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Flashcards in Rheumatology Deck (31):
0

What is a vasculitis that attacks the coronary arteries in young children

Kawasaki disease

1

Vasculitis that affects visceral arteries and can present with abdominal pain

Polyarteritis nodosa

2

Vasculitis that presents as recurrent asthma attacks

Chung-Strauss

3

Vasculitis that presents as recurrent sinusitis, dyspnea' and/or hemoptysis

Wegener granulomatosis

4

Vasculitis that presents with new onset HA, scalp tenderness, and jaw claudication

Temporal arteritis

5

Vasculitis that affects large vessels and may cause syncope

Takayasu Arteritis

6

PE signs with vasculitis

Palpable purpura that don't blanch
Red to purple in color

7

Other causes of palpable purpura

Disseminated meningococcal or gonococcal
Rocky Mountain spotted fever

8

Hallmark lab finding of churg Strauss

Eosinophilia

9

C-ANCA positive is diagnostic for what

Wegners granulomatosis

10

P-ANCA positive is seen in what vasculitis

Microscopic polyangitis
Churg-Strauss

11

Definitive test to document inflammation and destruction of vessels

Biopsy

12

Mainstay of tx for wegners granulomatosis, microscopic polyangitis, polyarteritis nodosa

Prednisone and cyclophosphamide

13

Tx for temporal arteritis and churg Strauss

Prednisone

14

Peak age of RA

40-50

15

Gender more at risk for RA

Female

16

What causes RA

Synovial T cells become activated and synovial lining becomes invasive causing erosion and destruction of joint cartilage

17

High levels of what factors in RA synovial fluid

Tumor necrosis factor alpha
Interleukin-1

18

Key feature with RA

Morning stiffness >1 hour

19

RA deformity at the PIP

Boutonnière deformity

20

RA deformity at the DIP

Swan neck deformity

21

Most commonly affected joints with RA

Proximal inter phalangeal
mCP
Wrist

22

What is the syndrome with splenomegaly, RA, leukopenia

felty syndrome

23

Presents with GU or GI dz and asymmetric lower extremity arthritis

Reactive arthritis

24

Presents with monoarticular knee arthritis with preceding rash and fever

Lyme disease

25

Lab tests for RA

RF
Anti-CCP
Plain films of hands

26

What is used as a bridge for RA when waiting for DMARDs to kick in

Corticosteroids

27

Most common DMARD and adrs

Methotrexate- bone marrow toxicity, hepatic fibrosis, pneumonitis' stomatitis

28

Pyrmidine synthesis inhibitior used for RA. Adrs include diarrhea and rash

Leflunomide

29

Extra-articular manifestations of RA

Rheumatoid nodules
Pleural effusions
Vasculitis
Felty syndrome

30

Associated conditions with RA

Atlantoaxial subluxation
Baker cyst