SECOND PRIORITY (3) Flashcards

(33 cards)

1
Q

surra is transmitted by hematophagous flies called:

A

stomoxys and tabanus

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2
Q

CA of surra

A

t. evansi, congolense, brucei, vivax

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3
Q

trypanosomiasis pathogenesis

__ into skin via insect bite

Localized swellings

Infect __

Rapid division in the bloodstream

____– attach to endothelial cells
_____ - invade tissues and
cause damage

A

Tryopanosomes into skin via insect bite

Localized swellings

Infect LN

Rapid division in the bloodstream

*T. congolense – attach to endothelial cells
*T. brucei and T. vivax - invade tissues and
cause damage

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4
Q

T. evansi infections of cattle and buffalo usually
lead to pronounced

A

immunosuppression

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5
Q

ausative agent of leptospirosis

A

l. interrogans

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6
Q

earned its name from a characteristic hooked appearance that resembles a question mark

A

leptospirosis

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7
Q

t/f all serovars of Leptospira are pathogenic, and many are associated with a reservoir species in which little disease is apparent.

A

f

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8
Q

many serovars are highly prevalent within maintenance host populations and persist in the ___ and ___

A

kidneys or genital tract.

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9
Q

high antibody responses and low tissue burdens are typical in these animals. with lepto

A

low abs

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10
Q

leptospira is resistant to dessication T/F

A

freezing, dehydration, and UV radiation inactivate leptospires

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11
Q

majority of leptospira serovars have specific maintenance hosts

A

t

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12
Q

Leptospira serovars known to cause disease in mammals have been isolated from __

A

amphibians

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13
Q

3rd most impt dx in indonesia

A

surra

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14
Q

dz that can be inoculated in mice for lab dx

A

surra

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15
Q

pH preference of leptospira

A

neutral to slight alkalaine

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16
Q

all are serovars of canids except

a. bratislava
b. canicola
c. icterohemorrhagiae
d. pomona
e. hardjo
f. grippotyphosa

17
Q

lepto can be transmitted venerally or tranplacentally

A

t. but not all serovars

18
Q

encourages persistence of lepto in the environment.

19
Q

Maintenance hosts typically do not develop significant clinical disease

20
Q

develops rapidly and is a significant contributor to mortality in lepto infected animals

A

Acute renal injury

21
Q

hosts that develop reproductive disease acutely (lepto)

A

incidental hosts

22
Q

incidental hosts for lepto remain subclinical for weeks to months t.f

A

f. maintenance

23
Q

Best available method to determine infecting serovar of lepto

A

bacterial culture

24
Q

Does not provide serovar-specific results

25
standard serological test for diagnosing leptospirosis,
MAT
26
In experienced hands, the _ of leptospires is one of the most specific methods of demonstrating their presence,
isolation
27
agar used for culure of lepto
Bismuth sulphite agar
28
Addition of 0.4–5% ___ to semisolid culture medium enhances the chances of isolating fastidious leptospiral serovars
rabbit serum
29
less fastidious serovars of lepto
Pomona and Grippotyphosa
30
are increasingly used for the detection of leptospires in tissues and body fluids of animals because of their perceived sensitivity and capacity to give an early diagnosis.
PCR
31
Subsequent differentiation to the serovar level was traditionally by __, although for most isolates this is now being done using less time-consuming methods such as monoclonal antibodies (MAbs).
cross-agglutination absorption
32
is the laboratory procedure most frequently used to confirm the clinical diagnosis, to determine herd prevalence, and to conduct epidemiological studies
serology testing
33
uses live antigens is the most widely used serological test
MAT