Sd de lyse tumorale Flashcards

1
Q

Biologie du sd de lyse tumorale

A

​hyperkaliémie

hypocalcémie

hyperphosphorémie

hyperuricémie

insuffisance rénale tubulaire

complications : CIVD, anémie, infections

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2
Q

PEC du syndrome de lyse tumorale

A

urgence

hydratation alcaline

hypo-uricémiant

EER

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3
Q

Quelles sont les 2 complications du sd de lyse tumorale ?

A
  1. insuffisance rénale : NTA par précipitation cristaux d’acide urique/phosphate de calcium
  2. hyperkaliémie –> TdR
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4
Q

Facteurs de risque de lyse tumorale

A

Hémopathies malignes agressives :

  • lymphome agressif, surtout si forte masse tumorale
  • LAM
  • LAL
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5
Q

Prévention du sd de lyse tumorale

A

hyperhydratation alcaline

+/- diurèse forcée (furosémide)

hypo-uricémiant oral (Allopurinol)

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