Schizophrenia

Question 1

Schizophrenia definition

Answer 1

Chronic mental disorder with periods of psychosis, disturbed behavior, and thought and decline in functioning

Lasting > 6 months

Associated with increased dopamine and decreased dendritic branching.

Question 2

Schizophrenia diagnosis

Answer 2

Diagnosis requires 2 or more of the following:
(positive symptoms)
Delusion
Hallucination-often auditory
Disorganized speech (loose association)
Disorganized or catatonic behavior

(negative symptoms)
Flat affect
Social withdrawal
Lack of motivation
Lack of speech or thought

Question 3

Brief psychotic disorder

Answer 3

Less than 1 month, usually stress related

Question 4

Schizophreniform disorder

Answer 4

1-6 months

Question 5

Schizoaffective disorder

Answer 5

AT LEAST 2 wks of stable mood with psychotic symptoms
PLUS
a major depressive, manic or mixed (both)

Two subtypes:

1) bipolar
2) depressive

Question 6

Schizophrenia subtypes (5)

Answer 6

1) paranoid (delusion)
2) disorganized (with regard to speech, behavior, affect)
3) catatonic (automatism)
4) undifferentiated (elements of all types)
5) residual

Question 7

Schizophrenia etiologies

Answer 7

Genetics and environment

Frequent weed use

Lifetime prevalence 1.5% (male=female, black=white)
Presents earlier in men (late teens to early 20s vs. late 20s to early 30s in women)

At increased risk for suicide