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Flashcards in Rheumatology Deck (31)
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0
Q

Vasculitis that affects visceral arteries and can present with abdominal pain

A

Polyarteritis nodosa

1
Q

What is a vasculitis that attacks the coronary arteries in young children

A

Kawasaki disease

2
Q

Vasculitis that presents as recurrent asthma attacks

A

Chung-Strauss

3
Q

Vasculitis that presents as recurrent sinusitis, dyspnea’ and/or hemoptysis

A

Wegener granulomatosis

4
Q

Vasculitis that presents with new onset HA, scalp tenderness, and jaw claudication

A

Temporal arteritis

5
Q

Vasculitis that affects large vessels and may cause syncope

A

Takayasu Arteritis

6
Q

PE signs with vasculitis

A

Palpable purpura that don’t blanch

Red to purple in color

7
Q

Other causes of palpable purpura

A

Disseminated meningococcal or gonococcal

Rocky Mountain spotted fever

8
Q

Hallmark lab finding of churg Strauss

A

Eosinophilia

9
Q

C-ANCA positive is diagnostic for what

A

Wegners granulomatosis

10
Q

P-ANCA positive is seen in what vasculitis

A

Microscopic polyangitis

Churg-Strauss

11
Q

Definitive test to document inflammation and destruction of vessels

A

Biopsy

12
Q

Mainstay of tx for wegners granulomatosis, microscopic polyangitis, polyarteritis nodosa

A

Prednisone and cyclophosphamide

13
Q

Tx for temporal arteritis and churg Strauss

A

Prednisone

14
Q

Peak age of RA

A

40-50

15
Q

Gender more at risk for RA

A

Female

16
Q

What causes RA

A

Synovial T cells become activated and synovial lining becomes invasive causing erosion and destruction of joint cartilage

17
Q

High levels of what factors in RA synovial fluid

A

Tumor necrosis factor alpha

Interleukin-1

18
Q

Key feature with RA

A

Morning stiffness >1 hour

19
Q

RA deformity at the PIP

A

Boutonnière deformity

20
Q

RA deformity at the DIP

A

Swan neck deformity

21
Q

Most commonly affected joints with RA

A

Proximal inter phalangeal
mCP
Wrist

22
Q

What is the syndrome with splenomegaly, RA, leukopenia

A

felty syndrome

23
Q

Presents with GU or GI dz and asymmetric lower extremity arthritis

A

Reactive arthritis

24
Q

Presents with monoarticular knee arthritis with preceding rash and fever

A

Lyme disease

25
Q

Lab tests for RA

A

RF
Anti-CCP
Plain films of hands

26
Q

What is used as a bridge for RA when waiting for DMARDs to kick in

A

Corticosteroids

27
Q

Most common DMARD and adrs

A

Methotrexate- bone marrow toxicity, hepatic fibrosis, pneumonitis’ stomatitis

28
Q

Pyrmidine synthesis inhibitior used for RA. Adrs include diarrhea and rash

A

Leflunomide

29
Q

Extra-articular manifestations of RA

A

Rheumatoid nodules
Pleural effusions
Vasculitis
Felty syndrome

30
Q

Associated conditions with RA

A

Atlantoaxial subluxation

Baker cyst