Session 1 - Part II Flashcards

1
Q

Which part of the gonad will XX germ cells colonise?

A

The cortex

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2
Q

Which part of the gonad will XY germ cells colonise?

A

The medulla

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3
Q

What do female germ cells become when they colonise the gonadal cortex?

A

Oogonia (Diploid cells)

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4
Q

What do Oogonia do?

A

Proliferate rapidly by mitosis

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5
Q

When is the maximum number of Oogonia reached?

A

Mid gestation. However, most will die

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6
Q

When do Oogonia enter the first first phase of the 1st meiosis division?

A

Before birth. They are then suspended at this stage

Now called Primary Oocytes

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7
Q

What surrounds the Primary oocyte?

A

A single layer of granulosa cells of gonadal origin. Called primoridal follicle

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8
Q

When do the primordial follicles begin to develop further?

A

At puberty.

Most developing die, but one or two complete development and are released - ovulation

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9
Q

How long is the fertility period?

A

36 hours

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10
Q

What stage of the cycle precedes ovulation?

A

Preparation period

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11
Q

What happens in the Preparation period?

A

The ovum develops (Follicles developing)
The reproductive tract prepares for sperm transport and implantation (Uterus lining thickens)
The rest of the body undergoes changes to maximise chances of conception

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12
Q

What are the stages of the Menstrual cycle?

A

Preparatory phase (Follicular/proliferative phase)
Ovulation
Waiting phase (Leuteal/secretory phase)
It is timed from the onset of bleeding

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13
Q

What days in the menstrual cycle is the preparatory phase ?

A

0-12

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14
Q

What days in the menstrual cycle is the ovulation?

A

12-14

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15
Q

What days in the menstrual cycle is the waiting phase?

A

14-28

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16
Q

Why is there a waiting phase in the Menstrual cycle?

A

Because when the ovum is first fertilised it is too small to indicate its presence.

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17
Q

What happens in the waiting phase of the Menstrual cycle?

A

Further production of gametes is suspended until pregnancy can be confirmed by secretion of placental hormone

18
Q

What is the first stage in follicular development?

A

The primordial follicles develop to pre antral follicles (Aka secondary oocytes)
This is independent of hormones

19
Q

What are the cellular changes in the first stage in follicular development?

A

A zona pellucida develops
The single layer of granulosa develops into multiple
Theca interna & externa develop (Gonadal origin)

20
Q

What is the role of the Theca interna?

A

It is vascular and secretes hormones (eg oestrogen proportionally to size of the follicle. This is important for control)

21
Q

What is the role of the Theca interna?

A

It is thick and supports the follicle

22
Q

What triggers the pre ovulatory follicle to rupture and release the ovum?

A

Leuteinizing hormone

23
Q

When does meiosis restart in the ovum?

A

Just before ovulation

24
Q

How are polar bodies developed?

A

The first division of meiosis is completed, but the division is unequal which results in all the cytoplasm going to the oocyte and the extra DNA is disposed in a polar body.

25
Q

When is the second division of meiosis?

A

After fertilisation

26
Q

What is a corpus luteum?

A

A solid body of cells

27
Q

What happens to the follicle after ovulation?

A

It forms a corpus luteum
Grows under the influence of leuteinizing hormone
Secretes oestrogen & progesterone
Will die after 14 days if no ovum detected*

28
Q

Why does the follicle secrete oestrogen & progesterone after ovulation?

A

It makes the system wait

29
Q

Where do the XY germ cells colonise?

A

The sex cords which are in the testis

30
Q

Do the germ cells proliferate before birth in male embryos?

A

Yes via mitosis. Called spermatogonia

31
Q

Do spermatogonia stay in the testis for life?

A

Yes. It allows the male to have raw material to create sperm for his whole life

32
Q

What happens to the sex cords at puberty?

A

They hollow out forming seminiferous tubules (Blind ended tubules that end in the rete testis)

33
Q

What happens to spermatogonia at puberty?

A

They cluster around the periphery of the newly formed seminiferous tubules

34
Q

How are primary spermatocytes formed?

A

The spermatogonia divide by mitosis (A fixed number of times) to form a clone of cells all linked by cytoplasm (Remain diploid)

35
Q

How do primary spermatocytes form spermatids?

A

Meiosis begins and each spermatocyte forms 4 haploid spermatids. It moves towards the lumen as it does this.
Meiosis will be finished by the time it reaches the lumen

36
Q

When does the remodelling of spermatids to spermatozoa occur?

A

As they pass down the spermatic tubule through the rete testis, ductus efferentes and epididymus.

37
Q

How does a spermatozoa reach the urethra from the epididymus?

A

Via the vas deferens

38
Q

What constitutes semen?

A

Secretions of the seminal vesicle = 60%
Secretions of the prostate = 20%
Sperm (Via the vas deferens)
Secretions of the bulbo-urethral gland

39
Q

What controls the emission (Mixing) of semen?

A

The sympathetic branch of the ANS as it causes contraction of the smooth muscle in the walls of the tubules

40
Q

What controls the ejaculation of semen?

A

The parasympathetic branch of the ANS