Rheumatology

Question 0

Vasculitis that affects visceral arteries and can present with abdominal pain

Answer 0

Polyarteritis nodosa

Question 1

What is a vasculitis that attacks the coronary arteries in young children

Answer 1

Kawasaki disease

Question 2

Vasculitis that presents as recurrent asthma attacks

Answer 2

Chung-Strauss

Question 3

Vasculitis that presents as recurrent sinusitis, dyspnea’ and/or hemoptysis

Answer 3

Wegener granulomatosis

Question 4

Vasculitis that presents with new onset HA, scalp tenderness, and jaw claudication

Answer 4

Temporal arteritis

Question 5

Vasculitis that affects large vessels and may cause syncope

Answer 5

Takayasu Arteritis

Question 6

PE signs with vasculitis

Answer 6

Palpable purpura that don’t blanch

Red to purple in color

Question 7

Other causes of palpable purpura

Answer 7

Disseminated meningococcal or gonococcal

Rocky Mountain spotted fever

Question 8

Hallmark lab finding of churg Strauss

Answer 8

Eosinophilia

Question 9

C-ANCA positive is diagnostic for what

Answer 9

Wegners granulomatosis

Question 10

P-ANCA positive is seen in what vasculitis

Answer 10

Microscopic polyangitis

Churg-Strauss

Question 11

Definitive test to document inflammation and destruction of vessels

Answer 11

Biopsy

Question 12

Mainstay of tx for wegners granulomatosis, microscopic polyangitis, polyarteritis nodosa

Answer 12

Prednisone and cyclophosphamide

Question 13

Tx for temporal arteritis and churg Strauss

Answer 13

Prednisone

Question 14

Peak age of RA

Answer 14

40-50

Question 15

Gender more at risk for RA

Answer 15

Female

Question 16

What causes RA

Answer 16

Synovial T cells become activated and synovial lining becomes invasive causing erosion and destruction of joint cartilage

Question 17

High levels of what factors in RA synovial fluid

Answer 17

Tumor necrosis factor alpha

Interleukin-1

Question 18

Key feature with RA

Answer 18

Morning stiffness >1 hour

Question 19

RA deformity at the PIP

Answer 19

Boutonnière deformity

Question 20

RA deformity at the DIP

Answer 20

Swan neck deformity

Question 21

Most commonly affected joints with RA

Answer 21

Proximal inter phalangeal
mCP
Wrist

Question 22

What is the syndrome with splenomegaly, RA, leukopenia

Answer 22

felty syndrome

Question 23

Presents with GU or GI dz and asymmetric lower extremity arthritis

Answer 23

Reactive arthritis

Question 24

Presents with monoarticular knee arthritis with preceding rash and fever

Answer 24

Lyme disease

Question 25

Lab tests for RA

Answer 25

RF Anti-CCP Plain films of hands

Question 26

What is used as a bridge for RA when waiting for DMARDs to kick in

Answer 26

Corticosteroids

Question 27

Most common DMARD and adrs

Answer 27

Methotrexate- bone marrow toxicity, hepatic fibrosis, pneumonitis' stomatitis

Question 28

Pyrmidine synthesis inhibitior used for RA. Adrs include diarrhea and rash

Answer 28

Leflunomide

Question 29

Extra-articular manifestations of RA

Answer 29

Rheumatoid nodules Pleural effusions Vasculitis Felty syndrome

Question 30

Associated conditions with RA

Answer 30

Atlantoaxial subluxation | Baker cyst