repro 3 Flashcards

(54 cards)

1
Q

mifepristone is given with what drug

A

misoprotol

mifepristone is a progeterone antagonist

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2
Q

bicornuate uterus

A

failure of fusion of paramesonephric ducts

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3
Q

two major causes of third semester bleeding

A

placenta previa and abruptio placenta

placenta previa presents as PAINLESS bleeding and no distress for fetus

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4
Q

first line PCOS treatment for PCOS patiets williong to conceive

A

climiphene
GnRH agonist
induce ovulation

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5
Q

27 year Oldman history of travel to carribean
2 day history of tender ulcerated lymphadenopathy
initially had a painless ulcer that resolved on its own

A

lymphgranulosa verosum chlamydia L1 L3
txt doxy
pregnant txt: azithromycin

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6
Q

DD sypillis and lymphogranuloma vereneum

A

both are painless ulcers BUT

syphilis has NO LOCAL LYMPHADENOPATHY

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7
Q

risk factors for endometrial cancer

A
think anything that increases estrogen exposure
obesity 
estrogen only pills
nulliparity
early menarche
late menopause
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8
Q

histological exam of tissue resected during a hysterectomy
transitional epithelium can be seen
what might have caused this

A

resection of uretes while cutting the broad ligament

ureter and bladder are lined with transitional cells

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9
Q

epispadias is caused by abnormal development of?

and which structure does this give rise to in females

A

genital tubercle

glans clitoris

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10
Q

abnormal development of urogenital folds gives rise to?

A

hypospadias in men

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11
Q

epispadias can be associated with

A

bladder and bowel extrophy

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12
Q

what is the major complication of preeclampsia and how is it tested

A

DIC

d dimer test (fibrin split products)

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13
Q

pt has no uterus what are the differentials

A

Mullerian agenesis
androgen insensitivity syndrome
5 alpha reductase def

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14
Q

DD Mullerian agenesis and Androgen insensitivity syndrom

A

AISD…. XY and testes present

Mullerian is a normal female just no paramesonephric duct

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15
Q

weil felix reaction tests for which infection

A

ricketssial

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16
Q

hypoacusis vs hyperacusis

A

hypo— cant hear low sounds

hyper—cant resist loud noises

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17
Q

hypoacusis causes vs hyperacusis causes

A

hypo — damage to trigeminal nerve V3 mandibular branch….. tensor tympani muscle

hyper —- damage to sapes muscle supplied by cranial nerve 7 facial nerve…

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18
Q

pharyngeal arch 1 derivatives

A

MATT
mylohyoid,anterior digastric, tensor tympanii, tensor veli palatine
innervation by trigeminal nerve

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19
Q

define gummas in tertiary syphillis

A

subcutaneous granulomas

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20
Q

secondary syphilis signs

A

4 10 weeks

maculopapular rash, condyloma lata, lymphadenopathy, hair loss, muscle pain, fever

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21
Q

spina bifida problem occurs during which week of gestation

A

4th week

this is when the posterior neuropore closes

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22
Q

describe histology of the pagets disease

A

eczematous patch often with underlying DCIS
large cells with prominent nucleoli and clear halos
risk factors: nulliparity early menarche late menopause obesity

23
Q

histo of breast extracellular mucus surrounding the tumor cells

A

mucinous carcinoma is a rare form of DCIS

originates in milk duct

24
Q

fibrovascular structures lined by ductal epithelim (BREAST)

A

intraductal papilloma

no scaly rash like DCIS

25
infant has hypoglycemia, hepatomegaly and lactic acidosis | what enzyme is at fault
glucose 6 phosphatase | this enzyme is required for the final step of gluconeogenesis and glycogenolysis
26
alpha 1,4 glucosidase def
pompe disease | hypertrophic CM, cardiomegaly, hypotonia
27
alpha 1,6 glucosidase
cori disease
28
wht keeps a penis erect
parasympathetic S2 S4
29
acute prostatitis causes <35 years and >35 years
<35.... chlamydia and gonorrhea | >35..... ecoli pseudomonas and klebsiella
30
what test can be performed to check for genetic mutations for example parents wanting to find out if the child will have CF
polymerase chain reaction and sequencing
31
which tanner stage is this | downy pubic hair and formation of breast bud
tanner 2 | first signs of puberty
32
dark thick pubic hair and enlarged breasts | growth spurt
tanner 3
33
how to separate tanner 3 from tanner 4
tanner 4 has raised areola
34
positive nitrite test and bacteria grown with eosin methylin blue agar
Ecoli
35
bacteria grown on bile esculin agar | negative nitrite test for UTI
enterococcus
36
treatment of skin infection caught by yoga mats | pt complains of skin hyperpigmentation after using the tretment
ketoconazole MOA --- blocking formation of fungal membrane steroids ALSO blocks desmolase and 17 a hydroxylase 17 a hydroxylase block ----- responsible for the antiandrogenic effects (libido,gynecomastia) desmolase ----- desmolase is essential for adrenal cortisol production which is used for feedback inhibiton of POMC gene which codes for ACTH and melanocyte stim hormone
37
which antifungal druga has good CNS penetration and can be used for Cryptococcus neofrom
flucytosine | flucanozole
38
production of which hormone would indicate sex of baby on ultrasound
dihydroesterone | external genatalia
39
pt has suprapubic abd tenderness dysuria polyuria prev 3 vaginal births diagnosis and complication
uterine prolapse | pyelonephritis.... cardinal ligaments may compress the ureters and cause hydronephrosis
40
cancer in prostate | specimen must be taken from which part
peripheral zone
41
clomiphene mechanism
inhibits estrogen | leads to positive feedback
42
medication commonly used for seizure prophylaxis in pregnant patients with preeclmpsia
Magnesium is used to treat preeclampsia, which presents with hypertension and proteinuria in the last 10 weeks of pregnancy. Magnesium toxicity results in loss of deep tendon reflexes, sinoatrial and atrioventricular node blockade, drowsiness, respiratory depression, and ultimately cardiac arrest.
43
what runs on top of spermatic cord
ilioingunial nerve damage can cause loss of sensation on medial thigh and scrotum L1
44
which nerve is resp for cremeteric reflex
genitofemoral nerve
45
female with G6PD ... what is the mechanism of disease transfer
lyonization This is the process by which one part of the X chromosome is inactivated (heterochromatin) and the other corresponding part of the second X chromosome is activated (euchromatin). If the activated portion of the second chromosome contains mutant DNA, then X-linked recessive diseases can present.
46
during which stage is chlamydia infectious
Elementary body extracellular
47
what develops into prostate
urogenital sinsu
48
neonatal chorioretinitis
toxoplasmosis
49
neonatal conjunctivitis on day 15 what is the pathogen and what can be the other condition caused by it
chlamydia | pneumonia
50
how can you diagnose chlamydia pneumonia in a neonaet
CBC will show eosinophilia
51
oocytes are arrested in which stage after ovulation
metaphase II
52
is early pregnancy a srisk factor for breast cancer
NO | late pregnancy is
53
patient’s serum α-fetoprotein (AFP), unconjugated estriol, and β-human chorionic gonadotropin (β-hCG) levels are all low. The inhibin A concentration is normal.
edwards trisomy 18
54
a thyroid secreting ovarian teratoma
struma ovarii