bronchopulmonary segments does the left lung have

A

8

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6
Q

what does each terminal bronchiole supply

A

one lung lobule

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7
Q

what type of alveolar cell make up 97% of an alveoli

A

type 1 alveolar cells

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8
Q

what type of alveolar cells make up 3% of an alveoli

A

type 2 alveolar cells

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9
Q

what is nutritional flow

A

when the lung tissue receivesoxygenated blood form the bronchial arteries, which branch off from the aorta

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10
Q

what is pulmonary flow

A

the pulmonary arteries supply the lung capillaries which turn into the pulmonary vein

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11
Q

how does the diaphram help inspiration

A

stretches the thoracic cavity longwise

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12
Q

how do external intercostal muscles help inspiration

A

move ribs up and outward expanding the ribcage

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13
Q

how does the sternoclamatoid muscle help inspiration

A

elevates the sternum

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14
Q

how do the scalenes help inspiration

A

elevate the top two ribs

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15
Q

how do the internal intercostal muscles help expiration

A

muscles pull ribs downward & inward, reducing the diameter of the rib cage

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16
Q

how do abdominal muscles help expiration

A

depress the lower ribs and elevate the diaphragm by increasing abdominal pressure

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17
Q

when does inspiration occur

A

when pressure in the lungs becomes lower than the pressure in the atmosphere, P lung < P atmosphere

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18
Q

when does expiration occur

A

occurs when pressure in the lungs is higher than the pressure in the atmosphere, P lung > P atmosphere

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19
Q

what is transpulmonary pressure

A

The pressure difference between the pressure inside the alveoli and the pressure outside the lungs in the pleural cavity

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20
Q

what are the 2 ways that O2 is transported in the blood

A

dissolved in the plasma and bound to hemoglobin

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21
Q

what is a Bohr shift

A

a shift in the oxy-hemo curve to right, due to low blood ph, increased blood PCO2, and increased temperature

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22
Q

what is hypoxia

A

inadequate oxygen at the tissue level

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23
Q

what is anemia

A

lowered ability of blood to carry oxygen because of low hemoglobin

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24
Q

what is hypoxemia

A

low blood O2 due to low hemoglobin saturation

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25
what are the three methods of CO2 transportation
in plasma as bicarbonate ions, bound to hemoglobin as carbaminohemoglobin, disolved in plasma
26
what is the name of the group of inspiratory neurons
DRG, dorsal respiratory group
27
what is the name of the group of expiratory neurons
VRG, ventral respiratory group
28
Are the expiratory neurons active during rest
no
29
what are the two centers of the pontine respiratory group
apneuistic center, and pnuemotaxic center
30
what does the apneuistic center do
stimulates the DRG
31
what does the pnuemotaxic center do
fine tunes breathing, inhibits DRG
32
What do pulomary stretch receptors respond to
responds when bronchioles are inflated or stretched
33
What do central Chemoreceptors respond to
low pH and high CO2 in CSF in brain
34
what do peripheral chemoreceptors respond to
respond to low O2 levels in blood
35
what are the primary lymphatic organs
red bone marrow and thymus
36
what are lymph nodes
small swellings where lymph if filtered, found at irregular intervals
37
what is innate immunity
the body's first line of defense, non specific
38
what are physical barriers
skin, mucous membranes, hairs and cilia, acid, tears
39
what is a fever
when the body's thermostat is set upwards in repsonse to a pyrogen
40
what si inflammation
the bodily repsonse to when tissues are damaged
41
what are the 4 signs of acute inflammation
redness, heat,swelling, and pain
42
what are the three phagocytic white blood cells
neutrophils, eosionophil, monocyte
43
what are natural killer cells
special class of T cells which perform generalized functions such as kill tumor cells and infected cells
44
how to NKC kill
by cytolysis, they secrete perforin
45
what are the two antimicrobial proteins
interferons and complement proteins
46
how do interferons work
virus infected cells release interferons which bind to a non infected cell causing the release of anti viral proteins
47
what do complement proteins do
Form MAC attacks that punch holes in the membrane of intruders
48
what is one feature about adaptive immunity
tolerance for self proteins and specificity for particular foreign molecules
49
what is another feature about adaptive immunity
memory of past foreign molecules
50
where do b cells mature
in bone marrow
51
where do t cells mature
thymus
52
how many amino acids in a sequence are needed to distinguish bacteria from human protein
8
53
what are residual bodies
the remnants of a pathogen after a phagocyte has eaten them
54
what are MHC proteins
they display antigens to the immune system
55
what kind of antigen does MHC 2 protein present
extracellular, proteins digested by phagocytes
56
what kind of cell interacts with the antigen found on MHC 2 proteins
helper t cells
57
what kind of antigen does MHC 1 present
intracellular proteins by random sampling
58
what kind of cell interacts with the antigen presented MHC 1 proteins
cytotoxic t cells
59
what kind of cells present antigen with the MHC 1 protein
all nucleated cells
60
what is the the only kind of cell that can interact with MHC 1 proteins
T CELL
61
helper t cells are aka
CD4
62
cytotoxic t cells are aka
CD8
63
a complete antigen has which two properties
immunogenicity and reactivity