Flashcards in RNA (+) Viruses II Deck (32)
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1
Adult rubella is characterized by
Lymphadenopathy, seizures, and arthritis
2
There is no treatment for
Rubella
3
However, there is a Rubella vaccine, which is the live attenuated
MMR vaccine
4
HIV patients should only receive the MMR vaccine if their CD4 counts are above
200
5
Rubella produces one long polyprotein protein precursor that is cleaved by proteases. The BIG BUZZWORD for Rubella is
Immigrant
6
What is the viral classification of corona virus?
Encapsulated SS RNA positive virus
7
What is a major component of the corona viruses?
SARS
8
A helical virus that also causes the common cold
Corona virus
9
SARS and the middle east respiratory syndrome (forms of corona virus) cause
Acute bronchitis
10
All forms of corona virus replicate in the
Cytoplasm
11
Pos Sense RNA Single strand start but then DNA due to reverse transcription
Retroviruses
12
A major form of retrovirus
HIV
13
What is the viral classification of retrovirus?
Encapsulated
14
Diploid nature RNA virus
Retrovirus
15
The capsule for the RNA in a retrovirus is
Gag = p24
16
A transmembrane protein that codes for gp41 and 120
Env protein
17
What are the three important genes for HIV?
Gag, Env, and RT
18
A TORCHeS infection
HIV
19
HIV initially effects
Macrophages
20
Characterized by a prodromal like flu with cervical lymphadenopathy, tonsils may be enlarged. Fever
HIV
21
HIV is latent for 10 years, during which time it is replicating in
Lymph nodes
22
HIV progresses to AIDS when CD4 is below
200
23
HIV enters the macrophages and T Cells via
CCr5 and CXCr4
24
HIV enters the macrophages and T Cells via CCr5 and CXCr4 coreceptors, then will enter, uncoat, undergo
Reverse transcription
25
Elisa is used for screening of HIV and then it is confirmed via
Western blot
26
We measure the viral load of HIV and CD4 count via
PCR
27
All neonates will be positive, but may not actually have the
Disease
28
The backbone of any HART (HIV) therapy is
NRTI's
29
The best HIV treatment for pregnant patients
Zidovudine
30
Does not incorporate in RNA chain
-Inhibits reverse transcriptase
NNRTI's
31
Prevents cleavage of proteins for viral replication
Protease inhibitor
32
