RP Flashcards

1
Q

what endocanniboids act on

endorphin
enkephalin
dynorphin

A

endorphin = mu
enkephalin -delta
dynorphin - kappa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

mum leaves, no emotion when returns from kiddo

A

avoidant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

provides guidance but not done alone

A

vygotsky
zone of proximal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

clinician rated

A

HAMD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

infradium

A

longer than 24 hour
e.g. menstrutation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

prazocsin

A

PTSD
and BPH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

low bioavability

A

poor absorption -lurasidone
wide distribution -chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

brain organoid

A

2nd trimester

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what to check in atoxemine

A

BP
as increases hr AND BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what to check before aglomelatine use

A

liver function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

rhodosporin responds to

A

blue light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is esketamine

A

NMDA antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

duloxetine half life

A

12 hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

elevated maze in rats/mice

A

anxiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

preimpulsion test

A

weak pre-impulse
startle
reduction in startle in schizophrenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

temp regulation in hypothalamus

A

anterior -hypothermic
posterior -hyperthermic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

propiomelanocortin is associated with

A

ACTH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

top down vs bottom up

A

top down -guided by knowledge
bottom up-sensory first then build up perception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

terbetazine

A

VMAT 2 !!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

WHAT CAN nalaxone do

A

bypass placebo affect
inhibit it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

catie study

A

tolerability - zupirasidone
effiacy -clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

psilocybin

A

5HT2A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

difference between chimera and mosaic

A

chimera - mopre 1 zygote
mosaic - 1 zygote

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are examples of gottmann institution

A

moritifcation- loss of self
institutionalisation
betrayal -reported by family friends

