Rush Rh Group

Question 1

2nd important group

Answer 1

Rh

Question 2

antigens are very what in rh group

Answer 2

immunogenic

Question 3

how many antigens in rh

Answer 3

61

Question 4

what kind of antibodies in rh and what does it cause

Answer 4

immune in nature
hdfn and htr

Question 5

rh typing tests what

Answer 5

d antigen presence

Question 6

year where ppl still kept dying even if ABO crossmatching is done

Answer 6

1939

Question 7

discovered that HTR due to husband blood after mother gave birth to inborn infant

Answer 7

levine and stetson

mother got exposed to rh antigen from baby, so she died even if they were abo compatible with the papa

Question 8

reported antibodies via guinea pigs and rabbits post transfusion with rheesus monkey rbc

Answer 8

landsteiner and weiner

Question 9

they further examined the HTR incident and the rheesus monkey incident and said “yeah they’re the same”

Answer 9

Levine et al.

Question 10

humans produced antibodies are called
and what are animal antibodies called

Answer 10

humans Rh
animals Anti-LW

Question 11

four nomencaltures for rh?

Answer 11

fisher race
wiener
rosenfield
isbt

Question 12

basis for rh nomenclature

Answer 12

postulated genetics
yes or no of antigens
efforts of ISBT

Question 13

this is one set of the rh gene

Answer 13

D C/c E/e

Question 14

how are rh genes expressed

Answer 14

codominantly

Question 15

postulated that rh gene produces an agglutinigen that contains a series of blood factors

Answer 15

weiner rh-hr system

Question 16

two types of weiner nomenclature

Answer 16

genotype (haplotype) and antigen weiner system

Question 17

name all fisher race permutations for rh antigens

Answer 17

Dce
DCe
DcE
DCE
ce
Ce
cE
CE

Question 18

give the corresponding weiner antigen system to the fisher race system of:

D
C
E
c
e

Answer 18

D is Rho
No D is left blank
C is rh’
E is rh’’
c is hr’
e is hr’’

Question 19

give the corresponding weiner haplotype system to the fisher race system of:

D
C
E
c
e

Answer 19

D is anything with big R
no D is just r

subscripts for R
o means all small c and e
1 means only C is big
2 means only E is big
Z means all big CE

superscripts for r
none means all small ce
‘ means big C only
‘’ means big E only
y means all big CE

Question 20

two characteristics of rh antigens

Answer 20

naturally occuring
immune

Question 21

why cant we have RhCc or RhEe?

Answer 21

C/c or E/e are antithetical

Question 22

difference between genotype and phenotype

Answer 22

genotype is the actual gene expression (AO)
phenotype is the physical manifestation (A)

Question 23

they assigned a system that where there is a number to each rh antigen

Answer 23

rosenfield alphanumeric terminology

Question 24

what designates an absence of an antigen in rosenfield system

Answer 24

(-) sign

Question 25

what corresponds to the rosenfield system for the fisher race: D C E c e

Answer 25

D is 1 C is 2 E is 3 e is 4 c is 5

Question 26

this adopted six digit number for each blood group specificity

Answer 26

ISBT Committee

Question 27

in ISBT first three digits is for? and last three digits?

Answer 27

first three is the system last three is the antigen

Question 28

translate to ISBT commitee the following fisher race nomenclature: Rh D C E c e

Answer 28

Rh is the system so it's first 004 the antigen last three are D is 001 C is 002 E is 003 c is 004 e is 005

Question 29

this nomenclature system says rh antigens are produced by 3 closely linkled alleles

Answer 29

Fisher Race DCE Terminology