rheumatoid Flashcards
(42 cards)
if you are thinking about starting DMARDs (hydroxychloroquine or azathrioprine (imuran) on a pt w/ RA, what exam must be done first?
Eye
both can cause retinitis
Is reactive arthritis an HLA-B27 disorder or associated with a post GI/GU infection?
Both
treatment of reactive HLA-B27?
NSAIDS
are HLA-B27 disorders RF positive or negative?
negative
factors of psoriatic arthritis?
pitting nails, psoriasis, uvetitis/conjunctivitis, arthritis (SI and DIP)
tx of psoriatic arthritis?
NSAIDS or sulfasalazine
what lab is 99% positive in lupus?
ANA, double stranded DNA is also highly positive
Name the rash associated with lupus
discoid/butterfly/malar
Is ANA + or - in raynauds?
negative
Is ESR high or low in raynauds?
normal
explain scleroderma?
multi-system autoimmune, deposition of collagen
What syndrome describes the characteristics of scleroderma?
CREST, calcinosis, raynauds, esophageal dysmotility , sclerodactyly-chronic contractures & Telangiectasis
what lab is 95% positive is scleroderma?
ANA
age group & gender affected by scleroderma?
female 30-50
tx for scleroderma
symptomatic
sjogren’s pt are 40x higher risk of what medical condition?
lymphoma
ok
ok
characteristics of scleroderma?
dry eyes, dry mouth, and enlarged saliva glands
describe polymyositis
inflammatory muscle disease associated with proximal muscle weakness
patient is having difficulty raising from chair and brushing her hair, you are concerned about polymyositis, what test can be done?
do a striated muscle biopsy. muscle enzymes may be elevated
rash associated with polymyositis?
heliotrope
stiffness after rest and proximal muscle weakness….think?
polymyositis
20 year old male complains of 3 days hx of joint pain that moves around & experiencing redness & swelling over tendon and knee joint. He also has necrotic pustules over fingers.. he has?
gonococcal septic arthritis
how do gonococcal and septic arthritis present differently?
gonococcal migrates from joint to joint, septic affects one joint