Session 10 Flashcards
(3 cards)
1
Q
List some common potentially nephrotoxic drugs
A
ACE inhibitors, aminoglycosides (gentomycin), penicillins, cyclosporin A, metformin, NSAIDs
2
Q
List some cautions when prescribing in renal failure
A
Avoid nephrotoxins, reduce doses in line with GFR if metabolism/eliminated via the kidneys, monitor renal function and drug levels
3
Q
What are the main groups of calcium channel blockers and give their properties (and examples)?
A
Dihydropyridines - nifedipine/amlodipine. Short acting, baroreflex mediated tachycardia. Oral absorption good, highly protein bound.
Benzothiazepines - diltiazem
Phenylalkylamines - verapamil. Depresses SA node and slows AV conduction
All vasodilate arteries