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
memory loss and benzo receptor
alpha 1
26
onerioid
dream like state
27
diff between schizoid and schizotypal
schizotypal -magical thinking schizo - indifferent to criticism
28
detouring
family dyanmic against 1 fam member
29
ubiquitin
chr 17
30
receptor for pitloisant
HT3
31
punding
parkinson sorting objects, items eccessively
32
which are unstable and stable temperaments
unstable -choleric , melancohilic stable - sanguine and phlegamtic
33
what is token economy
behaviour suystem behaviour reinforced with token (secondary refinrocement) and later echanged for rewards.
34
difference between retroactive and proactive
new info replaces old for retroactive i.e. old number replaced by new mobile number proactive - old inteferes with new
35
contangion theory
hypootic influence influenced by those arounf echo -social media hysterical covid 19
36
crowd theory
contagion convergence - similarites from begnning emergent norm - new trends emerge and spread i.e. ice bucket
37
four types of suicide
alutristic - social norms/rituals egoistic - self indiivudalisim, excessive low integrayion fatalistic suicide- control on the individual by society anaomic -lack of guidance or regulations from system e.g. overwehlmed when winning lottery
38
VARIABLE RAITO continous
most resistent e.g. gambling easy to extinct intermittent refinforcement -longest tto establish
39
what is mind in the eyes
by cohen lots of sets of eyes adutls with autism to depice emotional state
40
what is dihsinhibited social engagement disorder
inadequate child care approaching adults indicrimminately, willingness to go with strangers , overly familar behaviours towards stranger
41
kleine defence mechanism
SIP DOG Splitting introjection projective identification denial gransodity omnipotence
42
what is paraminia
disorganised facial expressions
43
what is parathymia
inappropriateness of affect
44
delusion disorder
ICD 1 MONTH DCSM - 3 MONTH
45
timing for gaming disorder
12 months
46
difference between vomiting and laxarive use
vomtiing - metabolic alkaosis laxative use - sodium low, acidosis metabolic
47
most common type of ocd
contimatinion
48
ocd with genetic risk highest in 1st degree relatives
symmetry (also see with slowing) ordering rituals
49
kade kuhn kline
cade -lithium kuhn- inpramine kline -MOAI iprazmid kane -clozapine
50
lirhium tremor is
10hz
51
fine vs coarse temor
fine - long term coarse -toxicity
52
difference between social and unsocial conduct disorder
presence of friends or not
53
child or adolesence
before or after 10 year old
54
impotence vs priapism
alpha. 1pripaism impoetence alpha 2
55
doesnt pass BBB
doapmine sertaonin sulpride /amisulpride
56
passes BBB
levadopa
57
hallucinogens
impact seratonin LSD pisbo DMT Mesocaline agonist of 5HT2A
58
dissociative drugs
KETAMINE PCP DXM NO impacts glutamate NDMA antagonist
59
canniboid receptors
THC CB1 AND CB2
60
antidepressant by IM
fluxopenthixol mood elevating
61
buccal antidepressant
selegline and amtriplyline
62
most adrengeic antidepressant
desimpramine
63
most antihistamingeric
doxepin
64
rectal antidepressant
trazone ipramine amitryplline
65
antidepressant prostatism in elderly
amitrprylline
66
venlafaxine
raise bP
67
shortest half life antidepressant
fluvoxamine
68
antidepressant in diabetes
setraline duloxetine
69
autoinhbition antidepressant
also anti cholingeric paroxetine
70
antidepressant half lives
fluvoxamine 14 hour paroxetine 21 hr sertraline 26-36 hr citalopram 33 hour fluxoetine 7-15 days. 5.6 days
71
which antidepressant impacted by smoking
duloxetine also reduced levels with gastric bypass
72
antidepressant best antiemetic
mirtazpine
73
difference between amisulpride and sulpride
sulpride d2 amisulrpide d2/d3
74
myocarditis clozapine montioring
oesphilia most reliable trop most sensitive
75
seizure and cloza 300 300-600 >600 dose
1-2% 3-4 5%
76
benzo longest half life
diazepam
77
treatment for premature ejaculation
dapoxetine
78
which anti depressants cause delayed ejuculation
citalopram fluxotine
79
retinal pigmentation
thirodidazine
80
which meds with a meal >500 calories
lurasidone ziprasidone
81
decreased with food absroption
diazepam
82
amantadine used in
influenze parkinsonism
83
antiepeilpetic sith aggressive behaviour
levetiretam vigabatrin toperimate
84
depo switching to oral
depo 3-6 month then go to oral once steady plasma level
85
akathasia high with
HRAZ haloperidol risperidone aripiprazole ziprasidone
86
steady state lithium clozapine sodium val
5 days 2-3 days 2-3 days
87
cocaine methylphedinate mdma
cocaine and methylphedinate - DAT mdma blocks sert
88
drug metabolism cannabis chronci cannabis occasional herion methadone cocaine ampjetamine angel dust benzo
cannabis chronic 30 days , ocassional 1-3 days herion 1-3 days methadone -up to 7 days cocaine 2-4 days amphetamiens 48 hours angel dust -8 days benzo 24 hour
89
difficulty in gait initiation w/o tremors
normal pressure hydrocephalus
90
what artery is affected in hemianiopia homogenous
MCA
91
artery in quadrantopoia
MCA
92
alexia without agraphia proposgonosia contralateral hemianopia ipelsilateral cranial nerve deficit
PCA left
93
akinetic mutism
bilateral ACA
94
most sediating antidepressant
pareoxtine anticholngeric also short half life
95
location for procedural and long term memory
LT memory - hippocampus procedural - cerebellum
96
default mode network
MAPPP Medial prefrontal cortex precuneus medial, lateral and inferior Pareital lobe posterior cingulate cortex angular gyrus
97
salience network
ACTS anterior insula dorsal anterior cingulate cortex thalamus straitum
98
central executiv network
DIP dorsolateral prefrontal cortex intraparietal sulcus posterior pareital cortex
99
verbal and visual working memory parts of brain
verbal LEFT DLPC visual right DLPC
100
which encephalitis is associated with lung cancer
AMPAR
101
how do you differential broca from transcortical motor
repetition is intact whereas lost in broca
102
how do u differentiate transcortical sensory from wernikes
repetition intact !!!
103
conduction aphasia
broca and wernike intact stuff but loss of repetition
104
deep brain stimulation in : depression ocd parkinson tourettes
depression: stimulate cingulate gyrus OCD: anterior limb of internal capsules parikinson - subthalamic nucleus and globus pallidus tourettes: ventromedial
105
trans cranial magnetic Stimulation
frontal left in depression
106
difference between T1 and T2 MRI
T1 enhance fatty tissue T2 -enhance signal of water
107
what does PET scan use
11 c labelling brain metabolism by tagging organic compounds
108
what does MRS used
hydrogen and phosphate 31
109
what does spect use
technietium 99 xenon 123 idoine 123 gamma rays
110
dti looks at
myelination
111
DAT scan looks at
dopamine transporter scan
112
which class of antideprssant can cause noctural myoclonus
ssri
113
which antidepressant associated with seizure
bupropion
114
which condition hypoperfusion of corpus collosum
MS
115
gertstmann syndrome affects
supramarginal area
116
how to manage restless syndrome
levodpoa ropinole dopamine agonist
117
pragmattism
jumbled sentences
118
xanomeline works by
M1/M4
119
hypersalvation in clozapine mechanism
m4 agonism alpha 2 antagonism
120
which meds do not interact with lithium
haloperidol cloza
121
what can wais be divided into
verbal -words performance (pictures, shapes)
122
what are dominant pareital lesions
RL diorientation dyscalculia agraphia finger agnosia
123
monoamine a AND B coded by which chromosome
X
124
what happens to glutamate in alzehimers
increases
125
sigma receptors in
depression
126
eeg changes in sleep
sleep stage 1 - theta waves sleep stage 2 - k. and spinges sleep stage 3 - delta <50% sleep stage 4 - delta >50 rem sleep - saw tooth
127
learning in gambling observaton alone
variable ratio modelling
128
whats fahr syndrome
calcification of basal ganglia
129
what is biswanger
slow decline in memory subcortical leukorossis small vessel damage
130
130
what is cyproterone
blocks testosterone
131
rivastigamine is not affected by
renal impairment
132
enactive theory of perceputal and mental imagery
action cycle 6 steps SOA AGO schemata objects action affect goals others behaviour
133
capriprazine
d2/d3 agonist parital 5HT1A 5HT2A AND B antagonist
134
ect reduces what
acetylcholine
135
ikr potassium is coded by
herg
136
lG1nmdar encephalitis
flu like
137
LG11
hyponatraemia
138
d2 occupancy and sensitivity increased
occupancy -parkinson sensitivity -tard dyskinesia
139
what is seen on scan with lithium
thickening of grey matter
140
deliquenscence what age
8 to 10 years
141
what is seen in blood and urine with wilsons
reduced ceurloplasmin reduced serum copper incresed urinary copper
142
mirror neurons in humans
inferior frontal gyrus broca area mirroring people
143
lurasidone mechanism of action
5ht7 5ht2a d2