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SG 3 BACTERIOLOGY > RICKETTSIA > Flashcards

RICKETTSIA Flashcards

(54 cards)

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1
Q

RICKETTSIA KEY FACTS

A

OBLIGATE INTRACELLULAR
CULTURED IN YOLK SAC OF EMBRYONATED EGGS OR IN SELECT TISSUE CULTURE CELL LINES
STAINED BY ROMANOWKSKY
VECTOR BORNE- SPREAD BY TICKS, FLEAS, LICE, MOSQUITO
ZOONOTIC
INTERMEDIATE BETWEEN VIRUSES AND BACTERIA
EMERGING AND RE-EMERGING DISEASES
OBLIGATE INTRACELLULAR

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2
Q

RICKETTSIA TARGETS WHAT

A

ENDOTHELIUM

CAUSES VASCULITIS

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3
Q

RESERVOIRS OF RICKETTSIA

A

SMALL MAMMALS AND RODENTS

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4
Q

TRANSMISSION OF RICKETTSIA

A

ARTHROPOD BITE OR INHALATION OF ARTHROPOD FECES

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5
Q

RICKETTSIA CAUSES WHAT

A

SPOTTED FEVER

THYPUS

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6
Q

R. RICKETTSIA CAUSES

A

ROCKY MOUNTAIN SPOTTED FEVER

TICK VECTOR- DERMACENTOR

HOSTS- HUMANS, DOGS

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7
Q

R FELIS CAUSES

A

FLEA-BORNE SPOTTED FEVER

CAT FLEAS (CTENOCEPHALOIDES)

HUMAN HOST

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8
Q

R. TYMPHI CAUSES

A

MURINE TYPHUS

RAT AND CAT FLEAS
XENOPSYLLA AND CTENOCEPHALOIDES

HOST-HUMANS

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9
Q

ROCKY MOUNTAIN SPOTTED FEVER

A

SLYVATIC CYCLE IN WILDLIFE IMPORTANT- SMALL MAMMALS AND RODENTS
RANGE OF INFECTION DEPENDS ON TICK DISTRIBUTION

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10
Q

ROCKY MOUNTIAIN SPOTTED FEVER, R RICKETTSIA VIRULENCE FACTORS

A

PHOSPHOLIPASE AND PROTEASE DAMAGE MEMBRANES OF ENDOTHELIUM

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11
Q

R RICKETTSIA REPLICATES WHERE

A

CYTOPLASM AND NUCLEUS OF HOST CELL

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12
Q

R. RICKETTSIA CAUSES ENDOTHELIAL DAMAGE THAT INITIATES

A

VASCULITIS, PLATELET ACTIVATION, DIC, NECROSIS

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13
Q

R. RICKETSSIA- ROCKY MOUNTAIN SPOTTED FEVER CLINICAL SIGNS

A

FEVER DEPRESSION ANOREXIA SUBCUTANEOUS EDEMA PETECHIA IN MUCOSA MYALGIA

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14
Q

CAT FLEA TYPHUS LIKE ILLNESS - SPOTTED FEVER

A

R FELIS
CATS ARE ASYMPTOMATIC
VETOR CTENOCEPHALOIDES FELIS
SYLVATIC CYCLE =OPOSSUMS

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15
Q

MURINE TYPHUS

A

CAUSED BY RICKETTSIA TYPHI VECTOR C. FELIS AND XENOPHYLLA
RESERVOIRS- RODENTS, CATS, OPOSSUMS
ENDEMIC TO S.CALIFORNIA AND TEXAS
TRANSMISSION SCRATCHING OF INFECTED FLEA FECES INTO A BITE WOUND
HUMANS

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16
Q

R. RICKETTSIA IN DOGS CAUSES

A

THROMBOCYTOPENIA

SEROLOGY***** (BUT CANT TELL BW/ THYPHUS GROUP)

