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Pharm 1 > Sketchy Adrenergic > Flashcards

Sketchy Adrenergic Flashcards

(68 cards)

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1
Q

Mime and Bear

A

Sympathomimetic

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2
Q

QISS

A

a1-Gq ; a2-Gi ; B1-Gs ; B2-Gs

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3
Q

Alpha scout

A

Alpha receptor agonists

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4
Q

Single-lit candle

A

alpha-1 agonist

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5
Q

3 dags

A

alpha-1 receptor coupled to Gq - IP3/DAG cascade

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6
Q

Dag with bone

A

IP3/DAG cascade leads to increased intracellular Ca (smooth muscle cell)

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7
Q

red leashes pulled tight

A

alpha-1 activation increases peripheral arterial resistance - vasoconstriction at small arteries, arterioles, precapillary sphincters

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8
Q

Alpha-1 scout elevating MAP

A

alpha-1 activation increases MAP

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9
Q

blue leashes pulled tight

A

alpha-1 activation increases venous return (venoconstriction) - useful when treating hypovolemic/distributive shock

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10
Q

Alpha-1 scout binoculars

A

alpha-1 activation at pupillary dilator muscle causes mydriasis

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11
Q

Alpha-1 scout pulling drawstring

A

alpha-1 activation causes urethral sphincter and prostatic smooth muscle contraction

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12
Q

Full bladder canteen

A

alpha-1 activation causes urinary retention

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13
Q

Two lit candles

A

alpha-2 agonist

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14
Q

“No Sympathy”

A

alpha-2 agonists are sympatholytics - act centrally to decrease sympathetic tone

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15
Q

Packed up alpha-2 camp tent

A

alpha-2 receptor coupled to Gi - decreased cAMP

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16
Q

Alpha-2 scout packing up presynaptic wire

A

presynaptic alpha-2 receptors cause inhibition of NT release

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17
Q

Rolled up Welcome Inside mat

A

alpha-2 activation at pancreatic islet cells decreases insulin release

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18
Q

Alpha-2 scout dousing roasting pig

A

alpha-2 activation inhibits lipolysis and release of fatty acids

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19
Q

Alpha-2 scout emptying water from eyeball hat

A

alpha-2 activation at ciliary body decreases aqueous humor production

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20
Q

Brim of eyeball hat

A

Brimonidine - alpha-2 agonist used to treat chronic open angle glaucoma - decrease aqueous humor production

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21
Q

Band camp

A

beta receptor agonists increase cAMP

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22
Q

Beta-1 bugle

A

Beta-1 agonist

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23
Q

I

A

beta-1 receptors found on cardiac myocytes (SA/AV node); increased cAMP = increased Ca

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24
Q

Elevated heart clock

A

beta-1 activation increases heart rate (SA node)

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25
Buff bicep
beta-1 activation increases cardiac contractility (myocytes)
26
Heart hydrant
beta-1 activation results in increased CO
27
Open rain umbrella
beta-1 activation increases renin release
28
Beta-2 tuba
beta-2 activity
29
Beta-2 camper taking big breath
beta-2 activation leads to broncho-dilation; increased cAMP = activates PKA
30
Beta-2 camper with dilated sleeves
Beta-2 activation causes coronary and skeletal muscle vasodilation - decreases TPR
31
Beta-2 camper with dangling DIAmond earrings
beta-2 activation decreases diastolic blood pressure
32
Beta-2 camper roasting pig
beta-2 activation stimulates lipolysis and release of FFA
33
Beta-2 camper producing marshmallows from liver-shaped bag
beta-2 activation at liver promotes gluconeogenesis
34
Welcome Inside mat
Beta-2 activation at pancreatic islet cells promotes insulin release
35
Banana peels
beta-2 activation can cause hypokalemia due to increased insulin
36
Beta-2 camper filling eyeball balloon
beta-2 activation at ciliary body increases aqueous humor production
37
Flannel friends
phenylephrine - alpha-1 agonist
38
Flannel friends nasal spray
phenylephrine treats nasal congestion - alpha-1 mediated vasoconstriction
39
Flannel friends binoculars
phenylephrine causes mydriasis - activates alpha-1 at pupillary dilator muscle
40
Flannel friends elevated MAP
Phenylephrine increases MAP - alpha-1 increase in TPR; increases SBP/DBP - used in shock
41
Flannel friends dangling heart watch
phenylephrine causes reflex bradycardia
42
North Compass
Norepinephrine - alpha1>beta1 agonist
43
North Scout blowing beta-1 bugle
NE has some beta-1 activity but primarily alpha agonist
44
North Scout elevated MAP
NE increases MAP, SBP, DBP
45
North Scout dangling heart watch
NE causes reflex bradycardia
46
North Scout buff contracted bicep
NE increases contractility through activation of beta-1
47
Septic tank
septic shock - phenylephrine and NE increase TPR and venous return to treat distributive/hypovolemic shock
48
Just DO BUgling shirt
Dobutamine (beta1 > beta2)
49
Just DO BUgling winding up heart flashlight
Dobutamine increases HR, contractility, CO
50
Just DO BUgling friend's beta-2 tuba
Dobutamine has beta-2 activity
51
Just DO BUgling MAP
Dobutamine increases pulse pressure, increases SBP, decreases DBP
52
Batteries out of heart flashlight
Dobutamine can be used in cardiogenic shock
53
Iso-pro-tunnel between beta-1/beta-2 camps
isoproterenol - beta1/beta2 agonist
54
Tunnel camper's elevated heart watch/contracted bicep
Isoproterenol increases HR and contractility
55
Tunnel camper's dilated sleeves
isoproterenol causes vasodilation - decreases TPR
56
Tunnel camper's dangling DIAmond earrings
isoproterenol decreases diastolic pressure
57
Tunnel between tents
Isoproterenol decreases MAP, decreases diastolic pressure which increases Pulse pressure
58
Sleeping beta-2 counselor
beta-2 agonists relax uterine smooth muscle
59
Do not disTURB
terbutaline prevents premature labor - relaxes uterus
60
I dream of band camp
Ritodrine prevents premature labor - relaxes uterus
61
Rol call sheet
beta-2 agonists used for bronchodilation have "rol" suffix
62
Epic kiss between alpha/beta camps
Epinephrine - beta > alpha agonist
63
Low side of Epic raft
Low doses - epinephrine's beta agonist effects predominate
64
Beta-2 tuba girl's epic inhaler
epinephrine causes bronchodilation (beta-2)
65
Epic diamond falling off low side of raft
low doses, epinephrine decreases diastolic pressure
66
Epic elevated heart watch and buff bicep
epinephrine increases HR/contractility (beta-1)
67
High side of raft
High doses of epinephrine, alpha agonist effects predominate
68
High side MAP
Epinephrine increases systolic pressure, decrease diastolic pressure, increase MAP and increase pulse pressure

Pharm 1 (6 decks)

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