Flashcards in Skin Cancer Deck (23):
What are the risk factors for non melanoma skin cancer?
X ray and thermal radiation
Human papilloma virus
Familial cancer syndromes
What is the clinical appearance of basal cell carcinoma?
Pearly rolled edge
What is the treatment for basal cell carcinoma?
What are the indications for vismodegib?
Locally advanced BCC not suitable for surgery or radiotherapy
What are the side effects of vismodegib?
What is the clinical appearance of squamous cell carcinoma?
What is the treatment for squamous cell carcinoma?
What is the criteria for a high risk squamous cell carcinoma?
Ear, nose, lip, eyelid
What is the origin of a keratoacanthoma?
Hair follicle in sun damaged skin
What is the treatment for keratoacanthoma?
What are the risk factors for melanoma skin cancer?
Fair skin, red hair, blue eyes
Tendency to burn easily
Familial melanoma and melanoma susceptibility genes
What is the ABCDE rule?
What are the major features of melanoma skin cancer?
Change in size
Change in shape
Change in colour
What are the minor features of melanoma skin cancer?
Diameter more than 5mm
Oozing or bleeding
Mild itch or altered sensation
What are some types of melanoma skin cancer?
Superficial spreading malignant melanoma
Lentigo maligna melanoma
Acral lentiginous melanoma
What is the treatment for melanoma skin cancer?
Urgent wide margin surgical excision (Breslow thickness)
Sentinel lymph node biopsy
Regular follow up
Primary and secondary prevention
What are the biologics used to treat metastatic melanoma?
What cells are can be affected by cutaneous lymphoma?
Cutaneous T cell
Cutaneous B cell
What are the different stages of mycosis fungoides?
What is sezary syndrome also known as?
Red man syndrome
What is the treatment for cutaneous lymphoma?
PUVA or UVB
Low dose methotrexate
Total skin electron beam therapy
Bone marrow transplantation
What are the steps of extracorporeal photophoresis?
Patients blood drawn and leucocytes collected
WBC mixed with psoralen, makes T cells sensitive to UVA radiation
Exposed to UVA radiation, damges diseased cells
Treated cells re infused back to patient