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17
Q

TREATMENT OF RICKETTISIA

A

DOXYCYCLINE
TETRACYCLINE
ENROFLAXIN
CHLORAMPHENICOL

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18
Q

ANAPLASMATACEAE

A

ANAPLASMA
EHRLICHIA
NEORICKETTSIA

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19
Q

ANAPLASMATACEAE IS EXTRACELLULAR OR INTRACELLULAR

A

INTRACELLULAR IN LEUKOCYTES, ERYTHROCYTES, ENDOTHELIAL CELLS, PLATELETS

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20
Q

WHAT VECTORS FOR ANAPLASMATACEAE

A

NEORICKETTSIA- TREMATODE

ANAPLASMA AND EHRLICHIA - TICKS

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21
Q

RESERVOIRS FOR ANAPLASMATACEAE

A

WILDLIFE

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22
Q

ANAPLASMATACEAE KEY POINTS

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A

OBLIGATE INTRACELLULAR
LACK A GLYCOLYSIS CYCLE
LACK A CELL WELL SENSITIVE TO MECH STRESS
INHABIT CELL MEMBRANE DERIVED VACUOULES IN HEMATOPOETIC CELLS OF MAMMALS
FORM MORULA- CLUSTERS

23
Q

EHRLICHIA CANIS

Study These Flashcards
A

DOGS
CANINE MONOCYTOTROPHIC EHRLICHIOSIS
MONOCYTES

24
Q

EHRLICHIA CHAFFEENIS

Study These Flashcards
A

HUMAN MONOCYTOTROPHIC EHRLICHIOSIS

HUMANS, DOGS, GOATS

25
EHRLICHIA EWINGII
INFECTS DOGS AND HUMANS | INFECTS GRANULOCYTES MAINLY NEUTROPHILS
26
ANOPLASMA PHAGOCYTOPHILUM
INFECTS GRANULOCYTES MAINLY NEUTROPHILS | DOGS, CATS, HUMANS, HORSES, RUMINANTS AND LLAMAS
27
ANAPLASMA PLATYS
INFECTS PLATELETS DOGS NOT ZOONOTIC
28
ANAPLASMA PHAGOCYTOPHILUM RESERVOIRS
SMALL MAMMALS AND DEER BIRDS ARE AMPLIFIERS
29
ANAPLASMA PHAGOCYTOPHILUM VECTOR
IXODES TICKS
30
GRANULOCYTIC ANAPLASMOSIS PATHOGENESIS
``` APOPTOSIS INHIBITION EVASION OF IMMUNE SYSTEM MULTIPLICATION FORMULATION OF MORULA RELEASE IMPAIRMENT OF PHAGOCYTOSIS AND NEUTROPHILS ```
31
ANAPLASMA PHAGOCYTOPHILUM CAUSES ____ IN THE BLOOD
THROMBOCYTOPENIA
32
CLINICAL SIGNS OF ANAPLASMA PHAGOCYTOPHILUM
FEVER, LETHARGY, MUSCULOSKELETAL PAIN
33
DOES ANAPLASMA PHAGOCYTOPHILUM REQUIRE TREATMENT
NO IT IS SELF LIMITING
34
WHAT DOES ANAPLASMA PHAGOCYTOPHILUM CAUSE IN HORSES ?
MILD EDEMA IN LIMBS, ATAXIA, DIC
35
CANINE CYCIC THROMBOCYTOPENIA
ANAPLASMA PLATYS
36
ACUTE INFECTIONS OF ANAPLASMA PLATYS
FEVER, PETECHIA, ECCYMOSIS | THROMBOCYTOPENIA CYCLIC !!!!!! DUE TO MULTIPLICATION CYCLES OF BACTERIA
37
