Reproduction and Endocrine Flashcards Preview

Year 1 NSF > Reproduction and Endocrine > Flashcards

Flashcards in Reproduction and Endocrine Deck (73)
Loading flashcards...
1

What is oogenesis?

The formation of gametes in the ovaries

2

How are oogonia developed?

In foetal development, primordial cells migrate from yolk sax to ovaries where they differentiate into oogonia

3

What do some oogonia develop into?

Primary oocytes and enter prophase of meiosis 1

4

What happens at puberty?

Several primordial follicles stimulated each month, follicles develop to tertiary follicle, and oocytes to secondary oocyte

5

How many chromosomes does a secondary oocyte have?

Haploid (half)

6

What occurs at ovulation?

tertiary follicle ruptures to expel secondary oocyte

7

When does the second meiotic occur?

After fertilisation

8

What happens to the follicle after it ruptures?

It becomes a corpus luteum

9

What happens to a corpus luteum if secondary oocyte not fertilised?

After 14 days undergoes luteolysis, stops secreting progesterone and becomes corpus albicans

10

How is the anterior and posterior developed?

Anterior- made from endocrine cells from rathkes pouch which wraps around the posterior
Posterior- Extension of hypothalamus into anterior

11

What controls the release of anterior pituitary hormones?

Neurohormones from hypothalamus via a portal system

12

What kind of hormones does hypothalamus release which causes anterior to produce what hormones?

Hypothalamus- releasing hormone
Anterior- trophic hormone

13

What 6 hormones does the anterior pituitary secrete?

FLAT PiG
FSH
LH
ACTH
TSH
Prolactin
GH

14

What is multi-loop feedback in hypothalamus and anterior pituitary?

There is a short loop and long loop, which tropic inhibits releasing as well as hormone

15

What is the structure between anterior and posterior pituitary called?

Intermediate lobe

16

Where is GnRH released from?

The hypothalamus

17

What does GnRH cause the release of?

FSH and LH

18

What does FSH do?

stimulates growth and recruitment of mature follicles

19

What are the functions of LH?

Produces precursors for oestrogen production
Maintains corpus luteum
Stimulates- maturation, ovulation, luteinisation

20

What do developing follicles and corpus luteum produce after stimulation from FSH and LH?

Follicles- Inhibin/oestrogen
CL- Progesterone

21

Why are developing follicles and corpus luteums transient endocrine glands?

They come and go

22

What does progesterone inhibit?

LH and GnRH

23

What does oestrogen start by inhibiting?

LH and GnRH

24

What does inhibin inhibit?

FSH

25

Why does oestrogen change to positive feedback?

The sensitivity of brain changes in the late follicular phase

26

What is a dominant follicle?

A tertiary follicle that produces lots of oestrogen preventing other follicles maturing

27

What happens after the follicular phase?

Oestrogen causes GnRH which causes LH to produce (FSH inhibited by inhibin) increasing oestrogen and so on until ovulation

28

What causes ovulation?

An LH surge from positive feedback

29

What follows the follicular phase?

Luteal phase

30

What is oestrus?

Sexually receptive to the male