Reproductive Hormones

Question 1

Androgens/Anabolic Steroids: what is it? use, controlled? administration

Answer 1

Male sex hormones

Promote muscle growth in beef cattle

Controlled, but implants sold OTC

Long acting implants, mixed with female hormones to prevent abuse

Question 2

Progesterone: what is it? uses (2), caution

Answer 2

Type of female sex hormones, produced after ovulation by the corpus luteum

Depending on species and circumstance: suppress or sync estrus

People who are pregnant or have certain medical conditions should avoid/use with caution

Question 3

Altrenogest: brand name, effect/use, administration

Answer 3

Regu-Mate

Suppress/Sync estrus in horses

PO via syringe or on feed

Question 4

Altrenogest: cautions (2)

Answer 4

Can’t use in horses intended for food

PO formula can still be absorbed through skin, typical progesterone cautions

Question 5

Megestrol Acetate: effects (2), uses (SA [2] and LA [2])

Answer 5

Blocks effects of estrogen

Significant glucocorticoid effects

SA: suppress estrus

Last ditch TX for allergic pruritis and behavioral issues I’m cats

LA: Suppress estrus in beef heifers

Improves feed efficiency

Decreases behavioral issues

Question 6

Dinoprost: brand name, what is it? effects (2), uses (3)

Answer 6

Lutalyse

Prostaglandin F2 alpha analog

Causes lysis of the corpus luteum –> reduces progesterone and initials new estrus cycle

Induce abortion

Medical tx of pyometra

Synchronize estrus

Question 7

Clopridtenol: what is it? effects (2), uses (3)

Answer 7

Prostaglandin F2 alpha analog

Causes lysis of the corpus luteum –> reduces progesterone and initials new estrus cycle

Induce abortion

Medical tx of pyometra

Synchronize estrus

Question 8

Prostaglandin F2 alpha Analogs: cautions (2)

Answer 8

Don’t use in pregnant animals when abortion is not desired

Should NOT be used by people who are pregnant suspect they are pregnant

Question 9

Sucramate: generic name, effect, use, administration, caution

Answer 9

Deslorelin acetate

Stimulates release of luteinizing hormone –> induces ovulation

Induce ovulation in mares: requires a mature follicle

Usual hormone cautions, can disrupt menstrual cycle

Question 10

Suprelorin: generic names, effect, uses, administration

Answer 10

Deslorelin acetate

Inhibits FSH and LH

Treat Adrenal Disease in ferrets

SQ implant in dorsal interscapular space

Not approved by the FDA, may ONLY be used in this form to treat this disease