BOVINE ANAPLASMOSIS
ANAPLASMA MARGINALE | BACTERIA IN ERYTHROCYTES (MARGINALLY)
38
YOUNGER CATTLE IN ENDEMIC AREAS GET SEVERE ANAPLASMOSIS T/F
FALSE THEY GET AN IMMUNE RESPONSE | CARRIER STATE
39
NAIVE ADULTS GET SEVERE DISEASE DESCRIBE
ERYTHROCYTES RUPTURE, ICTERUS, ANEMIA STRESS IS TRIGGER OF CLINICAL SIGNS SEPARATE INF ANIMALS OXYTETRACYCLINE
40
CANINE MONOCYTIC EHRLICHIOSIS
EHRLICHIA CANIS
41
EHRLICHIA CANIS VECTOR
RHIPHICEPHALUS SANGUINEUS
42
ECHLICHIA CANIS RESERVOIRS
COYOTE, FOX, JACKAL, DOMESTIC DOGS
43
EHRLICHIA CANIS PATHOGENESIS
ADHERENCE TO INVADE CELLS REPLICATION IN VACUOLES TO EVADE IMMUNE SYSTEM ABSENCE OF LPS ALLOW SURVIVAL IN HOST IMMUNE AND INFLAMMATORY RESPONSE THROMBOCYTOPENIA- PLATELET CONSUMPTION, DECREASED PLATELET HALF LIFE, IMMUNE MEDIATED DESTRUCTION PANCYTOPENIA- BONE MARROW SUPPRESSION HYPERGLOBULINEMIA
44
CANINE MONOCYTIC EHRLICHIOSIS PHASES
ACUTE FEVER, THROMBOCYTOPENIA LASTS 4 WEEKS, MORULAS IN THE BLOOD SMEAR SUBCLINICAL INFECTION FEVER, THROMBOCYTOPENIA, ANEMIA FOR MONTHS TO YEARS CHRONIC FEVER WIDESPREAD PETECHIA, EDEMA, SUPPRESSED BONE MARROW- DEATH
45
ACUTE OR CHRONIC PHASE SHARE THESE CLINICAL SIGNS
LYMPHADENOPATHY, SPLENOMEGALY, NASAL BLEEDING
46
DIAGNOSIS OF EHRLICHIA AND ANAPLASMA
TICK EXPOSURE, CLINICAL SIGNS, BLOOD SMEAR, TISSUE ASPIRATES SPLEEN BONE MARROW LN, SEROLOGY GOOD FOR CHRONIC, PCR PREFERRED METHOD ***
47
NEORICKETTSIA VECTOR AND RESERVOIR
VECTOR- TREMATODE RESERVOIR- SNAIL RESERVOIR- WATER INSECTS - INGEST WHILE DRINKING WATER
48
NEORICKETTSIA RISTCII
EQUINE MONOCYTOTROPHIC EHRLICHIOSIS | POTOMAC HORSE FEVER
49
NEORICKETTSIA HELMINTHOECA
SALMON POISONING DISEASE IN DOGS
50
POTOMAC HORSE FEVER- NEORICKETTSIA RISTICII CLINCIAL SIGNS
FEVER, DIARRHEA, COLIC, ANOREXIA, LEUKOPENIA, LAMINITIS, ABORTION, HEMORRHAGIC ENTEROCOLITIS
51
NEORICKETTSIA RISTICII INFECTS WHAT CELLS
ENTEROCYTES AND MONOCYTES
52
DIAGNOSIS OF NEORICKETTSIA RISTICII
PCR OF BLOOD OR FECES
53
TREATMENT OF NEORICKETTSIA RISTICII
EARLY DIAGNOSIS IS KEY TREAT WITH OXYTETRACYCLINE MINIMIZE INSECT INGESTION TURN OFF BARN LIGHTS AT NIGHT
54
SALMON POISONING DISEASE
NEORICKETTSIA HELMINTHOECA FEVER, DEPRESSION, DEHYDRATION, ANOREXIA, VOMITING, HEMORRHAGIC DIARRHEA, DEATH WITHOUT TREATMENT TETRACYCLINE AND PRAZIQUANTEL

SG 3 BACTERIOLOGY (17 decks)

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