SNRI Flashcards

1
Q

SNRI

A

Venlafaxine

Duloxetine

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2
Q

MOA

A

Inhibit serotonin and NE reuptake

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3
Q

Clinical use

A

Depression

Venlafaxine: also GAD and panic
Duloxetine: also diabeteic peripheral neuropathy

Duloxetine has greater effect on NE

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4
Q

Toxicity

A

Increased BP most

Also stimulant effect, sedation, nausea

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