RNA (+) Viruses II Flashcards Preview

Sketchy: Viruses > RNA (+) Viruses II > Flashcards

Flashcards in RNA (+) Viruses II Deck (32)
Loading flashcards...
1

Adult rubella is characterized by

Lymphadenopathy, seizures, and arthritis

2

There is no treatment for

Rubella

3

However, there is a Rubella vaccine, which is the live attenuated

MMR vaccine

4

HIV patients should only receive the MMR vaccine if their CD4 counts are above

200

5

Rubella produces one long polyprotein protein precursor that is cleaved by proteases. The BIG BUZZWORD for Rubella is

Immigrant

6

What is the viral classification of corona virus?

Encapsulated SS RNA positive virus

7

What is a major component of the corona viruses?

SARS

8

A helical virus that also causes the common cold

Corona virus

9

SARS and the middle east respiratory syndrome (forms of corona virus) cause

Acute bronchitis

10

All forms of corona virus replicate in the

Cytoplasm

11

Pos Sense RNA Single strand start but then DNA due to reverse transcription

Retroviruses

12

A major form of retrovirus

HIV

13

What is the viral classification of retrovirus?

Encapsulated

14

Diploid nature RNA virus

Retrovirus

15

The capsule for the RNA in a retrovirus is

Gag = p24

16

A transmembrane protein that codes for gp41 and 120

Env protein

17

What are the three important genes for HIV?

Gag, Env, and RT

18

A TORCHeS infection

HIV

19

HIV initially effects

Macrophages

20

Characterized by a prodromal like flu with cervical lymphadenopathy, tonsils may be enlarged. Fever

HIV

21

HIV is latent for 10 years, during which time it is replicating in

Lymph nodes

22

HIV progresses to AIDS when CD4 is below

200

23

HIV enters the macrophages and T Cells via

CCr5 and CXCr4

24

HIV enters the macrophages and T Cells via CCr5 and CXCr4 coreceptors, then will enter, uncoat, undergo

Reverse transcription

25

Elisa is used for screening of HIV and then it is confirmed via

Western blot

26

We measure the viral load of HIV and CD4 count via

PCR

27

All neonates will be positive, but may not actually have the

Disease

28

The backbone of any HART (HIV) therapy is

NRTI's

29

The best HIV treatment for pregnant patients

Zidovudine

30

Does not incorporate in RNA chain

-Inhibits reverse transcriptase

NNRTI's

31

Prevents cleavage of proteins for viral replication

Protease inhibitor

32

A CCR5 inhibitor used to treat HIV

Miravoroc