Reproductive Flashcards
Lens dislocation seen where? Positions?
Homocysteinuria - infero-nasal
Marfan’s - supero-temporal
Enzyme converting testosterone to DHT
5 £ reductase
Most common precursor of choriocarcinoma?
Characterisic appearance?
Hydatidiform Mole
‘cluster of grapes’ or ‘honeycomb uteus’
Most common gynecologic malignancy
Prognosis?
Cervical cancer (worldwide) Endometrial carcinoma (US) Peak @ 55-65
Worst prognosis: ovarian > cervical > endometrial
Most common of all tumors in females?
Progression to malignancy?
Characteristic appearance?
Leiomyoma (fibroid)
- Estrogen sensitive
- 20-40 years old
- Do not progress to Leiomyosarcoma
Whorled pattern with smooth muscle bundles
Most common ovarian mass in young women
Follicular ovarian cysts
Where do you find Schiller Duval bodies
Yolc sac ( Endodermal sinus) tumor
Characteristic feature of Yolkc sac Endodermal sinus tumor resembling glomeruli
Schiller Duval Bodies
Most common (90%) ovarian germ cell tumor
Benign? Malignant?
Mature Teratoma
Benign
Characteristic bodies in Serous cystadenocarcinoma
Psammoma bodies
What gynecologic pathology do you see Pseudomyxoma peritonei?
Mucinous Cystadenocarcinoma (ovarian non germ cell tumor)
Meig’s Syndrome
Ovarian Fibroma
Ascites
Hydrothorax
Call Exner Bodies
Granulosa Cell Tumor
Characteristic feature of Granulosa Cell Tumor
Call Exner Bodies
- small follicles filled with eosinophilic secretions
Mucin-secreting Signet Cell Adenocarcinoma
Krukenberg Tumor
- GI malignancy that metastasizes to ovaries
Single most important prognostic factor in breast malignancy
Axillary LN involvemment
Most common (76%) of all breast CA
Invasive Ductal Breast CA
worst prognosis
Most invasive
Breast CA with characteristic ‘Indian file’ order of cells
Invasive Lobular Breast CA
Causes of Gynecomastia
Klinefelter's syndrome Drugs: estrogen, marijuana, heroin, psychoactive Spirinolactone Digoxin Cimetidine Alcohol Ketoconazole
Prostate CA location
Posterior lobe (Peripheral zone) of Prostate gland
Drugs for BPH
£1 antagonists ( terazosin, tamaulosin)
5-£ reductase inhibitor (Finasteride)
Most common (~95%) of all testicular tumor
Seminoma painless 'fried egg' appearance high Placental Alk Phisphatase (PLAP) excellent prognosis
Most common testicular tumor among elderly men (over age of 60)
Testicular Lymphoma
agressive Non hodgkin Lymphomas
Peynoire’s Disease
Bent penis due to acquired fibrous tissue formation (fibromatosis of the Buck’s fascia)
